Abstract: A display device includes a substrate, a first conductive layer on the substrate, the first conductive layer including a data signal line, a first insulating layer on the first conductive layer, a semiconductor layer on the first insulating layer, the semiconductor layer including a first semiconductor pattern, a second insulating layer on the semiconductor layer, and a second conductive layer on the second insulating layer, the second conductive layer including a gate electrode disposed to overlap the first semiconductor pattern, a transistor first electrode disposed to overlap a part of the first semiconductor pattern, wherein the transistor first electrode is electrically connected to the data signal line through a contact hole that penetrates the first and second insulating layers, and a transistor second electrode disposed to overlap another part of the first semiconductor pattern.

Abstract: Provided is a microfluidic device to more easily and effectively operate a valve by improving the structure of valves for controlling a fluid flow more simply and efficiently, which comprises a platform having at least one chamber, at least one flow channel connected to the chambers and transfer fluid, and a valve which opens or closes the flow channel, wherein the valve comprises a body installed in the platform, a blocking plate installed in the body and positioned to face the flow channel to selectively blocks the flow channel, a pressing rod installed to be movable at the inside of the body to press the blocking plate, and a fixing unit installed at the body and fix the pressing rod at a blocking plate pressing position.

Abstract: The present invention may provide a microfluidic device including a rotatable body; a first chamber positioned in a direction of an inner wall of the body; a second chamber positioned in a direction of an outer wall of the body from the first chamber; and a backflow prevention unit, and wherein a fluid is transferred from the first chamber to the second chamber, and wherein the backflow prevention unit prevents a backflow of the fluid from the second chamber to the first chamber.

Abstract: A particle filtering device which shortens the separation time of particles and increases the separation efficiency are provided. The particle filtering device comprises: a filtration membrane which separates a particle by filtering a sample; a first body connected to an inlet side of the filtration membrane, which supplies the sample to the inlet side of the filtration membrane; and a second body connected to an outlet side of the filtration membrane, which accommodates a permeate whose particle is separated through the filtration membrane, wherein the particle filtering device has a structure in which the permeate is accommodated in advance between the second body and the outlet side of the filtration membrane.

Abstract: A device for single-cell analysis according to an embodiment of the present invention comprises: a substrate; a gap between the substrate and porous membrane which is a space for culture medium; and a porous membrane formed on having a pore capable of isolating a second cell into single cell units. A method for single-cell analysis according to an embodiment of the present invention comprises: Culturing a first cell in a culture medium on a bottom side of porous membrane; Applying a sample including a second cell on a porous membrane in a culture medium; Isolating the second cell into single cell units in a pore existing in the porous membrane with a external force such as agitation and gravitational force; Generating an interaction situation between the first cells and the single cell-level second cell; Analyzing a cellular phenomena of the first cell or the second cell.

Abstract: The present disclosure relates to a subfractionation culturing method of a stem cell and proliferation method of a monoclonal stem cell obtained using the same. According to the subfractionation culturing method of stem cells and the proliferation thereof of the exemplary embodiments of the present disclosure, it is advantage that monoclonal stem cells may be quickly obtained without contamination, and desired monoclonal stem cells may be largely obtained in a short time through the rapid proliferation, thereby being used for the preparation of stem cell-therapeutic agents.

Abstract: Provided is a rotatable microfluidic device for conducting simultaneously two or more assays. The device includes a platform which can be rotated, a first unit which is disposed at one portion of the platform and detects a target material from a sample using surface on which a capture probe selectively binds to the target material is attached, and a second unit which is disposed at another portion of the platform and detects a target material included in the sample by a different reaction from the reaction conducted in the first unit.

Abstract: Provided is a microfluidic device to more easily and mechanically operate a valve for controlling a fluid flow, which comprises: a platform having a plurality of chambers; at least one flow channel which connects between the chambers; and a valve which opens or closes the flow channel, wherein the valve includes a blocking member which selectively blocks the flow channel and a pressing member installed in the blocking member to move the blocking member, and the pressing member has a structure which presses and moves the blocking member by the linear reciprocating motion in the same direction as the direction of an external force, and the valve further includes a driving unit which reversibly controls the opening and closing of the flow channel caused by the blocking member by fixing the pressing member to the position of the moved pressing member or returning to the original position.

Abstract: Provided is a nucleic acid purification device which is rotatably installed such that the entire processes of purifying a cell-free nucleic acid from a large amount of blood and a large amount of body fluid are integrated, the nucleic acid purification device including a disk in which a fluid is transferred by a centrifugal force, a supply portion installed in the disk and configured to supply a specimen and a reagent required for nucleic acid purification, an adsorption reaction chamber which is installed in the disk and is connected with the supply portion and in which an adsorption medium for adsorbing a nucleic acid is accommodated and the nucleic acid is adsorbed from the specimen, and a solution accommodating portion which is connected with an output side of an adsorption reaction portion along a centrifugal direction of the disk and in which a solution discharged through the adsorption reaction chamber by the centrifugal force is accommodated and is discharged to the outside.

Abstract: The present invention relates to a centrifugal force-based nanoparticle separation apparatus and method. Specifically, the present invention is based on having a low centrifugal force and a small size, and may thus separate nanovesicles unrelated to antibody specificity in a short time and without using an ultracentrifuge. Further, the present invention requires no additional professional personnel and enables accurate fluid measurement by integrating and automating all processes after sample injection, and may thus reduce the loss of nanovesicles.

