Patents by Inventor Kyle Lindstrom

Kyle Lindstrom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Intermediates for imidazonaphthyridines
    Publication number: 20080091010
    Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are disclosed.
    Type: Application
    Filed: December 6, 2007
    Publication date: April 17, 2008
    Applicant: Graceway Pharmaceuticals, LLC
    Inventors: John Gerster, Kyle Lindstrom, Stephen Crooks, Philip Heppner, Gregory Marszalek, Peter Maye, Bryon Merrill, John Mickelson, Michael Rice
  • Substituted Imidazo Ring Systems and Methods
    Publication number: 20070259881
    Abstract: Imidazo ring systems, which include, for example, imidazopyridine, imidazoquinoline, 6,7,8,9-tetrahydroimidazoquinoline, imidazonaphthyridine, and 6,7,8,9-tetrahydroimidazonaphthyridine compounds substituted at the 1-position and/or the 2-position, pharmaceutical compositions containing these compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
    Type: Application
    Filed: June 17, 2005
    Publication date: November 8, 2007
    Inventors: Joseph Dellaria, Tushar Kshirsagar, Shri Niwas, William Moser, Joan Moseman, Kyle Lindstrom, Azim Celebi, John Gerster, Philip Heppner, Joshua Wurst
  • Aryl substituted imidazonaphthyridines
    Publication number: 20070219228
    Abstract: Imidazonaphthyridine ring systems substituted with an aryl substituent, pharmaceutical compositions containing the compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
    Type: Application
    Filed: June 17, 2005
    Publication date: September 20, 2007
    Inventors: Shri Niwas, Bryon Merrill, Philip Heppner, Tushar Kshirsagar, Gregory Lundquist, David Amos, Kyle Lindstrom
  • IMIDAZONAPHTHYRIDINES
    Publication number: 20070167481
    Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Application
    Filed: March 28, 2007
    Publication date: July 19, 2007
    Inventor: Kyle Lindstrom
  • Alkoxy substituted imidazoquinolines
    Publication number: 20070060754
    Abstract: Imidazoquinoline compounds with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.
    Type: Application
    Filed: October 1, 2004
    Publication date: March 15, 2007
    Inventors: Kyle Lindstrom, Bryon Merrill, Chad Haraldson, Michael Rice, Tushar Kshirsagar, Philip Heppner, Joshua Wurst, Shri Niwas, Sarah Johannessen
  • ETHER SUBSTITUTED IMIDAZOPYRIDINES
    Publication number: 20060252792
    Abstract: Imidazopyridine compounds that contain an ether or thioether functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Application
    Filed: July 24, 2006
    Publication date: November 9, 2006
    Inventors: Joseph Dellaria, Kyle Lindstrom, Luke Dressel, Philip Heppner, John Jacobsen, Joan Moseman, William Moser, Matthew Radmer, Doris Stoermer
  • INTERMEDIATES FOR IMIDAZONAPHTHYRIDINES
    Publication number: 20060128674
    Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are disclosed.
    Type: Application
    Filed: February 13, 2006
    Publication date: June 15, 2006
    Inventors: John Gerster, Kyle Lindstrom, Stephen Crooks, Philip Heppner, Gregory Marszalek, Peter Maye, Bryon Merrill, John Mickelson, Michael Rice
  • ARYL SUBSTITUTED IMIDAZOQUINOLINES
    Publication number: 20060111387
    Abstract: Aryl substituted imidazoquinoline compounds, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.
