Abstract: A method including generating a first vector based on a first grid and a three-dimensional (3D) position associated with a first implicit representation (IR) of a 3D object, generating at least one second vector based on at least one second grid and an upsampled first grid, decoding the first vector to generate a second IR of the 3D object, decoding the at least one second vector to generate at least one third IR of the 3D object, generating a composite IR of the 3D object based on the second IR of the 3D object and the at least one third IR of the 3D object, and generating a reconstructed volume representing the 3D object based on the composite IR of the 3D object.

Abstract: Examples of augmented reality (AR) environment control advantageously employ multi-factor intention determination and include: performing a multi-factor intention determination for summoning a control object (e.g., a menu, a keyboard, or an input panel) using a set of indications in an AR environment, the set of indications comprising a plurality of indications (e.g., two or more of a palm-facing gesture, an eye gaze, a head gaze, and a finger position simultaneously); and based on at least the set of indications indicating a summoning request by a user, displaying the control object in a position proximate to the user in the AR environment (e.g., docked to a hand of the user). Some examples continue displaying the control object while at least one indication remains, and continue displaying the control object during a timer period if one of the indications is lost.

Abstract: A blank of flat corrugated board is formed with a longitudinal perforation or crease to enable folding into an angle board. A double coated tape strip is adhered on the flat body opposite the perforation or over the crease and a release layer is disposed over said tape strip. After removal of the release layer, the flat board may be folded into an angle board shape with the adhesive maintaining the folded sections of the flat body together.

Abstract: Provided is a compound of formula (I) in which Ar1, R1, U, V, W, X, and p are as described herein. Also provided are methods of using a compound of formula (I), including a method of treating cancer, a method of treating a patient with cancer cells resistant to an anti-cancer agent, and a method of inhibiting lactate dehydrogenase A (LDHA) and/or lactate dehydrogenase B (LDHB) activity in a cell.

Abstract: Provided is a compound of formula (I) in which Ar1, R1, U, V, W, X, and p are as described herein. Also provided are methods of using a compound of formula (I), including a method of treating cancer, a method of treating a patient with cancer cells resistant to an anti-cancer agent, and a method of inhibiting lactate dehydrogenase A (LDHA) and/or lactate dehydrogenase B (LDHB) activity in a cell.

Abstract: A computing system runs a productivity application that maintains an integrated, time ordered revision/undo stack. Entries in the revision/undo stack identify revision operations that a user has made to a document and corresponding undo operations that can be executed to undo the revision operation. The computing system detects an undo input indicative of a user actuating un undo actuator to undo a previous operation, that is prior to a most current operation that the user has performed. An operational transform system identifies an undo operation in the undo stack, corresponding to the revision that the user selected in the revision/undo stack. The operational transform system traverses the revision/undo stack to identify subsequent operations that were performed subsequent to the previous operation, and identifies one or more transforms to be applied to the undo operation based upon the identified subsequent operations.

Abstract: Provided is a compound of formula (I), in which Ar1, R1, U, V, W, X, and p are as described herein. Also provided are methods of using a compound of formula (I), including a method of treating cancer, a method of treating a patient with cancer cells resistant to an anti-cancer agent, and a method of inhibiting lactate dehydrogenase A (LDHA) and/or lactate dehydrogenase B (LDHB) activity in a cell.

Abstract: An Integrated Hybrid Compact Fluid Heat Exchanger is disclosed. An example embodiment includes: a micro-channeled plate for a stream of a working fluid, the micro-channeled plate being diffusion bonded or brazed with a cover plate; and a fin assembly brazed, diffusion bonded, or welded to the micro-channeled plate. Other embodiments include a fan or blower coupled to the Integrated Hybrid Compact Fluid Heat Exchanger via air ducting or close coupling.

Abstract: The present invention is a camera with video-rate acquisition and processing for medical imaging applications. In particular, the invention is used to determine the health of a body area by quantitatively measuring blood oxygen levels and melanin content from a real-time video image of a body segment. In certain embodiments, a camera comprises an objective lens; a filter tray located at an aperture stop of the objective lens, wherein the filter tray comprises a plurality of elements, each element passes a spectral band of light; a micro-lens array located at an exit pupil of the objective lens comprising a plurality of micro lenses to form an image plane, wherein the objective lens produces a focused image at the image plane; and a focal plane array comprising a plurality of sensors, wherein each sensor receives light from at least one micro-lens of the micro-lens array.

Abstract: Provided is a compound of formula (I)[Formula (I) should be inserted here], in which Ar1, R1, U, V, W, X, and p are as described herein. Also provided are methods of using a compound of formula (I), including a method of treating cancer, a method of treating a patient with cancer cells resistant to an anti-cancer agent, and a method of inhibiting lactate dehydrogenase A (LDHA) and/or lactate dehydrogenase B (LDHB) activity in a cell.

