Patents by Inventor Kyle Koss

Kyle Koss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR LOCALIZATION OF GROWTH FACTORS
    Publication number: 20240245791
    Abstract: The present invention features compositions and methods for the localization and concentration of various growth factors (e.g., vascular endothelial growth factor (VEGF), or an angiopoietin-1 (ANG1) protein, or an angiopoietin-2 (ANG2) protein) within a scaffold structure. The present invention may also be used to promote the rebuilding of vasculature on de-celled organs (e.g., a kidney) or artificial organs.
    Type: Application
    Filed: June 2, 2022
    Publication date: July 25, 2024
    Inventors: Jason Wertheim, Kyle Koss, Yangxi Liu
  • Heparin conjugated to collagen-binding peptides for targeting to biological and synthetic tissues
    Patent number: 12036234
    Abstract: Disclosed are heparin conjugates comprising heparin conjugated to a peptide that binds to a protein of the extracellular matrix (ECM) of cellular tissue, such as a collagen-binding peptide that binds to collagen of the ECM. The disclosed heparin conjugates may be utilized in methods that include treating ECM material to incorporate the heparin conjugates and impart anticoagulant activity to the ECM. The disclosed heparin conjugates also may be formulated as pharmaceutical compositions for treating and/or preventing vascular injuries and conditions.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: July 16, 2024
    Assignee: Northwestern University
    Inventors: Guillermo A. Ameer, Jason A. Wertheim, Bin Jiang, Kyle Koss