Patents by Inventor Kyoichi Watanabe

Kyoichi Watanabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10100076
    Abstract: The disclosed invention is a composition for and a method of seating a Flaviviridae (including BVDV and HCV), Orthomyxoviridae (including Influenza A and B) or Paramyxoviridae (including RSV) infection, or conditions related to abnormal cellular proliferation, in a host, including animals, and especially humans, using a nucleoside of general formula (I)-(XXIII) or its pharmaceutically acceptable salt or prodrug. This invention also provides an effective process to quantify the viral load, and in particular BVDV, HCV or West Nile Virus load, in a host, using real-time polymerase chain reaction (“RT-PCR”). Additionally, the invention discloses probe molecules that can fluoresce proportionally to the amount of virus present in a sample.
    Type: Grant
    Filed: June 3, 2013
    Date of Patent: October 16, 2018
    Assignee: Gilead Pharmasset LLC
    Inventors: Lieven Stuyver, Kyoichi Watanabe
  • Patent number: 8785033
    Abstract: In an assembled battery including at least two unit cells provided within a supporter, each unit cell is a thin laminate cell packaged with a laminate, and each unit cell is covered by at least one resin. Thus, the assembled battery has a stable performance without structure breakdown or a fracture of the connection tab even when vibration is applied.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: July 22, 2014
    Assignee: Nissan Motor Co., Ltd.
    Inventors: Kyoichi Watanabe, Hideaki Horie, Hiroshi Sugawara
  • Patent number: 8663832
    Abstract: Disclosed is a cell with a power-generating element and an outer package. The power-generating element includes a unit cell layer including a first electrode, a second electrode and an electrolyte layer disposed between the first and second electrodes. In the first electrode, a first collector is provided with one of a positive electrode active material layer and a negative electrode active material layer. In the second electrode, a second collector is provided with the other one of the positive and negative electrode active material layers. The first and second collectors have thicknesses such that when a conductor from outside penetrates at least two cells and a short circuit is formed between two cells via the conductor, shorted portions of the first and second collectors are fused by the heat generated by the current before the temperature of the cells reaches a predetermined value so that the short circuit is blocked.
    Type: Grant
    Filed: August 12, 2008
    Date of Patent: March 4, 2014
    Assignee: Nissan Motor Co., Ltd.
    Inventors: Takaaki Abe, Kazuki Miyatake, Osamu Shimamura, Masakazu Kobayashi, Hideaki Horie, Kyoichi Watanabe, Yoshio Shimoida
  • Publication number: 20140057863
    Abstract: The disclosed invention is a composition for and a method of treating a Flaviviridae (including BVDV and HCV), Orthomyxoviridae (including Influenza A and B) or Paramyxoviridae (including RSV) infection, or conditions related to abnormal cellular proliferation, in a host, including animals, and especially humans, using a nucleoside of general formula (I)-(XXIII) or its pharmaceutically acceptable salt or prodrug. This invention also provides an effective process to quantify the viral load, and in particular BVDV, HCV or West Nile Virus load, in a host, using real-time polymerase chain reaction (“RT-PCR”). Additionally, the invention discloses probe molecules that can fluoresce proportionally to the amount of virus present in a sample.
    Type: Application
    Filed: June 3, 2013
    Publication date: February 27, 2014
    Applicant: GILEAD SCIENCES, INC.
    Inventors: Lieven Stuyver, Kyoichi Watanabe
  • Patent number: 8652220
    Abstract: A battery is provided with a plurality of unit cells each having a tab, a bus bar connecting the tab of one of the plurality of unit cells and the tab of another one of the plurality of unit cells, and a plurality of welding points disposed on a center of gravity of an area, in which the bus bar and the tab are overlapped, or a vicinity thereof, and at least one position of line segments, radiately extending from the center of gravity, or a vicinity thereof, such that the bus bar and the tab are connected to one another at the plurality of welding points.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: February 18, 2014
    Assignee: Nissan Motor Co., Inc.
