Abstract: Systems and methods for receiving a blurred two-dimensional image captured using an optic system. The blurred two-dimensional image is deconvoluted using a point spread function for the optic system. A stack of non-blurred two-dimensional images is generated, each non-blurred image having a z-axis coordinate. A three-dimensional image is constructed from the stack of two-dimensional images.

Abstract: Systems and methods of communicating image data over a communication network. The systems and methods include receiving, by a computing device, image data and compressing the image data, by the computing device, using at least one of a blurring function and a down sampling function to form a compressed image. The computing device can generate intensity data and edge data. The computing device can aggregate the compressed image data, the intensity data and the edge data into a single encoded file, and transmit by the computing device, the single encoded file over the communication network.

Abstract: One aspect of the present invention relates to a method of controlling axon or dendrite development in a neuronal cell population. This method involves providing a neuronal cell population and contacting the neuronal cell population with a modulator of R-type Ca2+ channel expression or activity in controlling the neuronal cell population to induce either axon or dendrite development. Another aspect of the present invention relates to a method of treating neuronal injury in a subject. This method involves selecting a subject with neuronal injury mediated by R-type Ca2+ channel expression or activity and administering to the selected subject an inhibitor of R-type Ca2+ channel expression or activity to induce neuronal axon development under conditions effective to treat the neuronal injury in the subject. Yet another aspect of the present invention relates to a method of screening for agents that modulate R-type Ca2+ channel expression or activity.