Patents by Inventor Kyohei MATSUSHITA
Kyohei MATSUSHITA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180326042Abstract: The present invention provides a dried influenza vaccine preparation in which the activity of an influenza vaccine can be stably maintained even if the preparation is stored without strict temperature control and which can be stably supplied. The present invention also provides a method for producing the dried influenza vaccine preparation. Provided is a dried influenza vaccine preparation including: an influenza vaccine antigen; a disaccharide; and an-amino acid.Type: ApplicationFiled: November 28, 2016Publication date: November 15, 2018Applicant: NITTO DENKO CORPORATIONInventors: Eiji KIYOTOH, Mitsuhiko HORI, Daisuke ASARI, Katsuyuki OKUBO, Takuya SHISHIDO, Masahiro FUKASAKA, Kyohei MATSUSHITA
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Patent number: 10092642Abstract: The present invention aims at providing a mucosal vaccine composition that can be administered to an intraoral mucous membrane, ocular mucous membrane, ear mucous membrane, genital mucous membrane, pharyngeal mucous membrane, respiratory tract mucous membrane, bronchial mucous membrane, pulmonary mucous membrane, gastric mucous membrane, enteric mucous membrane, or rectal mucous membrane, that is useful as a prophylactic or therapeutic agent for infectious diseases or cancers, and is capable of safely and effectively inducing the systemic immune response and mucosal immune response.Type: GrantFiled: October 2, 2014Date of Patent: October 9, 2018Assignee: NITTO DENKO CORPORATIONInventors: Masahiro Fukasaka, Mitsuhiko Hori, Katsuyuki Okubo, Daisuke Asari, Arimichi Okazaki, Eiji Kiyotoh, Kyohei Matsushita
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Patent number: 10076491Abstract: The invention provides a vaccine composition containing an antigen for inducing cellular immunity, comprising at least one first cellular immunity induction promoter.Type: GrantFiled: January 29, 2014Date of Patent: September 18, 2018Assignee: NITTO DENKO CORPORATIONInventors: Daisuke Asari, Katsuyuki Okubo, Takuya Shishido, Arimichi Okazaki, Yoshiki Maeda, Kyohei Matsushita, Wenjing Li, Mitsuhiko Hori, Haruo Sugiyama
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Patent number: 10071155Abstract: The present invention provides a nasal mucosal vaccine composition which is safe, useful as a preventive or therapeutic agent for infectious diseases or cancers, and capable of inducing systemic immune responses and mucosal immune responses effectively.Type: GrantFiled: October 2, 2014Date of Patent: September 11, 2018Assignee: NITTO DENKO CORPORATIONInventors: Eiji Kiyotoh, Mitsuhiko Hori, Katsuyuki Okubo, Daisuke Asari, Arimichi Okazaki, Masahiro Fukasaka, Kyohei Matsushita
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Publication number: 20180169227Abstract: The present invention provides an immunity induction-promoting composition which has a track record of use as a medicine or medicinal additive and is capable of safely and effectively inducing cellular immune response, and a vaccine pharmaceutical composition containing the immunity induction-promoting composition. The present invention relates to an immunity induction-promoting composition containing an immunity induction promoter whose active ingredient is an antimicrobial drug.Type: ApplicationFiled: August 3, 2016Publication date: June 21, 2018Applicant: NITTO DENKO CORPORATIONInventors: Kyohei MATSUSHITA, Daisuke ASARI, Takuya SHISHIDO, Mitsuhiko HORI
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Publication number: 20180147235Abstract: The present invention provides an allergy vaccine composition that is useful as a prophylactic or therapeutic agent for an allergic disease and can safely and effectively induce immune tolerance. The vaccine composition is to be administered to a human or animal with an allergic disease for the prevention or treatment of the allergic disease.Type: ApplicationFiled: April 28, 2016Publication date: May 31, 2018Applicant: NITTO DENKO CORPORATIONInventors: Kyohei MATSUSHITA, Masahiro FUKASAKA, Takuya SHISHIDO, Daisuke ASARI, Katsuyuki OKUBO, Mitsuhiko HORI
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Patent number: 9962439Abstract: The present invention aims at providing an injectable vaccine composition that is safe, useful as a prophylactic or therapeutic agent for cancers or infectious diseases, and capable of inducing the systemic immune response safely and effectively.Type: GrantFiled: October 2, 2014Date of Patent: May 8, 2018Assignee: NITTO DENKO CORPORATIONInventors: Kyohei Matsushita, Masahiro Fukasaka, Arimichi Okazaki, Eiji Kiyotoh, Katsuyuki Okubo, Daisuke Asari, Mitsuhiko Hori
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Publication number: 20170246287Abstract: Disclosed is a vaccine composition for transdermal administration to induce cellular immunity, comprising an antigen, wherein Th1 cell ratio in a model animal for immunological evaluation that received the composition is 10% or more.Type: ApplicationFiled: October 28, 2016Publication date: August 31, 2017Applicant: NITTO DENKO CORPORATIONInventors: Takuya SHISHIDO, Katsuyuki OKUBO, Daisuke ASARI, Arimichi OKAZAKI, Yoshiki MAEDA, Kyohei MATSUSHITA, Wenjing LI, Mitsuhiko HORI, Haruo SUGIYAMA