    Inventors: Kyoichi Watanabe, Hideaki Horie, Takanori Ito, Takaaki Abe, Osamu Shimamura, Takamitsu Saitou, Hiroshi Sugawara
  • Publication number: 20130192058
    Abstract: A battery is provided with a plurality of unit cells each having a tab, a bus bar connecting the tab of one of the plurality of unit cells and the tab of another one of the plurality of unit cells, and a plurality of welding points disposed on a center of gravity of an area, in which the bus bar and the tab are overlapped, or a vicinity thereof, and at least one position of line segments, radiately extending from the center of gravity, or a vicinity thereof, such that the bus bar and the tab are connected to one another at the plurality of welding points.
    Type: Application
    Filed: March 11, 2013
    Publication date: August 1, 2013
    Applicant: Nissan Motor Co., Ltd.
    Inventors: Kyoichi WATANABE, Hideaki HORIE, Takanori ITO, Takaaki ABE, Osamu SHIMAMURA, Takamitsu SAITOU, Hiroshi SUGAWARA
  • Patent number: 8465872
    Abstract: The positive electrode active material sintered body for a battery of the present invention is a positive electrode active material sintered body for a battery satisfying the following requirements (I) to (VII): (I) fine particles in a positive electrode active material are sintered to constitute the sintered body; (II) a peak pore diameter which provides a maximum differential pore volume value in a pore diameter range of 0.01 to 10 ?m in a pore distribution is 0.3 to 5 ?m; (III) a total pore volume is 0.1 to 1 cc/g; (IV) an average particle diameter is not less than the peak pore diameter and not more than 20 ?m; (V) any peak, which provides a differential pore volume value of not less than 10% of the maximum differential pore volume value, is not present on a smaller pore diameter side than the peak pore diameter in the pore distribution; (VI) a BET specific surface area is 1 to 6 m2/g; and (VII) a full width at half maximum of a strongest X-ray diffraction peak is 0.13 to 0.2.
    Type: Grant
    Filed: April 7, 2008
    Date of Patent: June 18, 2013
    Assignees: Kao Corporation, Nissan Motor Co., Ltd.
    Inventors: Ryuichi Akagi, Kenichi Nishimura, Yasuhisa Fukumoto, Kyoichi Watanabe, Tamaki Miura, Takamitsu Saito
  • Patent number: 8444875
    Abstract: The burned composite metal oxide of the present invention is a burned composite metal oxide which is porous and particulate and which is obtained by subjecting a slurry comprising at least one metal oxide (a), at least one metal compound (b) and a solvent to spray granulation to obtain granules, and burning the granules, the metal oxide (a) selected from the group consisting of a transition metal oxide and an oxide of a metal belonging to 3B, 4B and 5B of a periodic table, the metal compound (b) selected from the group consisting of an alkali metal compound and an alkali earth metal compound, wherein the metal oxide (a) and the metal compound (b) are sparingly soluble in the solvent; the burning is conducted after a heat-maintaining step of heating the granules obtained by the spray granulation at a temperature in a range of ±200° C.
    Type: Grant
    Filed: December 3, 2008
    Date of Patent: May 21, 2013
    Assignee: Kao Corporation
    Inventors: Kazuo Oki, Minoru Sawai, Hiroaki Kitayama, Takamitsu Saito, Tamaki Miura, Kyoichi Watanabe
  • Patent number: 8426064
    Abstract: The present invention provides a composite material for positive electrodes of lithium batteries, which provides a lithium battery having excellent high rate electrical discharge characteristics, has a sufficiently secured diffusion passage for Li, and has high conductivity, a process for producing the same, as well as a positive electrode and a battery using the composite material for positive electrodes of lithium batteries. The present invention relates to a composite material for positive electrodes of lithium batteries, comprising composite particles containing positive electrode active material particles and fibrous carbons, wherein the composite particles have a form in which the positive electrode active material particles are supported by the fibrous carbons.
    Type: Grant
    Filed: December 3, 2008
    Date of Patent: April 23, 2013
    Assignee: Kao Corporation
    Inventors: Kazuo Oki, Minoru Sawai, Hiroaki Kitayama, Takamitsu Saito, Tamaki Miura, Kyoichi Watanabe
  • Patent number: 8420251
    Abstract: A battery is provided with a plurality of unit cells each having a tab, a bus bar connecting the tab of one of the plurality of unit cells and the tab of another one of the plurality of unit cells, and a plurality of welding points disposed on a center of gravity of an area, in which the bus bar and the tab are overlapped, or a vicinity thereof, and at least one position of line segments, radiately extending from the center of gravity, or a vicinity thereof, such that the bus bar and the tab are connected to one another at the plurality of welding points.
