Patents by Inventor Kyoko Nakagawa-Goto

Kyoko Nakagawa-Goto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sesquiterpene derivatives and their use in inflammation or cancer treatment
    Patent number: 10238631
    Abstract: A new class of sesquiterpene derivative useful for treating cancerous and inflammatory diseases are disclosed. These deoxyelephantopin derivatives are effective in suppressing proliferation, migration, mobility, invasion, growth, and/or metastasis of cancer cells in a patient, or useful for enhancing an anti-proliferative effect of another anti-cancer drug on cancer cells when treating a patient, or for sensitizing and/or enhancing an anti-cancer effect of a gluthathione synthesis blocker on inhibition of triple negative breast cancer cell activity, or for treatment and/or prophylaxis of lipopolysaccharide-stimulated inflammatory response in a patient, or for all of the above. Also disclosed are methods of preparing the deoxyelephantopin derivatives.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: March 26, 2019
    Assignee: Academia Sinica
    Inventors: Lie-Fen Shyur, Kuo-Hsiung Lee, Kyoko Nakagawa-Goto, Jia-Hua Feng, Jo-Yu Chen, Wai-Leng Lee, Yu-Ting Cheng, Jing-Ying Huang
  • NOVEL SESQUITERPENE DERIVATIVES AND THEIR USE IN INFLAMMATION OR CANCER TREATMENT
    Publication number: 20170182001
    Abstract: A new class of sesquiterpene derivative useful for treating cancerous and inflammatory diseases are disclosed. These deoxyelephantopin derivatives are effective in suppressing proliferation, migration, mobility, invasion, growth, and/or metastasis of cancer cells in a patient, or useful for enhancing an anti-proliferative effect of another anti-cancer drug on cancer cells when treating a patient, or for sensitizing and/or enhancing an anti-cancer effect of a gluthathione synthesis blocker on inhibition of triple negative breast cancer cell activity, or for treatment and/or prophylaxis of lipopolysaccharide-stimulated inflammatory response in a patient, or for all of the above. Also disclosed are methods of preparing the deoxyelephantopin derivatives.
    Type: Application
    Filed: June 5, 2015
    Publication date: June 29, 2017
    Inventors: Lie-Fen SHYUR, Kuo-Hsiung LEE, Kyoko NAKAGAWA-GOTO, Jia-Hua FENG, Jo-Yu CHEN, Wai-Leng LEE, Yu-Ting CHENG, Jing-Ying HUANG
  • Desmosdumotins, the method for preparing the same and use as anti-tumor or anti-AIDS agents
    Patent number: 7834216
    Abstract: This invention discloses the method for preparing desmosdumotin C, the series of desmosdumotin C derivatives and their manufactures, and the total synthesis of desmosdumotin B. The invention also discloses uses of the derivatives and pharmaceutical compositions containing the same in preparation of medicines for treatment of tumor or AIDS.
    Type: Grant
    Filed: December 28, 2005
    Date of Patent: November 16, 2010
    Inventors: Jiuhong Wu, Kyoko Nakagawa-Goto, Xihong Wang, Ning Shi
  • Desmosdumotins, the Method for Preparing the Same and Use as Anti-Tumor or Anti-AIDS Agents
    Publication number: 20090233998
    Abstract: This invention discloses the method for preparing desmosdumotin C, the series of desmosdumotin C derivatives and their manufactures, and the total synthesis of desmosdumotin B. The invention also discloses uses of the derivatives and pharmaceutical compositions containing the same in preparation of medicines for treatment of tumor or AIDS.
    Type: Application
    Filed: December 28, 2005
    Publication date: September 17, 2009
    Inventors: Jiuhong Wu, Kyoko Nakagawa-Goto, Xihong Wang, Ning Shi