Abstract: The present application relates to an occlusion device for occluding a left atrial appendage. The device has an expandable hollow body with an internal volume. The expandable body includes a proximal portion having a first diameter, wherein the proximal portion is arranged to sealingly engage against an opening of the left atrial appendage, a distal portion having a second diameter, wherein the distal portion is arranged to be positioned inside and at least partially fill the left atrial appendage and a central portion extending between the proximal and distal portion, wherein the central portion comprises a waist region with a third diameter. The third diameter of the waist region is smaller than the first diameter of the proximal portion and the second diameter of the distal portion.

Abstract: The techniques of this disclosure generally relate to a valve prosthesis including a one-piece molded valve comprising commissures and reinforcement members applied to the commissures. The reinforcement members provide reinforcement and strength to the commissures, e.g., from the stress applied by commissure stitching on the commissures.

Abstract: The techniques of this disclosure generally relate to a valve prosthesis having a prosthetic valve, a stent structure, and anti-migration spikes. The stent structure is coupled to the prosthetic valve and includes an inflow portion. The anti-migration spikes are attached to the inflow portion, the anti-migration spikes protruding radially outward and in an outflow direction from the inflow portion. The anti-migration spikes penetrate into tissue of the vessel, e.g., the aortic annulus of a patient's left ventricle, to prevent migration, i.e., undesirable movement, of the valve prosthesis within the vessel after deployment.

Abstract: The techniques of this disclosure generally relate to a valve prosthesis having a one piece molded prosthetic valve and a reinforcement member attached to the prosthetic valve directly adjacent a cylindrical inflow end of the prosthetic valve. The reinforcement member is additional material outside the leaflet belly region that gets attached directly to a stent structure to provide reinforcement and durability of the prosthetic valve.

Abstract: The techniques of this disclosure generally relate to a valve prosthesis including a one-piece molded valve having valve leaflets with free edges in a chevron down pattern. By forming the free edges in a chevron down pattern, pinwheeling of the prosthetic valve and the associated stress on the prosthetic valve is reduced.

Abstract: The techniques of this disclosure generally relate to a valve prosthesis include a prosthetic valve, a stent structure having suture slots, an outer skirt, and outer skirt sutures. The outer skirt sutures attach the outer skirt to the stent structure. The outer skirt sutures are located within the suture slots. By recessing the outer skirt sutures within the suture slots below an inner surface of the stent structure, contact between the outer skirt sutures and valve leaflets of the prosthetic valve is avoided. By avoiding contact between the outer skirt sutures and the valve leaflets, damage to the valve leaflets due to abrasive contact with the outer skirt sutures is prevented.