Abstract: A vibratory myofascial decompression apparatus includes a cup and at least one electrically operated vibration element positioned external to the cup. The cup includes a cup body defining an internal cavity and a lip that defines an opening into the internal cavity, with the lip being configured to contact a skin surface of a user. A housing engages an exterior of the cup body. The cup also includes an exhaust port positioned inside the internal cavity configured to permit air to be withdrawn from the internal cavity. The at least one electrically operated vibration element is coupled with the cup to permit vibration to be transmitted through the cup body and the lip to the skin of the user.

Abstract: This disclosure relates generally to mechanical surgical arms having a connector for attaching a surgical tool to the arm across a sterile drape. In various aspects, a drape connector for securing a tool to a surgical arm across a sterile drape includes a flexible collet for receiving a ball of a connection shank of the surgical arm to selectively secure the flexible collet to the surgical arm. The drape connector may also include a lock associated with an inferior end of the flexible collet. The lock may be for adjusting the flexible collet from an unlocked position to a locked position. Further, the drape connector may include a housing for receiving the flexible collet and the lock. The housing defines a window to provide access to the lock to adjust the flexible collet from the unlocked to the locked position.

Abstract: A non-ratcheting surgical clip application device for applying and crimping surgical clips to ligate a vessel. The surgical clip applying device includes an enclosure formed from a top housing, a bottom housing and a window cover, a pair of handles including a left handle and a right handle each mounted for pivotal movement in the bottom housing, a main rail fixedly mounted to the bottom housing within the enclosure, a pair of clip applying jaws fixedly attached to the bottom housing and mounted through the main rail, a jaw closer comprising a proximal end, a distal end, and an elongate base, and a drive mechanism including a plurality of levers and at least one spring.

Abstract: One or more methods for automated preparation of a regenerative epidermal suspension comprises a processor receiving an initiation signal that indicates that a cartridge that has a cover, a cup containing a tissue sample, and a well plate situated beneath the cover that has a first well containing an enzyme solution and a second well containing a buffer solution, has been placed on a sensor, executing a sequence that actuates a tissue disaggregator against the tissue sample in the cup positioned in the first well, raises the cup to an upper position, rotates the well plate to position the second well beneath the cup, lowers the cup to a position within the second well, and actuates the tissue disaggregator against the tissue sample in the second well.

Abstract: A surgical clip application device for applying and crimping surgical clips to ligate a vessel.

Abstract: Disclosed herein are systems and devices for wound therapy and related methods of use. The systems and devices for wound therapy and related methods of use disclosed herein may comprise one or more cartridges for preparation of a regenerative epidermal suspension. One or more cartridges for preparation of a regenerative epidermal suspension may comprise a cover with a raised processing opening, a cup that can be received within the raised processing opening and has a screen, and a well plate that is positioned under the cover, has a well, and rotates relative to the cover such that the well aligns with the raised processing opening. One or more cartridges for preparation of a regenerative epidermal suspension comprises a cover with an opening that can receive a tissue sample.

Abstract: A surgical clip application device for applying and crimping surgical clips to ligate a vessel.

Abstract: One or more systems for automated preparation of a regenerative epidermal suspension comprises a base unit, a cartridge assembly containing a cup, and a tissue disaggregator. The system may also include related tools. The system executes one or more sequences wherein a first motor actuates the pestle against a tissue sample that is disposed along a screen within the cup while the tissue sample is in contact with, in sequence, an enzyme solution, a first buffer solution, and then a second buffer solution. To transition between fluidic contact stages or steps, the tissue disaggregator engages with and lifts the cup into a raised position within a processing area of the cartridge while a base plate motor rotates the appropriate well into alignment under the cup for each processing step. Once the sequence is complete, a user may draw up a regenerative epidermal suspension through an opening in the cartridge top cover.

Abstract: One or more methods for automated preparation of a regenerative epidermal suspension comprises a processor receiving an initiation signal that indicates that a cartridge that has a cover, a cup containing a tissue sample, and a well plate situated beneath the cover that has a first well containing an enzyme solution and a second well containing a buffer solution, has been placed on a sensor, executing a sequence that actuates a tissue disaggregator against the tissue sample in the cup positioned in the first well, raises the cup to an upper position, rotates the well plate to position the second well beneath the cup, lowers the cup to a position within the second well, and actuates the tissue disaggregator against the tissue sample in the second well.

Abstract: One or more methods for treating a tissue site comprises collecting a tissue sample that has keratinoytes and placing the tissue sample in a cartridge that has a well plate, positioning the cartridge within a base unit that has a tissue disaggregator, activating the base unit to rotate the well plate to align wells in the well plate with the tissue sample and the tissue disaggregator, operate the tissue disaggregator to separate the tissue sample to form a regenerative epidermal suspension, and provide the regenerative epidermal suspension to a tissue site to enhance healing of the tissue site.

