Patents by Inventor Kyle E. Parcella

Kyle E. Parcella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 2-phenyl (AZA)benzofuran compounds for the treatment of hepatitis C
    Patent number: 10214534
    Abstract: Compounds of Formula I, including their salts, as well as compositions and methods of using the compounds are set forth.
    Type: Grant
    Filed: June 10, 2015
    Date of Patent: February 26, 2019
    Assignee: Bristol-Myers Squibb Company
    Inventors: Tao Wang, Zhongxing Zhang, Kyle E. Parcella, Kyle J. Eastman, John F. Kadow
  • Substituted pyridines as inhibitors of human immunodeficiency virus replication
    Patent number: 10189816
    Abstract: Disclosed are compounds of Formula (I), including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: January 29, 2019
    Assignee: ViiV HEALTHCARE UK (NO. 5) LIMITED
    Inventors: Kyle J. Eastman, John F. Kadow, Kyle E. Parcella, B. Narasimhulu Naidu, Tao Wang, Zhiwei Yin, Zhongxing Zhang
  • PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20180230124
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV.
    Type: Application
    Filed: August 10, 2016
    Publication date: August 16, 2018
    Inventors: Kyle J. EASTMAN, John F. KADOW, B. Narasimhulu NAIDU, Kyle E. PARCELLA, Manoj PATEL, Prasanna SIVAPRAKASAM, Yong TU
  • 5-(N-BENZYL TETRAHYDROISOQUINOLIN-6-YL) PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20180230129
    Abstract: Disclosed are compounds of Formula (I), including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
    Type: Application
    Filed: August 10, 2016
    Publication date: August 16, 2018
    Inventors: Kyle J. EASTMAN, John F. KADOW, Kyle E. PARCELLA, B. Narasimhulu NAIDU, Tao WANG, Zhiwei YIN, Zhongxing ZHANG
  • PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20180147196
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
    Type: Application
    Filed: July 7, 2016
    Publication date: May 31, 2018
    Inventors: Kyle J. EASTMAN, John F. KADOW, B. Narasimhulu NAIDU, Kyle E. PARCELLA, Manoj PATEL, Yong TU
  • Furopyridine compounds for the treatment of hepatitis C
    Patent number: 9957278
    Abstract: Compounds of formula I, including their salts, as well as compositions and methods of using the compounds are set forth. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: May 1, 2018
    Assignee: Bristol-Myers Squibb Company
    Inventors: Tao Wang, Kyle J. Eastman, Zhongxing Zhang, Kyle E. Parcella, John F. Kadow
  • Inhibitors of human immunodeficiency virus replication
    Patent number: 9938271
    Abstract: The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: April 10, 2018
    Assignee: ViiV HEALTHCARE UK (NO.5) LIMITED
    Inventors: Kyle J. Eastman, John F. Kadow, B. Narasimhulu Naidu, Kyle E. Parcella, Kevin Peese
  • FUROPYRIDINE COMPOUNDS FOR THE TREATMENT OF HEPATITIS C
    Publication number: 20170247385
    Abstract: Compounds of formula I, including their salts, as well as compositions and methods of using the compounds are set forth. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
    Type: Application
    Filed: August 4, 2015
    Publication date: August 31, 2017
    Applicant: Bristol-Myers Squibb Company
    Inventors: Tao Wang, Kyle J. Eastman, Zhongxing Zhang, Kyle E. Parcella, John F. Kadow
  • Fused furans for the treatment of hepatitis C
    Patent number: 9738653
    Abstract: The disclosure provides compounds of formula I or II, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: August 22, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Kap-Sun Yeung, Kyle J. Eastman, Kyle E. Parcella
  • SUBSTITUTED 2-PHENYL (AZA)BENZOFURAN COMPOUNDS FOR THE TREATMENT OF HEPATITIS C
    Publication number: 20170121340
    Abstract: Compounds of Formula I, including their salts, as well as compositions and methods of using the compounds are set forth.
