Patents by Inventor Kyle Tipton

Kyle Tipton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETING SEQUENCES FOR PAENIBACILLUS-BASED ENDOSPORE DISPLAY PLATFORM
    Publication number: 20220235315
    Abstract: Signal sequences useful for targeting proteins and peptides to the surface of endospores produced by Paenibacillus family members and methods of using the same are provided. The display of heterologous molecules, such as peptides, polypeptides and other recombinant constructs, on the spore surface of Paenibacillus family members, using particular N-terminal targeting sequences and derivatives of the same, and likewise are provided.
    Type: Application
    Filed: May 15, 2020
    Publication date: July 28, 2022
    Inventors: Damian CURTIS, Kyle TIPTON
  • Bacterial protein compositions and uses thereof
    Patent number: 11291712
    Abstract: Disclosed herein is an attenuated Acinetobacter baumannii comprising an expression vector comprising a nucleic acid encoding the ABUW_1645 protein or a variant thereof. Disclosed herein are methods of treating or preventing colonization, infection, or disease by an Acinetobacter baumannii microbe, the method comprising administering a clinically effective dose of the attenuated Acinetobacter baumannii to a subject in need thereof, wherein the attenuated Acinetobacter baumannii comprises an expression vector expressing the ABUW_1645 protein or variants thereof.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: April 5, 2022
    Assignee: THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Philip Rather, David Weiss, Chui-Yoke Chin, Kyle Tipton
  • ENDOSPORE DISPLAY PLATFORMS, PRODUCTS AND METHODS
    Publication number: 20220002736
    Abstract: Signal sequences useful for targeting proteins and peptides to the surface of endospores produced by Brevibacillus, Lysinibacillus, or Viridibacillus family members and methods of using the same are provided. The display of heterologous molecules, such as peptides, polypeptides and other recombinant constructs, on the exosporium of Brevibacillus, Lysinibacillus, or Viridibacillus family members, using particular N-terminal targeting sequences and derivatives of the same, and likewise are provided.
    Type: Application
    Filed: November 15, 2019
    Publication date: January 6, 2022
    Inventors: Benjamin L. GOLOMB, Florencia A. FICARRA, Rauf SALAMZADE, Damian CURTIS, Kyle TIPTON, Dilara ALLY
  • BACTERIAL PROTEIN COMPOSITIONS AND USES THEREOF
    Publication number: 20200276293
    Abstract: Disclosed herein is an attenuated Acinetobacter baumannii comprising an expression vector comprising a nucleic acid encoding the ABUW_1645 protein or a variant thereof. Disclosed herein are methods of treating or preventing colonization, infection, or disease by an Acinetobacter baumannii microbe, the method comprising administering a clinically effective dose of the attenuated Acinetobacter baumannii to a subject in need thereof, wherein the attenuated Acinetobacter baumannii comprises an expression vector expressing the ABUW_1645 protein or variants thereof.
    Type: Application
    Filed: September 19, 2018
    Publication date: September 3, 2020
    Inventors: Philip Rather, David Weiss, Chui-Yoke Chin, Kyle Tipton