Abstract: An ophthalmologic photographing apparatus includes an optical system, a pedestal, an auxiliary lens configured to be able to be inserted into and retracted from the optical system, a focusing lens, a focusing lens driving unit configured to move the focusing lens along an optical axis, a pedestal position detection unit configured to detect that the pedestal is away from the subject's eye by a predetermined distance, an auxiliary lens insertion detection unit configured to detect that the auxiliary lens is inserted into the optical system, a storage unit configured to store a position of the focusing lens, and a control unit configured to cause the focusing lens driving unit to move the focusing lens to a predetermined position stored in the storage unit based on outputs from the pedestal position detection unit and the auxiliary lens insertion detection unit.

Abstract: When the fundus camera is positioned on the same side as the subject's eye relative to an appropriate position (front-focus state), the positioning index light source turned on in blue produces most-focused positioning index images. The positioning index light sources become more blurred in order of green and red. When the camera is positioned on the opposite side of the subject's eye relative to the appropriate position (rear-focus state), the positioning index light source turned on in red produces most-focused images. The positioning index light sources become more blurred in order of green and blue. Based on a degree of the blur of the individual positioning index images in red, green, and blue reflected by the cornea of the subject's eye, the calculation unit calculates whether to move the camera body closer to or farther away from the subject's eye and allows the display unit to display the information.

Abstract: The invention intends to find out an in-vitro bioassay system capable of ensuring qualities of yokukansan to a higher degree, and provides a bioassay method for yokukansan, comprising competitively reacting labeled ligand and a test sample containing yokukansan with cells or cell membranes expressing serotonin 1A receptors, and measuring binding activity of yokukansan from the amount of the labeled ligand bound, and a bioassay method for yokukansan, comprising reacting labeled GTP and a test sample containing yokukansan with cells or cell membranes expressing serotonin 1A receptors, and measuring receptor-agonist activity of yokukansan from the amount of the labeled GTP bound.

Abstract: A fundus camera that obtains focus evaluation values by scanning, in which a focusing lens moves a predetermined distance according to a photographing mode before the focusing lens starts scanning for obtaining focus evaluation values.

Abstract: A fundus camera that obtains focus evaluation values by scanning, in which a focusing lens moves a predetermined distance according to a photographing mode before the focusing lens starts scanning for obtaining focus evaluation values.

Abstract: An ophthalmologic photographing apparatus includes an optical system, a pedestal, an auxiliary lens configured to be able to be inserted into and retracted from the optical system, a focusing lens, a focusing lens driving unit configured to move the focusing lens along an optical axis, a pedestal position detection unit configured to detect that the pedestal is away from the subject's eye by a predetermined distance, an auxiliary lens insertion detection unit configured to detect that the auxiliary lens is inserted into the optical system, a storage unit configured to store a position of the focusing lens, and a control unit configured to cause the focusing lens driving unit to move the focusing lens to a predetermined position stored in the storage unit based on outputs from the pedestal position detection unit and the auxiliary lens insertion detection unit.

Abstract: A fundus camera that obtains focus evaluation values by scanning, in which a focusing lens moves a predetermined distance according to a photographing mode before the focusing lens starts scanning for obtaining focus evaluation values.

Abstract: An ophthalmologic photographing apparatus includes an optical system, a pedestal, an auxiliary lens configured to be able to be inserted into and retracted from the optical system, a focusing lens, a focusing lens driving unit configured to move the focusing lens along an optical axis, a pedestal position detection unit configured to detect that the pedestal is away from the subject's eye by a predetermined distance, an auxiliary lens insertion detection unit configured to detect that the auxiliary lens is inserted into the optical system, a storage unit configured to store a position of the focusing lens, and a control unit configured to cause the focusing lens driving unit to move the focusing lens to a predetermined position stored in the storage unit based on outputs from the pedestal position detection unit and the auxiliary lens insertion detection unit.

Abstract: A fundus camera includes an observation photographing unit having a focusing lens to perform focusing of an imaging unit on a fundus of a subject's eye, a lens driving unit configured to drive the focusing lens in an optical axis direction, and a focusing control unit configured to calculate a focusing evaluation value based on image information of a predetermined area of a fundus image captured by the observation photographing unit, and drive the focusing lens based on the focusing evaluation value, thereby performing focusing, wherein the focusing control unit moves the focusing lens from a previous photographing position of the focusing lens by a predetermined moving amount, and then performs the focusing.

Abstract: An ophthalmologic photographing apparatus includes an optical system, a pedestal, an auxiliary lens configured to be able to be inserted into and retracted from the optical system, a focusing lens, a focusing lens driving unit configured to move the focusing lens along an optical axis, a pedestal position detection unit configured to detect that the pedestal is away from the subject's eye by a predetermined distance, an auxiliary lens insertion detection unit configured to detect that the auxiliary lens is inserted into the optical system, a storage unit configured to store a position of the focusing lens, and a control unit configured to cause the focusing lens driving unit to move the focusing lens to a predetermined position stored in the storage unit based on outputs from the pedestal position detection unit and the auxiliary lens insertion detection unit.