    Type: Application
    Filed: June 10, 2015
    Publication date: May 4, 2017
    Inventors: Tao WANG, Zhongxing Zhang, Kyle E. Parcella, Kyle J. Eastman, John F. Kadow
  • COMPOUNDS USEFUL AS IMMUNOMODULATORS
    Publication number: 20170107202
    Abstract: The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases.
    Type: Application
    Filed: October 11, 2016
    Publication date: April 20, 2017
    Inventors: KAP-SUN YEUNG, Timothy P. Connolly, David B. Frennesson, Katharine A. Grant-Young, Piyasena Hewawasam, David R. Langley, Zhaoxing Meng, Eric Mull, Kyle E. Parcella, Mark George Saulnier, Li-Qiang Sun, Alan Xiangdong Wang, Ningning Xu, Juliang Zhu, Paul Michael Scola
  • INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20170008887
    Abstract: The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
    Type: Application
    Filed: February 13, 2015
    Publication date: January 12, 2017
    Inventors: Kyle J. EASTMAN, John F. KADOW, B. Narasimhulu NAIDU, Kyle E. PARCELLA, Kevin PEESE
  • Cyano containing azabenzofuran compounds for the treatment of hepatitis C
    Patent number: 9249152
    Abstract: Compounds of Formula I, including their salts, as well as compositions and methods of using the compounds are set forth.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: February 2, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Tao Wang, Kyle J. Eastman, Zhongxing Zhang, Kyle E. Parcella, Zhiwei Yin, John F. Kadow
  • FUSED FURANS FOR THE TREATMENT OF HEPATITIS C
    Publication number: 20160024103
    Abstract: The disclosure provides compounds of formula I or II, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
    Type: Application
    Filed: March 12, 2014
    Publication date: January 28, 2016
    Inventors: KAP-SUN YEUNG, KYLE J. EASTMAN, KYLE E. PARCELLA
  • CYANO CONTAINING AZABENZOFURAN COMPOUNDS FOR THE TREATMENT OF HEPATITIS C
    Publication number: 20150266886
    Abstract: Compounds of Formula I, including their salts, as well as compositions and methods of using the compounds are set forth.
    Type: Application
    Filed: March 20, 2015
    Publication date: September 24, 2015
    Inventors: Tao Wang, Kyle J. Eastman, Zhongxing Zhang, Kyle E. Parcella, Zhiwei Yin, John F. Kadow
  • Compounds for the treatment of hepatitis C
    Patent number: 8962651
    Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: February 24, 2015
    Assignee: Bristol-Myers Squibb Company
    Inventors: Kyle J. Eastman, Kyle E. Parcella, John F. Kadow
  • Novel Compounds for the Treatment of Hepatitis C
    Publication number: 20140275154
    Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
    Type: Application
    Filed: March 11, 2014
    Publication date: September 18, 2014
    Inventors: Kyle J. Eastman, Kyle E. Parcella, John F. Kadow
  • Compounds for the treatment of hepatitis C
    Patent number: 8722688
    Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: May 13, 2014
    Assignee: Bristol-Myers Squibb Company
    Inventors: Kap-Sun Yeung, Kyle E. Parcella, John A. Bender, Brett R. Beno, Katharine A. Grant-Young, Ying Han, Piyasena Hewawasam, John F. Kadow, Andrew Nickel
  • Compounds for the treatment of hepatitis C
    Patent number: 8536338
    Abstract: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
    Type: Grant
    Filed: May 14, 2012
    Date of Patent: September 17, 2013
    Assignee: Bristol-Myers Squibb Company
    Inventors: Richard Pracitto, John F. Kadow, John A. Bender, Brett R. Beno, Katharine A. Grant-Young, Ying Han, Piyasena Hewawasam, Andrew Nickel, Kyle E. Parcella, Kap-Sun Yeung, Louis S. Chupak
  • Compounds for the Treatment of Hepatitis C
    Publication number: 20120316126
    Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
    Type: Application
    Filed: August 17, 2012
    Publication date: December 13, 2012
    Inventors: Kap-Sun Yeung, Kyle E. Parcella, John A. Bender, Brett R. Beno, Katharine A. Grant-Young, Ying Han, Piyasena Hewawasam, John F. Kadow, Andrew Nickel