Patents by Inventor Kyle A. DiVito

Kyle A. DiVito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vascularized Skin Models
    Publication number: 20180072996
    Abstract: A synthetic skin tissue is served by at least one synthetic blood vessel and includes a physiologically representative population of cells including fibroblasts and keratinocytes, wherein some keratinocytes are in a differentiated state.
    Type: Application
    Filed: September 8, 2017
    Publication date: March 15, 2018
    Inventors: André A. Adams, Kyle A. DiVito
  • Modeling Blood-Brain Barrier in Vitro
    Publication number: 20180064527
    Abstract: Synthetic human blood vessels can be constructed using human brain derived endothelial cells and incorporated into a tissue model that contains astrocytes and other neurons and microglia. Multi-cell type microvessels incorporate cell types such as astrocytes and pericytes in order to construct a highly representative blood-brain barrier in vitro model with a functional lumen containing brain-derived microvascular endothelial cells and a polymer wall containing human astrocytes and/or pericytes.
    Type: Application
    Filed: September 7, 2017
    Publication date: March 8, 2018
    Inventors: André A. Adams, Kyle A. DiVito, Stella H. North, Michael A. Daniele