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Publication number: 20170224812Abstract: The present invention aims to provide a humoral immunity induction-promoting composition and a vaccine pharmaceutical composition which can universally be used for inducing humoral immunity to various antigens and exert a high antibody production inducing effect. The present invention relates to a vaccine pharmaceutical composition for inducing humoral immunity containing an antigen and a humoral immunity induction promoter whose active ingredient is a thrombosis treatment drug.Type: ApplicationFiled: August 4, 2015Publication date: August 10, 2017Applicant: NITTO DENKO CORPORATIONInventors: Takuya SHISHIDO, Daisuke ASARI, Kyohei MATSUSHITA, Mitsuhiko HORI
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Publication number: 20170216429Abstract: The present invention aims to provide a composition for promoting humoral immunity induction and a vaccine pharmaceutical composition that can be universally used for various antigens in inducing humoral immunity to antigens, contain a Th2 reaction promoter, and exerts a high humoral immunity inducing effect. The present invention relates to a vaccine pharmaceutical composition containing an antigen for humoral immunity induction and at least one Th2 reaction promoter.Type: ApplicationFiled: August 4, 2015Publication date: August 3, 2017Applicant: NITTO DENKO CORPORATIONInventors: Takuya SHISHIDO, Daisuke ASARI, Kyohei MATSUSHITA, Mitsuhiko HORI
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Publication number: 20170216430Abstract: The present invention aims to provide a composition for promoting immunity induction and a vaccine pharmaceutical composition which are universally usable for inducing immunity to various antigens and capable of exerting a high immunity inducing effect. The present invention relates to a composition for promoting immunity induction containing at least one nuclear receptor ligand and also relates to a vaccine pharmaceutical composition for inducing immunity containing an antigen and a composition for promoting immunity induction that is at least one nuclear receptor ligand.Type: ApplicationFiled: August 4, 2015Publication date: August 3, 2017Applicant: NITTO DENKO CORPORATIONInventors: Takuya SHISHIDO, Daisuke ASARI, Kyohei MATSUSHITA, Mitsuhiko HORI
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Publication number: 20170216431Abstract: The present invention provides a vaccine pharmaceutical composition for transdermal administration which is safe, usable as a prophylactic or therapeutic agent for cancer or infectious diseases, and capable of safely and effectively inducing a systemic immune response.Type: ApplicationFiled: October 1, 2015Publication date: August 3, 2017Applicant: NITTO DENKO CORPORATIONInventors: Takuya SHISHIDO, Daisuke ASARI, Kyohei MATSUSHITA, Katsuyuki OKUBO, Mitsuhiko HORI
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Publication number: 20170007703Abstract: The present invention provides a skin penetration-accelerating composition that eliminates the need for forming a drug into a particle structure and dramatically improves the skin penetration properties of a drug without breaking the skin tissue. The present invention also provides a preparation for transdermal administration containing the skin penetration-accelerating composition and a patch preparation containing the skin penetration-accelerating composition. The present invention provides a skin penetration-accelerating composition containing a flavonoid compound and a surfactant and used for accelerating skin penetration of a drug.Type: ApplicationFiled: January 28, 2015Publication date: January 12, 2017Applicant: NITTO DENKO CORPORATIONInventors: Kyohei MATSUSHITA, Yoshiki MAEDA, Wenjing LI, Katsuyuki OKUBO, Mitsuhiko HORI
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Publication number: 20170000751Abstract: The present invention provides a skin penetration-accelerating composition that eliminates the need for forming a drug into a particle structure and dramatically improves the skin penetration properties of a drug without breaking the skin tissue. The present invention also provides a preparation for transdermal administration containing the skin penetration-accelerating composition and a patch preparation containing the skin penetration-accelerating composition. The present invention provides a skin penetration-accelerating composition containing a flavonoid compound and used for accelerating skin penetration of a drug.Type: ApplicationFiled: January 28, 2015Publication date: January 5, 2017Applicant: NITTO DENKO CORPORATIONInventors: Yoshiki MAEDA, Kyohei MATSUSHITA, Wenjing LI, Katsuyuki OKUBO, Mitsuhiko HORI
