Patents by Inventor Kypros H. Nicolaides

Kypros H. Nicolaides has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of prenatal screening for trisomy 21
    Patent number: 7922660
    Abstract: Methods for prenatal screening for trisomy 21 employ examination of the fronto-maxillary facial (FMF) angle of a fetus. The methods may comprise obtaining a two or three dimensional image of a fetal face, measuring the FMFbone angle and/or FMFskin angle on the image, and comparing the measured FMFbone angle and/or FMFskin angle with an FMFbone angle and/or FMFskin angle characteristic of chromosomally normal fetuses. A measured FMFbone angle and/or FMFskin angle greater than the FMFbone angle and/or FMFskin angle characteristic of chromosomally normal fetuses provides an indication of an increased likelihood of the occurrence of trisomy 21 in the fetus.
    Type: Grant
    Filed: August 1, 2007
    Date of Patent: April 12, 2011
    Inventors: Jiri D. Sonek, Kypros H. Nicolaides
  • Methods of prenatal screening for trisomy 21
    Publication number: 20080188748
    Abstract: Methods for prenatal screening for trisomy 21 employ examination of the fronto-maxillary facial (FMF) angle of a fetus. In one embodiment, the methods comprise obtaining a two or three dimensional image of a fetal face, measuring the FMFbone angle on the image, and comparing the measured FMFbone angle with an FMFbone angle characteristic of chromosomally normal fetuses, wherein a measured FMFbone angle greater than the FMFbone angle characteristic of chromosomally normal fetuses provides an indication of an increased likelihood of the occurrence of trisomy 21 in the fetus.
    Type: Application
    Filed: August 1, 2007
    Publication date: August 7, 2008
    Inventors: Jiri D. Sonek, Kypros H. Nicolaides