Patents by Inventor Kyle KINNEY

Kyle KINNEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED GUIDE RNA FOR REDUCING OFF-TARGET EDITING
    Publication number: 20260218173
    Abstract: Modified synthetic guide RNAs which can be used to broadly reduce off-target editing while retaining on-target editing efficiency
    Type: Application
    Filed: December 15, 2025
    Publication date: July 30, 2026
    Applicant: Integrated DNA Technologies, Inc.
    Inventors: Kyle KINNEY, Garrett R. RETTIG, Karthik MURUGAN
  • ADAPTERED-TAG BLOCKING OLIGONUCLEOTIDES
    Publication number: 20260049352
    Abstract: Described herein are compositions and methods for reducing adaptered-tag sequencing reads during the identification and nomination of on- and off-target CRISPR edited sites. One embodiment is a method for reducing adaptered-tag sequencing reads during the identification and nomination of on- and off-target CRISPR edited sites, the method comprising: contacting in an amplification reaction one or more adaptered-tag blocking oligonucleotides with an isolated genomic DNA having one or more tag sequences and adapter sequences; wherein the adaptered-tag blocking oligonucleotides comprise one or more blocking moieties and hybridize to adaptered-tag sequences at a junction region between the adapter and tag sequences to reduce amplification of the adaptered-tag sequences.
    Type: Application
    Filed: August 13, 2025
    Publication date: February 19, 2026
    Inventors: Kyle KINNEY, Rolf TURK, Garrett RETTIG
  • METHODS FOR NOMINATION OF NUCLEASE ON-/OFF-TARGET EDITING LOCATIONS, DESIGNATED "CTL-seq" (CRISPR Tag Linear-seq)
    Publication number: 20250257352
    Abstract: Described herein are methods for identifying and nominating on- and off-target CRISPR editing sites with improved accuracy and sensitivity.
    Type: Application
    Filed: February 28, 2025
    Publication date: August 14, 2025
    Inventors: Matthew MCNEILL, Rolf TURK, Garrett RETTIG, Ellen BLACK, Yongming SUN, Chris SAILOR, Yu WANG, Keith GUNDERSON, Kyle KINNEY
  • METHODS FOR NOMINATION OF NUCLEASE ON-/OFF-TARGET EDITING LOCATIONS, DESIGNATED "CTL-seq" (CRISPR Tag Linear-seq)
    Publication number: 20220025365
    Abstract: Described herein are methods for identifying and nominating on- and off-target CRISPR editing sites with improved accuracy and sensitivity.
    Type: Application
    Filed: July 22, 2021
    Publication date: January 27, 2022
    Inventors: Matthew MCNEILL, Rolf TURK, Garrett RETTIG, Ellen BLACK, Yongming SUN, Chris SAILOR, Yu WANG, Keith GUNDERSON, Kyle KINNEY