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Publication number: 20160287697Abstract: The present invention aims at providing an injectable vaccine composition that is safe, useful as a prophylactic or therapeutic agent for cancers or infectious diseases, and capable of inducing the systemic immune response safely and effectively.Type: ApplicationFiled: October 2, 2014Publication date: October 6, 2016Applicant: NITTO DENKO CORPORATIONInventors: Kyohei MATSUSHITA, Masahiro FUKASAKA, Arimichi OKAZAKI, Eiji KIYOTOH, Katsuyuki OKUBO, Daisuke ASARI, Mitsuhiko HORI
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Patent number: 9439872Abstract: The present invention aims to provide an oral film-form base and an oral film-form preparation which have a rapid dissolution profile in the mouth and sufficient film strength, give a good tactile impression when handled with fingers and favorable texture and taste in the mouth, and are administrable to those who have limitation in carbohydrate intake. The present invention relates to an oral film-form base including an edible polymer soluble in water and an organic solvent having a solubility parameter of 9.7 or higher, and particles of at least one compound selected from the group consisting of amino acid, dipeptide, and nucleotide, the particles of at least one compound selected from the group consisting of amino acid, dipeptide, and nucleotide being dispersed in the state of particles in the oral film-form base.Type: GrantFiled: July 30, 2015Date of Patent: September 13, 2016Assignee: NITTO DENKO CORPORATIONInventors: Kyohei Matsushita, Daisuke Asari, Takuya Shishido, Mitsuhiko Hori
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Publication number: 20160228540Abstract: The present invention provides a nasal mucosal vaccine composition which is safe, useful as a preventive or therapeutic agent for infectious diseases or cancers, and capable of inducing systemic immune responses and mucosal immune responses effectively.Type: ApplicationFiled: October 2, 2014Publication date: August 11, 2016Applicant: NITTO DENKO CORPORATIONInventors: Eiji KIYOTOH, Mitsuhiko HORI, Katsuyuki OKUBO, Daisuke ASARI, Arimichi OKAZAKI, Masahiro FUKASAKA, Kyohei MATSUSHITA
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Publication number: 20160213773Abstract: The present invention aims at providing a vaccine composition capable of being administered to an intraoral mucous membrane, ocular mucous membrane, ear mucous membrane, genital mucous membrane, pharyngeal mucous membrane, respiratory tract mucous membrane, bronchial mucous membrane, pulmonary mucous membrane, gastric mucous membrane, enteric mucous membrane, or rectal mucous membrane, that is safe, useful as a prophylactic or therapeutic agent for infectious diseases or cancers, and capable of effectively inducing the systemic immune response and mucosal immune response.Type: ApplicationFiled: October 2, 2014Publication date: July 28, 2016Applicant: NITTO DENKO CORPORATIONInventors: Masahiro FUKASAKA, Mitsuhiko HORI, Katsuyuki OKUBO, Daisuke ASARI, Arimichi OKAZAKI, Eiji KIYOTOH, Kyohei MATSUSHITA
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Publication number: 20160193327Abstract: The present invention aims at providing a mucosal vaccine composition that can be administered to an intraoral mucous membrane, ocular mucous membrane, ear mucous membrane, genital mucous membrane, pharyngeal mucous membrane, respiratory tract mucous membrane, bronchial mucous membrane, pulmonary mucous membrane, gastric mucous membrane, enteric mucous membrane, or rectal mucous membrane, that is useful as a prophylactic or therapeutic agent for infectious diseases or cancers, and is capable of safely and effectively inducing the systemic immune response and mucosal immune response.Type: ApplicationFiled: October 2, 2014Publication date: July 7, 2016Applicant: NITTO DENKO CORPORATIONInventors: Masahiro FUKASAKA, Mitsuhiko HORI, Katsuyuki OKUBO, Daisuke ASARI, Arimichi OKAZAKI, Eiji KIYOTOH, Kyohei MATSUSHITA
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Publication number: 20160058711Abstract: The present invention aims to provide an oral film-form base and an oral film-form preparation which have a rapid dissolution profile in the mouth and sufficient film strength, give a good tactile impression when handled with fingers and favorable texture and taste in the mouth, and are administrable to those who have limitation in carbohydrate intake. The present invention relates to an oral film-form base including an edible polymer soluble in water and an organic solvent having a solubility parameter of 9.7 or higher, and particles of at least one compound selected from the group consisting of amino acid, dipeptide, and nucleotide, the particles of at least one compound selected from the group consisting of amino acid, dipeptide, and nucleotide being dispersed in the state of particles in the oral film-form base.Type: ApplicationFiled: July 30, 2015Publication date: March 3, 2016Applicant: NITTO DENKO CORPORATIONInventors: Kyohei MATSUSHITA, Daisuke ASARI, Takuya SHISHIDO, Mitsuhiko HORI