    Type: Application
    Filed: January 13, 2006
    Publication date: May 25, 2006
    Inventors: David Hays, Tushar Kshirsagar, Philip Heppner, Bryon Merrill, Michael Danielson, John Gerster, Chad Haraldson, Sarah Johannessen, Maureen Kavanagh, Kyle Lindstrom, Michael Rice, David Squire, Sarah Strong, Joshua Wurst
  • IMIDAZONAPHTHYRIDINES
    Publication number: 20050288320
    Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Application
    Filed: July 25, 2005
    Publication date: December 29, 2005
    Inventors: John Gerster, Kyle Lindstrom, Stephen Crooks, Philip Heppner, Gregory Marszalek, Peter Maye, Bryon Merrill, John Mickelson, Michael Rice
  • Amide substituted imidazopyridines
    Publication number: 20050282854
    Abstract: Imidazopyridine compounds that contain amide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Application
    Filed: August 10, 2005
    Publication date: December 22, 2005
    Inventors: Philip Heppner, Kyle Lindstrom, Bryon Merrill
  • Process for imidazo[4,5-c]pyridin-4-amines
    Publication number: 20050245516
    Abstract: A process and intermediates for preparing 1H-imidazo[4,5-c]pyridin-4-amines are disclosed. The process includes providing a 7H-imidazo[4,5-c]tetrazolo[1,5-a]pyridine and converting a 7H-imidazo[4,5-c]tetrazolo[1,5-a]pyridine to a 1H-imidazo[4,5-c]pyridin-4-amine.
    Type: Application
    Filed: July 8, 2005
    Publication date: November 3, 2005
    Inventors: Kyle Lindstrom, Luke Dressel
  • Sulfonamide and sulfamide substituted imidazoquinolines
    Publication number: 20050197358
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain sulfonamide or sulfonamide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Application
    Filed: April 7, 2005
    Publication date: September 8, 2005
    Inventor: Kyle Lindstrom
  • Urea substituted imidazoquinolines
    Publication number: 20050131009
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain urea, thiourea, acylurea, or sulfonylurea functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Application
    Filed: January 20, 2005
    Publication date: June 16, 2005
    Inventors: Stephen Crooks, George Griesgraber, Kyle Lindstrom, Bryon Merrill, Michael Rice
  • Imidazonaphthyridines
    Publication number: 20050107421
    Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Application
    Filed: December 3, 2004
    Publication date: May 19, 2005
    Inventors: John Gerster, Kyle Lindstrom, Stephen Crooks, Philip Heppner, Gregory Marszalck, Peter Maye, Bryon Merrill, John Mickelson, Michael Rice
  • Process for preparing imidazoquinolinamines
    Publication number: 20050096470
    Abstract: A process for preparing 1H-imidazo[4,5-c]quinolin-4-amines is disclosed. The process involves reacting a 6H-imidazo[4,5-c]tetrazolo[1,5-a]quinoline with triphenylphosphine and hydrolyzing the product thereof.
    Type: Application
    Filed: October 27, 2004
    Publication date: May 5, 2005
    Inventors: John Gerster, Kyle Lindstrom
  • Process for imidazo[4,5-c]pyridin-4-amines
    Publication number: 20050032829
    Abstract: A process and intermediates for preparing 1H-imidazo[4,5-c]pyridin-4-amines are disclosed. The process includes providing a 7H-imidazo[4,5-c]tetrazolo[1,5-a]pyridine and converting a 7H-imidazo[4,5-c]tetrazolo[1,5-a]pyridine to a 1H-imidazo[4,5-c]pyridin-4-amine.
    Type: Application
    Filed: May 28, 2004
    Publication date: February 10, 2005
    Inventors: Kyle Lindstrom, Luke Dressel, Jason Bonk
  • Ether substituted imidazopyridines
    Publication number: 20050032830
    Abstract: Imidazopyridine compounds that contain an ether or thioether functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Application
    Filed: August 11, 2004
    Publication date: February 10, 2005
    Inventors: Joseph Dellaria, Kyle Lindstrom, Luke Dressel, Daniel Duffy, Philip Heppner, John Jacobsen, Joan Moseman, William Moser, Matthew Radmer, Doris Stoermer, Bernhard Zimmermann
  • Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof
    Publication number: 20050026943
    Abstract: Thiazolo-, oxazolo- and selenazolo[4,5-c]quinolin-4-amines and analogs thereof are described including methods of manufacture and the use of novel intermediates. The compounds are immunomodulators and induce cytokine biosynthesis, including interferon and/or tumor biosynthesis, necrosis factor, and inhibit the T-helper-type 2 immune response. The compounds are further useful in the treatment of viral and neoplastic diseases.
    Type: Application
    Filed: August 25, 2004
    Publication date: February 3, 2005
    Inventors: John Gerster, Kyle Lindstrom, Gregory Marszalek, Michael Rice