    Type: Grant
    Filed: February 5, 2003
    Date of Patent: April 16, 2013
    Assignee: Nissan Motor Co., Ltd.
    Inventors: Kyoichi Watanabe, Hideaki Horie, Takanori Ito, Takaaki Abe, Osamu Shimamura, Takamitsu Saitou, Hiroshi Sugawara
  • Patent number: 8415049
    Abstract: The present invention provides a bipolar battery made by using a polymer gel electrolyte or a liquid electrolyte in an electrolyte layer, which is highly reliable and prevents liquid junction (short circuit) caused by leak out of an electrolyte solution from the electrolyte part. The present invention provides a bipolar battery laminated, in series, with a plurality pieces of bipolar electrodes which is formed with a positive electrode on one surface of a collector, and a negative electrode on the other surface, so as to sandwich an electrolyte layer, characterized by being provided with a separator which retains the electrolyte later, and a seal resin which is formed and arranged at the outer circumference part of a part of the separator where the electrolyte is retained.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: April 9, 2013
    Assignee: Nissan Motor Co., Ltd.
    Inventors: Osamu Shimamura, Kenji Hosaka, Kyoichi Watanabe, Takaaki Abe, Takuya Kinoshita, Hideaki Horie, Hajime Sato, Ryouichi Senbokuya
  • Patent number: 8304103
    Abstract: A battery structure for improving a heat dissipating property and a vibration absorbing performance. The battery structure comprises a plurality of unit cell layers, each formed by alternately stacking a cathode active material layer formed on a surface of one collector, a separator for retaining an electrolyte and an anode active material layer formed on a surface of another collector. The battery structure also comprises a heat dissipating member disposed between at least one unit cell layer and another unit cell layer.
    Type: Grant
    Filed: May 17, 2007
    Date of Patent: November 6, 2012
    Assignee: Nissan Motor Co., Ltd.
    Inventors: Kyoichi Watanabe, Hajime Sato, Kenji Hosaka, Hideaki Horie
  • Publication number: 20120202766
    Abstract: The present invention is directed to a method and composition of treating or preventing viral infections, in particular, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts, comprising the administration of N.sup.4-acyl-2?,3?-dideoxy-5-fluorocytidine or N.sup.4-acyl-2?,3?-didehyd-ro-2?,3?-dideoxy-5-fluorocytidine, and pharmaceutically acceptable salts, prodrugs, and other derivatives thereof.
    Type: Application
    Filed: February 13, 2012
    Publication date: August 9, 2012
    Applicant: Pharmasset, Inc.
    Inventors: Michael J. Otto, Junxing Shi, Kyoichi A. Watanabe
  • Patent number: 8124276
    Abstract: A bipolar battery includes: a bipolar electrode composed, by forming a positive electrode active material layer 12 an one surface of a current collector and forming a negative electrode active material layer 13 on the other surface; and a separator 14 composed to be stacked alternately with the bipolar electrode, wherein, in a single cell layer 15 composed by including the positive electrode active material layer 12, the separator 14 and the negative electrode active material layer 13, which are adjacent to one another, a thickness of the separator 14 is 0.68 times or more to less than 1.0 times a thickness of the positive electrode active material layer 12, and is 0.68 times or more to less than 1.0 times a thickness of the negative electrode active material layer 13.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: February 28, 2012
    Assignee: Nissan Motor Co., Ltd.
    Inventors: Kyoichi Watanabe, Takaaki Abe, Takamitsu Saito, Osamu Shimamura, Kenji Hosaka, Hajime Sato, Hideaki Horie
  • Patent number: 8114997
    Abstract: The present invention is directed to a method and composition of treating or preventing viral infections, in particular, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts, comprising the administration of N.sup.4-acyl-2?,3?-dideoxy-5-fluorocytidine or N.sup.4-acyl-2?,3?-didehyd-ro-2?,3?-dideoxy-5-fluorocytidine, and pharmaceutically acceptable salts, prodrugs, and other derivatives thereof.
