Abstract: Bottles and containers and methods of use have been disclosed. In an aspect, the bottle comprises a body that includes a first end forming a first aperture and a second end forming a second aperture. The first aperture has a first diameter and the second aperture has a second diameter. The first diameter can be larger than the second diameter. The bottle further includes a first cap removably coupled to the first end of the body and a second cap removably coupled to the second end of the body.

Abstract: Production and maintenance of hematopoietic stem cells in in vitro culture systems has proven to be elusive. Disclosed herein are hematopoietic stem cell compositions that originate from organoids such as liver organoids. These organoids also comprise a rare type of immune cell that is not yet fully elucidated due to the difficulty in isolating said immune cell from biological samples. Also disclosed herein are methods of producing said hematopoietic stem cells and immune cells from organoids, as well as methods of expanding hematopoietic stem cells from other sources using these organoids.

Abstract: The present disclosure provides a pulley, comprising a cylindrical wall having an outer surface with a plurality of circumferential grooves configured to receive a corresponding plurality of ribs on an inner surface of an elastic belt, a web connected to an inner surface of the cylindrical wall, a central hub connected to the web, the central hub comprises a central opening sized to be press-fit onto a drive shaft, and a drive feature configured to mate with a drive tool, thereby facilitating rotation of the pulley using the drive tool.

Abstract: The instant disclosure relates to compositions derived from precursor cells, and methods of using such compositions, for the manufacture of hematopoietic stem cells (HSCs) or derivative immune cells. More particularly, methods for obtaining hematopoietic stem cells from organoid tissue or cultures comprising organoids are disclosed, wherein the organoid tissue or cultures comprise liver or colonic tissue derived from precursor cells (such as embryonic stem cells or induced pluripotent stem cells), via directed differentiation.

Abstract: A clamping hub includes a body and an aperture, defined by the body, configured to receive a shaft. The clamping hub also includes a clamp configured to secure the shaft in the aperture. the clamp includes a first deformable component that defines a first portion of the aperture and configured to, when deformed, change a size of the aperture and a second deformable component that defines a second portion of the aperture opposite from the first portion of the aperture and configured to, when deformed, change the size of the aperture.

Abstract: Bottles and containers and methods of use have been disclosed. In an aspect, the bottle comprises a body that includes a first end forming a first aperture and a second end forming a second aperture. The first aperture has a first diameter and the second aperture has a second diameter. The first diameter can be larger than the second diameter. The bottle further includes a first cap removably coupled to the first end of the body and a second cap removably coupled to the second end of the body.

Abstract: A clamping hub includes a body and an aperture, defined by the body, configured to receive a shaft. The clamping hub also includes a clamp configured to secure the shaft in the aperture. the clamp includes a first deformable component that defines a first portion of the aperture and configured to, when deformed, change a size of the aperture and a second deformable component that defines a second portion of the aperture opposite from the first portion of the aperture and configured to, when deformed, change the size of the aperture.

Abstract: The present disclosure provides a pulley, comprising a cylindrical wall having an outer surface with a plurality of circumferential grooves configured to receive a corresponding plurality of ribs on an inner surface of an elastic belt, a web connected to an inner surface of the cylindrical wall, a central hub connected to the web, the central hub comprises a central opening sized to be press-fit onto a drive shaft, and a drive feature configured to mate with a drive tool, thereby facilitating rotation of the pulley using the drive tool.

Abstract: A composition that includes one or more compounds represented by the formula wherein R1 and R2 are same or different and are the residue of an alkyl group having more than 10 carbon atoms wherein the composition has a viscosity (Kv100) from 2 to 300 at 100° C. as determined by ASTM D-445, and a viscosity index (VI) from ?100 to 300 as determined by ASTM D-2270. The disclosure also relates to a process for producing the composition, a lubricating oil base stock and lubricating oil containing the composition, and a method for improving oxidative stability of a lubricating oil by using as the lubricating oil a formulated oil containing the composition.