Abstract: The present invention is a camera with video-rate acquisition and processing for medical imaging applications. In particular, the invention is used to determine the health of a body area by quantitatively measuring blood oxygen levels and melanin content from a real-time video image of a body segment. In certain embodiments, a camera comprises an objective lens; a filter tray located at an aperture stop of the objective lens, wherein the filter tray comprises a plurality of elements, each element passes a spectral band of light; a micro-lens array located at an exit pupil of the objective lens comprising a plurality of micro lenses to form an image plane, wherein the objective lens produces a focused image at the image plane; and a focal plane array comprising a plurality of sensors, wherein each sensor receives light from at least one micro-lens of the micro-lens array.

Abstract: Provided is a compound of formula (I) in which Ar1, R1, U, V, W, X, and p are as described herein. Also provided are methods of using a compound of formula (I), including a method of treating cancer, a method of treating a patient with cancer cells resistant to an anti-cancer agent, and a method of inhibiting lactate dehydrogenase A (LDHA) and/or lactate dehydrogenase B (LDHB) activity in a cell.

Abstract: The disclosure provides a compound of the formula (II) and pharmaceutically acceptable salts thereof. The variables, e.g. n, R, R3, R10, X, Y, and Z are defined herein. These compounds act as lactate dehydrogenase inhibitors and are useful for treating cancer and fibrosis. The compounds may be particularly useful for treating forms of cancer in which a metabolic switch from oxidative phosphorylation to glycolysis has occurred. The disclosure also provides pharmaceutical compositions containing a compound of this formula and method for treating patients having cancer, fibrosis, or other conditions in which a metabolic switch from oxidative phosphorylation to glycolysis has occurred.

Abstract: A compound of Formula II or a pharmaceutically acceptable salt thereof, wherein CyN is a cyclic amine group bound via a nitrogen atom; X is C or N; R1 and R2 are each independently a halogen, CN, CF3, CHF2, CH2F, a C1-C10alkyl group, a C1-C10alkoxy group, a di(C1-C5alkyl)amino; m and n are each independently 1, 2, or 3, and represents either a single bond or a double bond, wherein the racemic mixture of 3-(4-(4-chlorophenyl)thiazol-2-yl)-1-(2-ethyl-5-methoxyphenyl)-6-(2-methylprop-1-en-1-yl)-5-(piperazine-1-carbonyl)pyridin-2(1H)-one atropisomers is excluded.

Abstract: A web application provides a custom selection for editing text on a gesture or touch screen. The application replaces native browser handles with selection handles to provide consistent user interface experience across platforms. The application also provides a scheme for semantic interpretation of browser gesture or touch events. The application standardizes browser events into a consistent stream of semantic events that are compatible with a plurality of devices and browsers. The application also provides a gesture or touch optimized user interface in the browser. The application determines gesture or touch input and optimizes the user interface according to the type of input.

Abstract: Compounds of Formula I and Formula II and the pharmaceutically acceptable salts thereof are disclosed The variables A, B, Y, Z, X1, X2, R1-4 and R13-18 are disclosed herein. The compounds are useful for treating cancer disorders, especially those involving mutant IDH1 enzymes. Pharmaceutical compositions containing compounds of Formula I or Formula II and methods of treatment comprising administering compounds of Formula I and Formula II are also disclosed.

Abstract: A thermal receiver, such as a solar flux thermal receiver, is disclosed comprising a modular arrangement of arrayed microchannels or micropins to heat a working fluid by heat transfer. Disclosed solar receivers provide a much higher solar flux and consequently a significant reduction in thermal losses, size, and cost, relative to known receivers. Unit cell receivers can be numbered up and combined in parallel to form modules, and modules combined to form full scale receivers.

Abstract: Provided is a compound of formula (I) in which Ar1, R1, U, V, W, X, and p are as described herein. Also provided are methods of using a compound of formula (I), including a method of treating cancer, a method of treating a patient with cancer cells resistant to an anti-cancer agent, and a method of inhibiting lactate dehydrogenase A (LDHA) and/or lactate dehydrogenase B (LDHB) activity in a cell.

Abstract: The invention provides an alarm comprising: (i) a plurality of trackside sensors with known locations each sensor to measure at least one characteristic of each railcar wheelset as it passes that sensor's location; (ii) an information store to receive, store and later provide the railcar wheelset characteristics measured by the track-side sensors; (iii) a preset or predetermined trigger pattern of wheelset characteristics associated with wheelset failure or some other railcar condition requiring alarm or notification action; and (iv) a comparator to compare historical measured characteristics about a particular wheelset from the information store to the trigger pattern. The alarm is triggered responsive to a comparator indication of a suitable match between chronologically contiguous historical measured characteristics about a particular wheelset in the information store with the trigger pattern.