Patents by Inventor Kyle MCELEARNEY

Kyle MCELEARNEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hypotaurine, GABA, Beta-Alanine, and Choline for Control of Waste Byproduct Accumulation in Mammalian Cell Culture Process
    Publication number: 20170327786
    Abstract: The present invention pertains to a cell culture medium comprising hypotaurine, GABA, and/or beta-alanine or the combination of choline and hypotaurine, GABA, and/or beta-alanine as media supplements which is shown to control viability, growth, and waste byproduct accumulation. The present invention further pertains to a method of producing a polypeptide of interest in a large scale cell culture containing hypotaurine, GABA, and/or beta-alanine or the combination of choline and hypotaurine, GABA, and/or beta-alanine.
    Type: Application
    Filed: October 30, 2015
    Publication date: November 16, 2017
    Applicant: Biogen MA Inc.
    Inventors: Yao-Ming HUANG, William C. YANG, Alan GILBERT, Kyle MCELEARNEY
  • Medium Supplements for Improved Process Performance
    Publication number: 20150353883
    Abstract: The present invention pertains to a cell culture medium comprising dextran sulfate or a mixture of dextran sulfate and ferric citrate, and methods of using thereof. The present invention further pertains to a method of producing a protein of interest in a large scale cell culture, comprising supplementing the cell culture with dextran sulfate or a mixture of dextran sulfate and ferric citrate.
    Type: Application
    Filed: January 10, 2014
    Publication date: December 10, 2015
    Inventors: Alan GILBERT, Kyle MCELEARNEY, Terrence Michael DOBROWSKY, Rashmi Rohit KSHIRSAGAR