Patents by Inventor Kyoung Gyun LEE
Kyoung Gyun LEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12229951Abstract: Provided are a device for a digital assay of targets according to an exemplary embodiment of the present disclosure and a method using the same. The digital assay method of targets according to the exemplary embodiment of the present disclosure includes acquiring an image for a plurality of microdroplets, predicting at least one region based on the image for the plurality of microdroplets using an artificial neural network-based prediction model configured to segment at least one region among positive microdroplets, negative microdroplets, and atypical microdroplets, with the image for the plurality of microdroplets as an input, determining a number for the plurality of microdroplets based on the at least one region, and providing quantitative data of targets based on the number for the plurality of microdroplets.Type: GrantFiled: December 20, 2021Date of Patent: February 18, 2025Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Kyoung Gyun Lee, Sung Gap Im, Seok Jae Lee, Youn Seong Song, Yoo Min Park, Nam Ho Bae
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Publication number: 20230417667Abstract: Methods, systems, and apparatus, for a sensor-chip device for performing analysis on target substances. In one aspect, the sensor-chip assembly includes a chip body including a substrate, at least one metal layer formed on the substrate, and nanoholes formed in the metal layer, a base having an accommodating portion for accommodating the chip body, and a fixing member fixing the chip body accommodated in the accommodating portion by being coupled to the base.Type: ApplicationFiled: November 1, 2021Publication date: December 28, 2023Inventors: Hakho Lee, Hyungsoon Im, Nam Ho Bae, Seok Jae Lee, Kyoung Gyun Lee, Kwang Hee Kim, Kil Sun Roh
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Publication number: 20230256429Abstract: A modular fluidic chip includes a body configured to have at least one flow channel formed in an inside thereof and be connected to another modular fluidic chip to allow the at least one flow channel to communicate with a flow channel provided in the other modular fluidic chip. A fluidic chip capable of performing one function is formed in the form of a module, whereby a fluidic flow system of various structures can be implemented without restriction in shape or size by connecting a plurality of fluidic chips capable of performing different functions as necessary. Through this, various and accurate experimental data can be obtained, and when a specific portion is deformed or damaged, only the fluidic chip corresponding thereto can be replaced, thereby reducing manufacture and maintenance costs.Type: ApplicationFiled: April 20, 2023Publication date: August 17, 2023Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Seok Jae LEE, Moon Keun LEE, Nam Ho BAE, Tae Jae LEE, Kyoung Gyun LEE, Yoo Min PARK
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Patent number: 11666902Abstract: A modular fluidic chip includes a body configured to have at least one flow channel formed in an inside thereof and be connected to another modular fluidic chip to allow the at least one flow channel to communicate with a flow channel provided in the other modular fluidic chip. A fluidic chip capable of performing one function is formed in the form of a module, whereby a fluidic flow system of various structures can be implemented without restriction in shape or size by connecting a plurality of fluidic chips capable of performing different functions as necessary. Through this, various and accurate experimental data can be obtained, and when a specific portion is deformed or damaged, only the fluidic chip corresponding thereto can be replaced, thereby reducing manufacture and maintenance costs.Type: GrantFiled: July 25, 2019Date of Patent: June 6, 2023Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Seok Jae Lee, Moon Keun Lee, Nam Ho Bae, Tae Jae Lee, Kyoung Gyun Lee, Yoo Min Park
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Publication number: 20230153993Abstract: A method for providing quantitative information for targets and a device using the same according to an exemplary embodiment of the present disclosure are provided. A quantitative information providing method for targets according to the exemplary embodiment of the present disclosure includes flowing a plurality of microdroplets into a chamber or a channel including a detection region acquiring a single layer of microdroplets in which the plurality of microdroplets is present as a single layer, and providing quantitative data of targets based on the single layer image of the microdroplets, and the detection region has a height which is one time to about two times of a diameter of the plurality of microdroplets and is defined as a region in which the plurality of microdroplets is dispersed in a plurality of columns to fill the detection region.Type: ApplicationFiled: December 20, 2021Publication date: May 18, 2023Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Kyoung Gyun LEE, Seok Jae LEE, Nam Ho BAE, Dong Gee RHO, Tae Jae LEE, Moon Keun LEE, Yoo Min PARK
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Publication number: 20230153992Abstract: Provided are a device for a digital assay of targets according to an exemplary embodiment of the present disclosure and a method using the same. The digital assay method of targets according to the exemplary embodiment of the present disclosure includes acquiring an image for a plurality of microdroplets, predicting at least one region based on the image for the plurality of microdroplets using an artificial neural network-based prediction model configured to segment at least one region among positive microdroplets, negative microdroplets, and atypical microdroplets, with the image for the plurality of microdroplets as an input, determining a number for the plurality of microdroplets based on the at least one region, and providing quantitative data of targets based on the number for the plurality of microdroplets.Type: ApplicationFiled: December 20, 2021Publication date: May 18, 2023Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Kyoung Gyun LEE, Sung Gap IM, Seok Jae LEE, Youn Seong SONG, Yoo Min PARK, Nam Ho BAE
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Patent number: 11618018Abstract: A modular fluid chip according to an embodiment of the present disclosure includes a body including at least one first hole which allows fluid to flow therethrough; and a housing receiving the body therein, and including a second hole which corresponds to the at least one first hole and allows the fluid to flow therethrough, and a fluid connection part which is connectable to another modular fluid chip.Type: GrantFiled: July 25, 2019Date of Patent: April 4, 2023Assignee: Korea Advanced Institute of Science and TechnologyInventors: Moon Keun Lee, Seok Jae Lee, Nam Ho Bae, Tae Jae Lee, Kyoung Gyun Lee, Yoo Min Park
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Publication number: 20210308672Abstract: A modular fluid chip according to an embodiment of the present disclosure includes a body including at least one first hole which allows fluid to flow therethrough; and a housing receiving the body therein, and including a second hole which corresponds to the at least one first hole and allows the fluid to flow therethrough, and a fluid connection part which is connectable to another modular fluid chip.Type: ApplicationFiled: July 25, 2019Publication date: October 7, 2021Inventors: Moon Keun LEE, Seok Jae LEE, Nam Ho BAE, Tae Jae LEE, Kyoung Gyun LEE, Yoo Min PARK
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Publication number: 20210046472Abstract: A modular fluidic chip according to an embodiment of the present disclosure includes a body configured to have at least one flow channel formed in an inside thereof and be connected to another modular fluidic chip to allow the at least one flow channel to communicate with a flow channel provided in the other modular fluidic chip. According to the embodiment of the present disclosure, a fluidic chip capable of performing one function is formed in the form of a module, whereby a fluidic flow system of various structures can be implemented without restriction in shape or size by connecting a plurality of fluidic chips capable of performing different functions as necessary. Through this, various and accurate experimental data can be obtained, and when a specific portion is deformed or damaged, only the fluidic chip corresponding thereto can be replaced, thereby reducing manufacture and maintenance costs.Type: ApplicationFiled: July 25, 2019Publication date: February 18, 2021Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Seok Jae LEE, Moon Keun LEE, Nam Ho BAE, Tae Jae LEE, Kyoung Gyun LEE, Yoo Min PARK