Abstract: An embodiment core molding system includes an upper hopper partitioned to define a first accommodating part that accommodates first core sand coated with an organic binder and a second accommodating part that accommodates pure sand, a lower hopper disposed under the upper hopper and connected to the first and second accommodating parts, the lower hopper being configured to measure weights of the first core sand and the pure sand, a mixer connected to the lower hopper, wherein the mixer is configured to allow the first core sand to pass directly therethrough and to accommodate the pure sand, a binder supply unit connected to the mixer and configured to supply an inorganic binder into the mixer, and a core mold configured to mold each of the first core sand and second core sand into a preset shape, the second core sand including the pure sand coated with the inorganic binder.

Abstract: Disclosed are heterocyclic derivatives, and more particularly heterocyclic derivatives having the following Formula I which are useful for the preparation of medicaments for treating diseases related to uric acid: wherein R1, R2, R3, R4, R5, R6, R7, R8, X1, X2, X3, L and Y are the same as defined in the detailed description.

Abstract: The present invention relates to heterocyclic derivatives, and more particularly, to novel heterocyclic derivatives useful for the preparation of medicaments for treating diseases related to uric acid.

Abstract: The present invention relates to novel genipin derivatives which have an excellent liver protection activity with little cytotoxicity, and these compounds are so stable in vivo that they do not induce any side effects.