Abstract: When the fundus camera is positioned on the same side as the subject's eye relative to an appropriate position (front-focus state), the positioning index light source turned on in blue produces most-focused positioning index images. The positioning index light sources become more blurred in order of green and red. When the camera is positioned on the opposite side of the subject's eye relative to the appropriate position (rear-focus state), the positioning index light source turned on in red produces most-focused images. The positioning index light sources become more blurred in order of green and blue. Based on a degree of the blur of the individual positioning index images in red, green, and blue reflected by the cornea of the subject's eye, the calculation unit calculates whether to move the camera body closer to or farther away from the subject's eye and allows the display unit to display the information.

Abstract: A fundus camera that obtains focus evaluation values by scanning, in which a focusing lens moves a predetermined distance according to a photographing mode before the focusing lens starts scanning for obtaining focus evaluation values.

Abstract: A method for manufacturing alloy powders based on titanium, zirconium and hafnium alloyed with the elements Ni, Cu, Ta, W, Re, Os, and Ir is described in which an oxide of Ti and Zr and Hf is mixed with a metal powder of the elements named and with a reducing agent, and wherein this mixture is heated in a furnace, optionally under a argonate atmosphere or, optionally under hydrogen atmosphere until the reducing reaction begins, the reaction product is leached and then washed and dried, wherein the oxide used has an average grain size of 0.5 to 20 ?m, a specific surface area according to BET of 0.5 20 m2/g and a minimum content of 94 wet.-%. An easy to produce powder, in particular in relation to the ignition point and burning time, is produced.

Abstract: The invention intends to find out an in-vitro bioassay system capable of ensuring qualities of yokukansan to a higher degree, and provides a bioassay method for yokukansan, comprising competitively reacting labeled ligand and a test sample containing yokukansan with cells or cell membranes expressing serotonin 1A receptors, and measuring binding activity of yokukansan from the amount of the labeled ligand bound, and a bioassay method for yokukansan, comprising reacting labeled GTP and a test sample containing yokukansan with cells or cell membranes expressing serotonin 1A receptors, and measuring receptor-agonist activity of yokukansan from the amount of the labeled GTP bound.

Abstract: A fundus camera includes an observation photographing unit having a focusing lens to perform focusing of an imaging unit on a fundus of a subject's eye, a lens driving unit configured to drive the focusing lens in an optical axis direction, and a focusing control unit configured to calculate a focusing evaluation value based on image information of a predetermined area of a fundus image captured by the observation photographing unit, and drive the focusing lens based on the focusing evaluation value, thereby performing focusing, wherein the focusing control unit moves the focusing lens from a previous photographing position of the focusing lens by a predetermined moving amount, and then performs the focusing.

Abstract: An area having a diameter in which a peripheral area of an eye fundus image is covered with a mask is displayed on a monitor. When a region which may be abnormal is found in the vicinity of a boundary between the mask and the eye fundus image during image viewing, the display area enlarging means is operated. Then, an aperture area of the mask is enlarged to expand a display area of the eye fundus image, so the eye fundus image including some flare is displayed on a wide area. Therefore, an abnormal state of the region can be recognized.

Abstract: In a case of right and left eye fundus image sensing in a mass health examination, the alignment of an anterior segment of an eye to be examined is performed first (S101). When the alignment of the anterior segment of eye is completed, image sensing light intensity is set (S102). The alignment of a fundus segment of the eye to be examined is performed (S103). Furthermore, an image of the fundus of the eye to be examined is sensed by a sensing switch being pushed after the completion of focus adjustment (S104). Next, an optical base unit is moved so that the image sensing of another eye can be performed (S105). A left or right eye detection unit detects that an eye for image sensing is changed with the move of the optical base unit. When the eye for image sensing is changed, an image sensing light intensity setting unit sets image sensing light intensity by adding a predetermined amount, or changing the sets image sensing light intensity according to a diameter of a pupil (S106).

Abstract: To determine the presence or absence of an aperture mask in a funduscopic image output by a fundus camera, and to combine the funduscopic image with an aperture mask image formed in an aperture mask-forming section so as to correspond to a determination result. When an aperture mask determination section 34 determines the absence of the aperture mask image in the funduscopic image and the necessity of the addition, the aperture mask-forming section 35 forms a necessary mask, and an aperture mask combine section 36 combines the funduscopic image with the aperture mask image.

Abstract: In a case of right and left eye fundus image sensing in a mass health examination, the alignment of an anterior segment of an eye to be examined is performed first (S101). When the alignment of the anterior segment of eye is completed, image sensing light intensity is set (S102). The alignment of a fundus segment of the eye to be examined is performed (S103). Furthermore, an image of the fundus of the eye to be examined is sensed by a sensing switch being pushed after the completion of focus adjustment (S104). Next, an optical base unit is moved so that the image sensing of another eye can be performed (S105). A left or right eye detection unit detects that an eye for image sensing is changed with the move of the optical base unit. When the eye for image sensing is changed, an image sensing light intensity setting unit sets image sensing light intensity by adding a predetermined amount, or changing the sets image sensing light intensity according to a diameter of a pupil (S106).

Abstract: An area having a diameter in which a peripheral area of an eye fundus image is covered with a mask is displayed on a monitor. When a region which may be abnormal is found in the vicinity of a boundary between the mask and the eye fundus image during image viewing, the display area enlarging means is operated. Then, an aperture area of the mask is enlarged to expand a display area of the eye fundus image, so the eye fundus image including some flare is displayed on a wide area. Therefore, an abnormal state of the region can be recognized.