Abstract: One or more systems for automated preparation of a regenerative epidermal suspension comprises a base unit, a cartridge assembly containing a cup, and a tissue disaggregator. The system may also include related tools. The system executes one or more sequences wherein a first motor actuates the pestle against a tissue sample that is disposed along a screen within the cup while the tissue sample is in contact with, in sequence, an enzyme solution, a first buffer solution, and then a second buffer solution. To transition between fluidic contact stages or steps, the tissue disaggregator engages with and lifts the cup into a raised position within a processing area of the cartridge while a base plate motor rotates the appropriate well into alignment under the cup for each processing step. Once the sequence is complete, a user may draw up a regenerative epidermal suspension through an opening in the cartridge top cover.

Abstract: One or more methods for automated preparation of a regenerative epidermal suspension comprises a processor receiving an initiation signal that indicates that a cartridge that has a cover, a cup containing a tissue sample, and a well plate situated beneath the cover that has a first well containing an enzyme solution and a second well containing a buffer solution, has been placed on a sensor, executing a sequence that actuates a tissue disaggregator against the tissue sample in the cup positioned in the first well, raises the cup to an upper position, rotates the well plate to position the second well beneath the cup, lowers the cup to a position within the second well, and actuates the tissue disaggregator against the tissue sample in the second well.

Abstract: One or more methods for treating a tissue site comprises collecting a tissue sample that has keratinoytes and placing the tissue sample in a cartridge that has a well plate, positioning the cartridge within a base unit that has a tissue disaggregator, activating the base unit to rotate the well plate to align wells in the well plate with the tissue sample and the tissue disaggregator, operate the tissue disaggregator to separate the tissue sample to form a regenerative epidermal suspension, and provide the regenerative epidermal suspension to a tissue site to enhance healing of the tissue site.

Abstract: One or more cartridges for preparation of a regenerative epidermal suspension comprises a cover with a raised processing opening, a cup that can be received within the raised processing opening and has a screen, and a well plate that is positioned under the cover, has a well, and rotates relative to the cover such that the well aligns with the raised processing opening. One or more cartridges for preparation of a regenerative epidermal suspension comprises a cover with an opening that can receive a tissue sample.

Abstract: Learning systems and methods of the present disclosure include generating a text document based on a digital file, tokenizing the text document, generating a semantic model based on the tokenized text document using an unsupervised machine learning algorithm, assigning a plurality of passage scores to a corresponding plurality of passages of the tokenized text document, selecting one or more candidate knowledge items from the tokenized text document based on the plurality of passage scores, filtering the one or more candidate knowledge items based on user data, generating one or more structured learning assets based on the one or more filtered candidate knowledge items, generating an interaction based at least on the one or more structured learning assets, and transmitting the interaction to a user device. Each passage score is assigned based on a relationship between a corresponding passage and the semantic model.

Abstract: A surgical clip application device for applying and crimping surgical clips to ligate a vessel.

Abstract: A learning system includes a non-transitory memory, and one or more hardware processors configured or programmed to read instructions from the non-transitory memory to cause the learning system to perform operations including generating a user knowledge mesh including generating topic nodes each corresponding to a topic included in the user knowledge mesh, and generating concept nodes each corresponding to a key learnable concept, wherein each of the topic nodes is connected to another one of the topic nodes, each of the concept nodes is connected to one of the topic nodes, and each of the key learnable concepts includes one or more interactions related to the key learnable concept.

Abstract: Learning systems and methods of the present disclosure include generating a text document based on a digital file, tokenizing the text document, generating a semantic model based on the tokenized text document using an unsupervised machine learning algorithm, assigning a plurality of passage scores to a corresponding plurality of passages of the tokenized text document, selecting one or more candidate knowledge items from the tokenized text document based on the plurality of passage scores, filtering the one or more candidate knowledge items based on user data, generating one or more structured learning assets based on the one or more filtered candidate knowledge items, generating an interaction based at least on the one or more structured learning assets, and transmitting the interaction to a user device. Each passage score is assigned based on a relationship between a corresponding passage and the semantic model.

Abstract: Learning systems and methods of the present disclosure include generating a text document based on a digital file, tokenizing the text document, generating a semantic model based on the tokenized text document using an unsupervised machine learning algorithm, assigning a plurality of passage scores to a corresponding plurality of passages of the tokenized text document, selecting one or more candidate knowledge items from the tokenized text document based on the plurality of passage scores, filtering the one or more candidate knowledge items based on user data, generating one or more structured learning assets based on the one or more filtered candidate knowledge items, generating an interaction based at least on the one or more structured learning assets, and transmitting the interaction to a user device. Each passage score is assigned based on a relationship between a corresponding passage and the semantic model.

Abstract: A learning system includes a non-transitory memory, and one or more hardware processors configured or programmed to read instructions from the non-transitory memory to cause the learning system to perform operations including generating a user knowledge mesh including generating topic nodes each corresponding to a topic included in the user knowledge mesh, and generating concept nodes each corresponding to a key learnable concept, wherein each of the topic nodes is connected to another one of the topic nodes, each of the concept nodes is connected to one of the topic nodes, and each of the key learnable concepts includes one or more interactions related to the key learnable concept.