Patents by Inventor Kyoung S. Kim

Kyoung S. Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IAP antagonists
    Patent number: 9783573
    Abstract: There are disclosed compounds of formula (I) that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
    Type: Grant
    Filed: September 17, 2013
    Date of Patent: October 10, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Robert M. Borzilleri, Kyoung S. Kim, Heidi L. Perez, Erik M. Stang, David K. Williams, Liping Zhang
  • Inhibitors of lysine methyl transferase
    Patent number: 9738630
    Abstract: There are disclosed compounds that are inhibitors of EZH2, pharmaceutical compositions containing said compounds and methods of treating hyperproliferative, inflammatory, infectious, and immunoregulatory disorders and diseases, utilizing the compounds of the invention.
    Type: Grant
    Filed: November 18, 2014
    Date of Patent: August 22, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Kyoung S. Kim, Liping Zhang, Ashok Vinayak Purandare, Steven P. Seitz
  • TGF?R antagonists
    Patent number: 9708316
    Abstract: The invention relates generally to compounds that modulate the activity of TGF?R-1 and TGF?R-2, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
    Type: Grant
    Filed: December 22, 2015
    Date of Patent: July 18, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Brian E. Fink, Yufen Zhao, Robert M. Borzilleri, Liping Zhang, Kyoung S. Kim, Muthoni G. Kamau, Andrew J. Tebben, Yong Zhang, Andrew F. Donnell
  • IAP antagonists
    Patent number: 9637518
    Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: May 2, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Kyoung S. Kim, Liping Zhang, Erik M. Stang
  • IAP antagonists
    Patent number: 9603889
    Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
    Type: Grant
    Filed: October 1, 2013
    Date of Patent: March 28, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Kyoung S. Kim, Liping Zhang, Donna D. Wei
  • IAP ANTAGONISTS
    Publication number: 20160376307
    Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
    Type: Application
    Filed: July 10, 2014
    Publication date: December 29, 2016
    Inventors: Kyoung S. KIM, Liping ZHANG, Erik M. STANG
  • INHIBITORS OF LYSINE METHYL TRANSFERASE
    Publication number: 20160297806
    Abstract: There are disclosed compounds that are inhibitors of EZH2, pharmaceutical compositions containing said compounds and methods of treating hyperproliferative, inflammatory, infectious, and immunoregulatory disorders and diseases, utilizing the compounds of the invention.
    Type: Application
    Filed: November 18, 2014
    Publication date: October 13, 2016
    Inventors: Kyoung S. Kim, Liping Zhang, Ashok Vinandare Purandara, Steven P. Seitz
  • IAP antagonists
    Patent number: 9453048
    Abstract: There are disclosed compounds of formula (I) that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing said compounds.
    Type: Grant
    Filed: August 6, 2013
    Date of Patent: September 27, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Robert M. Borzilleri, Heidi L. Perez, Donna D. Wei, Kyoung S. Kim
  • TGF BETA R ANTAGONISTS
    Publication number: 20160176871
    Abstract: The invention relates generally to compounds that modulate the activity of TGF?R-1 and TGF?R-2, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
    Type: Application
    Filed: December 22, 2015
    Publication date: June 23, 2016
    Inventors: Brian E. Fink, Yufen Zhao, Robert M. Borzilleri, Liping Zhang, Kyoung S. Kim, Muthoni G. Kamau, Andrew J. Tebben
  • IAP antagonists
    Patent number: 9345740
    Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
    Type: Grant
    Filed: July 10, 2013
    Date of Patent: May 24, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventor: Kyoung S. Kim
  • IAP ANTAGONISTS
    Publication number: 20150322111
    Abstract: There are disclosed compounds of formula (I) that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
    Type: Application
    Filed: September 17, 2013
    Publication date: November 12, 2015
    Inventors: Robert M. Borzilleri, Kyoung S. Kim, Heidi L. Perez, Erik M. Stang, David K. Williams, Liping Zhang
  • IAP ANTAGONISTS
    Publication number: 20150238558
    Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
    Type: Application
    Filed: October 1, 2013
    Publication date: August 27, 2015
    Inventors: Kyoung S. Kim, Liping Zhang, Donna D. Wei
  • IAP ANTAGONISTS
    Publication number: 20150225452
    Abstract: There are disclosed compounds of formula (I) that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing said compounds.
    Type: Application
    Filed: August 6, 2013
    Publication date: August 13, 2015
    Inventors: Robert M. Borzilleri, Heidi L. Perez, Donna D. Wei, Kyoung S. Kim
  • IAP ANTAGONISTS
    Publication number: 20150164974
    Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
    Type: Application
    Filed: July 10, 2013
    Publication date: June 18, 2015
    Inventor: Kyoung S. Kim
  • IAP antagonists
    Patent number: 8889712
    Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: November 18, 2014
    Assignee: Bristol-Myers Squibb Company
    Inventors: Robert M. Borzilleri, Heidi L. Perez, Erik M. Stang, Kyoung S. Kim
  • IAP ANTAGONISTS
    Publication number: 20130338081
    Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
    Type: Application
    Filed: June 19, 2013
    Publication date: December 19, 2013
    Inventors: Robert M. Borzilleri, Heidi L. Perez, Erik M. Stang, Kyoung S. Kim
  • Hydroxyphenyl sulfonamides as antiapoptotic bcl inhibitors
    Patent number: 8501992
    Abstract: The present invention provides compound of Formula (I): or a stereoisomer, tautomer, salt or solvate thereof, wherein the variables are defined herein. The compounds of formula (I) are inhibitors of Bcl-2 family antiapoptotic proteins, compositions containing the compounds and methods of treating diseases using the compounds.
    Type: Grant
    Filed: June 8, 2009
    Date of Patent: August 6, 2013
    Assignee: Bristol-Myers Squibb Company
    Inventors: Kyoung S. Kim, Robert M. Borzilleri, Zhen-Wei Cai, Kap-Sun Yeung
  • HYDROXYPHENYL SULFONAMIDES AS ANTIAPOPTOTIC BCL INHIBITORS
    Publication number: 20110294793
    Abstract: The present invention provides compound of Formula (I): or a stereoisomer, tautomer, salt or solvate thereof, wherein the variables are defined herein. The compounds of formula (I) are inhibitors of Bcl-2 family antiapoptotic proteins, compositions containing the compounds and methods of treating diseases using the compounds.
    Type: Application
    Filed: June 8, 2009
    Publication date: December 1, 2011
    Inventors: kyoung S Kim, Robert M. Borzilleri, Zhen-Wei Cai, Kap-Sun Yeung
  • Monocyclic heterocycles as kinase inhibitors
    Patent number: 7989477
    Abstract: The present invention is directed to compounds having the formula and methods for using them for the treatment of cancer.
    Type: Grant
    Filed: March 19, 2010
    Date of Patent: August 2, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: Robert M. Borzilleri, Lyndon A. M. Cornelius, Robert J. Schmidt, Gretchen M. Schroeder, Kyoung S. Kim
  • MONOCYCLIC HETEROCYCLES AS KINASE INHIBITORS
    Publication number: 20100183606
    Abstract: The present invention is directed to compounds having the formula and methods for using them for the treatment of cancer.
    Type: Application
    Filed: March 19, 2010
    Publication date: July 22, 2010
    Inventors: ROBERT M BORZILLERI, Lyndon A.M. Cornelius, Robert J. Schmidt, Gretchen M. Schroeder, Kyoung S. Kim