    Type: Grant
    Filed: January 4, 2008
    Date of Patent: February 14, 2012
    Assignee: Pharmasset, Inc.
    Inventors: Michael J. Otto, Junxing Shi, Kyoichi A. Watanabe
  • Publication number: 20120005882
    Abstract: The present invention provides a bipolar battery made by using a polymer gel electrolyte or a liquid electrolyte in an electrolyte layer, which is highly reliable and prevents liquid junction (short circuit) caused by leak out of an electrolyte solution from the electrolyte part. The present invention provides a bipolar battery laminated, in series, with a plurality pieces of bipolar electrodes which is formed with a positive electrode on one surface of a collector, and a negative electrode on the other surface, so as to sandwich an electrolyte layer, characterized by being provided with a separator which retains the electrolyte later, and a seal resin which is formed and arranged at the outer circumference part of a part of the separator where the electrolyte is retained.
    Type: Application
    Filed: September 22, 2011
    Publication date: January 12, 2012
    Inventors: Osamu SHIMAMURA, Kenji HOSAKA, Kyoichi WATANABE, Takaaki ABE, Takuya KINOSHITA, Hideaki HORIE, Hajime SATO, Ryouichi SENBOKUYA
  • Patent number: 8093380
    Abstract: The disclosed invention is a bicyclo[4.2.1]nonane and its pharmaceutically acceptable salt or prodrug, and its composition and method of use to treat Flaviviridae (Hepacivirus, Flavivirus, and Pestivirus) infections in a host, including animals, and especially humans.
    Type: Grant
    Filed: August 1, 2003
    Date of Patent: January 10, 2012
    Assignee: Pharmasset, Inc.
    Inventors: Peiyuan Wang, Lieven J. Stuyver, Kyoichi A. Watanabe, Abdalla Hassan, Byoung-Kwon Chun, Laurent Hollecker
  • Patent number: 8076021
    Abstract: The present invention provides a bipolar battery made by using a polymer gel electrolyte or a liquid electrolyte in an electrolyte layer, which is highly reliable and prevents liquid junction (short circuit) caused by leak out of an electrolyte solution from the electrolyte part. The present invention provides a bipolar battery laminated, in series, with a plurality pieces of bipolar electrodes which is formed with a positive electrode on one surface of a collector, and a negative electrode on the other surface, so as to sandwich an electrolyte layer, characterized by being provided with a separator which retains the electrolyte later, and a seal resin which is formed and arranged at the outer circumference part of a part of the separator where the electrolyte is retained.
    Type: Grant
    Filed: December 9, 2005
    Date of Patent: December 13, 2011
    Assignee: Nissan Motor Co., Ltd.
    Inventors: Osamu Shimamura, Kenji Hosaka, Kyoichi Watanabe, Takaaki Abe, Takuya Kinoshita, Hideaki Horie, Hajime Sato, Ryouichi Senbokuya
  • Publication number: 20110269707
    Abstract: The disclosed invention is a composition for and a method of treating a Flaviviridae (including BVDV and HCV), Orthomyxoviridae (including Influenza A and B) or Paramyxoviridae (including RSV) infection, or conditions related to abnormal cellular proliferation, in a host, including animals, and especially humans, using a nucleoside of general formula (I)-(XXIII) or its pharmaceutically acceptable salt or prodrug. This invention also provides an effective process to quantify the viral load, and in particular BVDV, HCV or West Nile Virus load, in a host, using real-time polymerase chain reaction (“RT-PCR”). Additionally, the invention discloses probe molecules that can fluoresce proportionally to the amount of virus present in a sample.
    Type: Application
    Filed: August 5, 2010
    Publication date: November 3, 2011
    Inventors: Lieven Stuyver, Kyoichi Watanabe
  • Patent number: RE42015
    Abstract: The present invention is directed to a compound, method and composition of treating or preventing viral infections, in particular, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts, comprising the administration of N4-acylcytosine-1,3-dioxolane and pharmaceutically acceptable salts, prodrugs, and other derivatives thereof.
    Type: Grant
    Filed: June 21, 2007
    Date of Patent: December 28, 2010
    Assignee: Pharmasset, Inc.
    Inventors: Kyoichi A. Watanabe, Junxing Shi, Michael J. Otto