Abstract: An organic light emitting diode display device is disclosed which includes: scan, data and power lines crossing one another and arranged to define a pixel region; a switching thin film transistor disposed at an intersection of the scan and data lines; an organic light emitting diode disposed in the pixel region; a driving thin film transistor disposed between the power line and the organic light emitting diode; and a storage capacitor disposed adjacently to the organic light emitting diode and configured to charge a data signal which is applied from the data line. The storage capacitor includes a plurality of sub storage capacitors in which a plurality of storage electrodes are stacked alternately with one another.

Abstract: The present invention provides a rare cell isolation device including: a first body which is disposed above a filtration membrane and includes a first inlet for injecting a biospecimen; and a second body which is disposed under the first body and bonded to the filtration membrane, wherein the first body and the second body have a disk-shaped structure to be rotatable around their centers, and the filtration membrane is disposed to be separated from the center of the second body in a radial direction.

Abstract: A device for single-cell analysis according to an embodiment of the present invention comprises: a substrate; a gap between the substrate and porous membrane which is a space for culture medium; and a porous membrane formed on having a pore capable of isolating a second cell into single cell units. A method for single-cell analysis according to an embodiment of the present invention comprises: Culturing a first cell in a culture medium on a bottom side of porous membrane; Applying a sample including a second cell on a porous membrane in a culture medium; Isolating the second cell into single cell units in a pore existing in the porous membrane with a external force such as agitation and gravitational force; Generating an interaction situation between the first cells and the single cell-level second cell; Analyzing a cellular phenomena of the first cell or the second cell.

Abstract: Provided is a rotatable microfluidic device for conducting simultaneously two or more assays. The device includes a platform which can be rotated, a first unit which is disposed at one portion of the platform and detects a target material from a sample using surface on which a capture probe selectively binds to the target material is attached, and a second unit which is disposed at another portion of the platform and detects a target material included in the sample by a different reaction from the reaction conducted in the first unit.

Abstract: A particle filtering device which shortens the separation time of particles and increases the separation efficiency are provided. The particle filtering device comprises: a filtration membrane which separates a particle by filtering a sample; a first body connected to an inlet side of the filtration membrane, which supplies the sample to the inlet side of the filtration membrane; and a second body connected to an outlet side of the filtration membrane, which accommodates a permeate whose particle is separated through the filtration membrane, wherein the particle filtering device has a structure in which the permeate is accommodated in advance between the second body and the outlet side of the filtration membrane.

Abstract: An organic light emitting diode display device is disclosed which includes: scan, data and power lines crossing one another and arranged to define a pixel region; a switching thin film transistor disposed at an intersection of the scan and data lines; an organic light emitting diode disposed in the pixel region; a driving thin film transistor disposed between the power line and the organic light emitting diode; and a storage capacitor disposed adjacently to the organic light emitting diode and configured to charge a data signal which is applied from the data line. The storage capacitor includes a plurality of sub storage capacitors in which a plurality of storage electrodes are stacked alternately with one another.

Abstract: Provided is a rotatable microfluidic device for conducting simultaneously two or more assays. The device includes a platform which can be rotated, a first unit which is disposed at one portion of the platform and detects a target material from a sample using surface on which a capture probe selectively binds to the target material is attached, and a second unit which is disposed at another portion of the platform and detects a target material included in the sample by a different reaction from the reaction conducted in the first unit.

Abstract: Provided is a microfluidic device to more easily and mechanically operate a valve for controlling a fluid flow, which comprises: a platform having a plurality of chambers; at least one flow channel which connects between the chambers; and a valve which opens or closes the flow channel, wherein the valve includes a blocking member which selectively blocks the flow channel and a pressing member installed in the blocking member to move the blocking member, and the pressing member has a structure which presses and moves the blocking member by the linear reciprocating motion in the same direction as the direction of an external force, and the valve further includes a driving unit which reversibly controls the opening and closing of the flow channel caused by the blocking member by fixing the pressing member to the position of the moved pressing member or returning to the original position.

Abstract: An organic light emitting diode display device is disclosed which includes: scan, data and power lines crossing one another and arranged to define a pixel region; a switching thin film transistor disposed at an intersection of the scan and data lines; an organic light emitting diode disposed in the pixel region; a driving thin film transistor disposed between the power line and the organic light emitting diode; and a storage capacitor disposed adjacently to the organic light emitting diode and configured to charge a data signal which is applied from the data line. The storage capacitor includes a plurality of sub storage capacitors in which a plurality of storage electrodes are stacked alternately with one another.

Abstract: A centrifugal force-based microfluidic device for a multiplexed analysis and an analyzing method using the same are provided. The microfluidic device includes a platform and a microfluidic structure including a plurality of chambers formed within the platform, and valves positioned between the chambers. The microfluidic structure includes a sample separation chamber connected to a sample injection hole, and a plurality of reaction chambers accommodating two or more types of markers specifically reacting with different types of target materials, separately by type. At least one of the target materials is a standard material, and at least one of the markers is a standard marker specifically reacting with the standard material.