Patents by Inventor Kyoung-Chan Kwon

Kyoung-Chan Kwon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESSES FOR PREPARING (3R,4R)-1-BENZYL-N,4-DIMETHYLPIPERIDIN-3-AMINE OR A SALT THEREOF AND PROCESSES FOR PREPARING TOFACITINIB USING THE SAME
    Publication number: 20220144774
    Abstract: Provided are a novel process for preparing (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine or a salt thereof, which is an intermediate useful for the preparation of tofacitinib, an intermediate used in the process, i.e., isopropanol solvate of methyl ((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)carbamate dibenzoyl-L-tartrate, an intermediate, having excellent stability, useful for the preparation of tofacitinib, i.e., (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine acetate, and a process for preparing tofacitinib or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 3, 2020
    Publication date: May 12, 2022
    Applicant: YUHAN CORPORATION
    Inventors: Sang-Ho OH, Doo-Byung LEE, Kyoung-Chan KWON, Sang-Won KIM, Hyo-Ick HWANG, Kyeong-Sill LEE, Ik-Su JO, Ji-Hye CHOI, Sung-Hee CHO, Su-Young LEE
  • Process for preparation of 2-methyl-2?-phenylpropionic acid derivatives and novel intermediate compounds
    Patent number: 8633223
    Abstract: The present invention relates to a process for preparing 2-methyl-2?-phenylpropionic acid derivatives showing antihistamine activity in more simplified way, intermediate compounds and their preparation processes used therefor. According to the present invention, pharmaceutically useful 2-methyl-2?-phenylpropionic acid derivatives can be prepared with high yield and purity on industrial scale.
    Type: Grant
    Filed: December 26, 2012
    Date of Patent: January 21, 2014
    Assignee: Yuhan Corporation
    Inventors: Chun-Ho Lee, Ja-Heouk Khoo, Kyoung-Chan Kwon, Hyun Ju
  • Process for preparation of 2-methyl-2?-phenylpropionic acid derivatives and novel intermediate compounds
    Patent number: 8487106
    Abstract: The present invention relates to a process for preparing 2-methyl-2?-phenylpropionic acid derivatives showing antihistamine activity in more simplified way, intermediate compounds and their preparation processes used therefore. According to the present invention, pharmaceutically useful 2-methyl-2?-phenylpropionic acid derivatives can be prepared with high yield and purity on industrial scale.
    Type: Grant
    Filed: December 26, 2012
    Date of Patent: July 16, 2013
    Assignee: Yuhan Corporation
    Inventors: Chun-Ho Lee, Ja-Heouk Khoo, Kyoung-Chan Kwon, Hyun Ju
  • Process for preparation of 2-methyl-2? phenylpropionic acid derivatives and novel intermediate compounds
    Patent number: 8367704
    Abstract: The present invention relates to a process for preparing 2-methyl-2?-phenylpropionic acid derivatives showing antihistamine activity in more simplified way, intermediate compounds and their preparation processes used therefor. According to the present invention, pharmaceutically useful 2-methyl-2?-phenylpropionic acid derivatives can be prepared with high yield and purity on industrial scale.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: February 5, 2013
    Assignee: Yuhan Corporation
    Inventors: Chun-Ho Lee, Ja-Heouk Khoo, Kyoung-Chan Kwon, Hyun Ju
  • PROCESS FOR THE PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS
    Publication number: 20110009636
    Abstract: The present invention relates to a process for preparing 2-methyl-2?-phenylpropionic acid derivatives showing antihistamine activity in more simplified way, intermediate compounds and their preparation processes used therefor. According to the present invention, pharmaceutically useful 2-methyl-2?-phenylpropionic acid derivatives can be prepared with high yield and purity on industrial scale.
    Type: Application
    Filed: February 12, 2009
    Publication date: January 13, 2011
    Inventors: Chun-Ho Lee, Ja-Heouk Khoo, Kyoung-Chan Kwon, Hyun Ju
  • Process for preparing terbinafine and HCI salt thereof
    Patent number: 6689913
    Abstract: Provided is a process for preparing terbinafine or its HCl salt comprising: reacting a furan derivative with a base to form a second compound; performing a reductive alkylation of the second compound obtained in the step with N-methyl-1-naphthalenemethylamine or its HCl salt to form a third compound; and purifying the third compound.
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: February 10, 2004
    Assignee: Yuhan Corporation
    Inventors: Tai-Au Lee, Kyu-Jung Wang, Hong-Bae Kim, Kyoung-Chan Kwon, Chang-Hoe Ku
  • Process for preparing terbinafine and HCI salt thereof
    Publication number: 20030130530
    Abstract: Provided are a process for preparing terbinafine or its HCl salt, which comprises: (a) reacting a furan derivative with a base; (b) performing a reductive alkylation of the resulting compound obtained in the step (a) with N-methyl-1-naphthalenemethylamine or its HCl salt; and (c) purifying the resulting compound obtained in the step (b).
    Type: Application
    Filed: December 27, 2002
    Publication date: July 10, 2003
    Inventors: Tai-Au Lee, Kyu-Jung Wang, Hong-Bae Kim, Kyoung-Chan Kwon, Chang-Hoe Ku