Patents by Inventor Kyril Dambuleff

Kyril Dambuleff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System and method for assembling a large scale chromatography structure
    Patent number: 11045746
    Abstract: A container system is disclosed, where the container system includes a housing. A chromatography cartridge is disposed in the housing. A structural support in the housing is configured to retain the chromatography cartridge within the housing. The housing is configured to withstand a certain amount of pressure generated inside the chromatography cartridge. The chromatography cartridge is disposed in the housing either in horizontal or in vertical position.
    Type: Grant
    Filed: March 8, 2016
    Date of Patent: June 29, 2021
    Assignee: Global Life Sciences Solutions USA LLC
    Inventors: John Davis, Kyril Dambuleff, Alan M. Williams
  • Chromatography column stand
    Patent number: 9687756
    Abstract: A method for conducting maintenance on a chromatography column (1; 51), said column comprising a column tube (32), a top end cell (20) and a bottom end cell (26), where during chromatography said column tube (32) is secured between said top end cell (20) and said bottom end cell (26). Said method comprises the step of rotating at least the top end cell (20) 180 degrees around a horizontal axis before maintenance is conducted to the top end cell (20).
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: June 27, 2017
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Per Lofving, Kyril Dambuleff, John Davis
  • SYSTEM AND METHOD FOR ASSEMBLING A LARGE SCALE CHROMATOGRAPHY STRUCTURE
    Publication number: 20160228791
    Abstract: A container system is disclosed, where the container system includes a housing. A chromatography cartridge is disposed in the housing. A structural support in the housing is configured to retain the chromatography cartridge within the housing. The housing is configured to withstand a certain amount of pressure generated inside the chromatography cartridge. The chromatography cartridge is disposed in the housing either in horizontal or in vertical position.
    Type: Application
    Filed: March 8, 2016
    Publication date: August 11, 2016
    Inventors: John Davis, kYRIL Dambuleff, Alan M. Williams
  • System and method for the automation of column and media packing
    Patent number: 9144754
    Abstract: This invention provides for the fully automated, hands free, packing of chromatography columns by means of delivering a pre-calculated volume of slurry and using two different packing modalities to stop the packing when either 1) this volume has been delivered in the column, or 2) when the adapter is moved to reach a bed height corresponding to the pre-calculated volume. Thus, a chromatography column can be packed in a fully automated fashion and such a column is 1) stable and 2) has the desired performance characteristic.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: September 29, 2015
    Assignee: GE Healthcare Bio-Sciences Corp.
    Inventors: Alan M. Williams, Kyril Dambuleff, Kathryn Taylor, John Davis, Adam Kaletski, Daniel Go, Scott R. Muller
  • CHROMATOGRAPHY COLUMN STAND
    Publication number: 20140131267
    Abstract: A method for conducting maintenance on a chromatography column (1; 51), said column comprising a column tube (32), a top end cell (20) and a bottom end cell (26), where during chromatography said column tube (32) is secured between said top end cell (20) and said bottom end cell (26). Said method comprises the step of rotating at least the top end cell (20) 180 degrees around a horizontal axis before maintenance is conducted to the top end cell (20).
    Type: Application
    Filed: January 21, 2014
    Publication date: May 15, 2014
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: PER USELIUS, KYRIL DAMBULEFF, JOHN DAVIS
  • SYSTEM AND METHOD FOR THE AUTOMATION OF COLUMN AND MEDIA PACKING
    Publication number: 20140076459
    Abstract: This invention provides for the fully automated, hands free, packing of chromatography columns by means of delivering a pre-calculated volume of slurry and using two different packing modalities to stop the packing when either 1) this volume has been delivered in the column, or 2) when the adapter is moved to reach a bed height corresponding to the pre-calculated volume. Thus, a chromatography column can be packed in a fully automated fashion and such a column is 1)stable and 2) has the desired performance characteristic.
    Type: Application
    Filed: November 25, 2013
    Publication date: March 20, 2014
    Applicant: GE Healthcare Bio-Sciences Corp.
    Inventors: ALAN M. WILLIAMS, KYRIL DAMBULEFF, KATHRYN TAYLOR, JOHN DAVIS, ADAM KALETSKI, DANIEL GO, SCOTT R. MULLER
  • Chromatography column stand
    Patent number: 8663477
    Abstract: A method for conducting maintenance on a chromatography column (1; 51), said column comprising a column tube (32), a top end cell (20) and a bottom end cell (26), where during chromatography said column tube (32) is secured between said top end cell (20) and said bottom end cell (26). Said method comprises the step of rotating at least the top end cell (20) 180 degrees around a horizontal axis before maintenance is conducted to the top end cell (20).
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: March 4, 2014
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Per Uselius, Kyril Dambuleff, John Davis
  • CHROMATOGRAPHY COLUMN STAND
    Publication number: 20130341482
    Abstract: A method for conducting maintenance on a chromatography column (1; 51), said column comprising a column tube (32), a top end cell (20) and a bottom end cell (26), where during chromatography said column tube (32) is secured between said top end cell (20) and said bottom end cell (26). Said method comprises the step of rotating at least the top end cell (20) 180 degrees around a horizontal axis before maintenance is conducted to the top end cell (20).
    Type: Application
    Filed: June 21, 2012
    Publication date: December 26, 2013
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: PER USELIUS, KYRIL DAMBULEFF, JOHN DAVIS
  • System and method for the automation of column and media packing
    Patent number: 8607829
    Abstract: This invention provides for the fully automated, hands free, packing of chromatography columns by means of delivering a pre-calculated volume of slurry and using two different packing modalities to stop the packing when either 1) this volume has been delivered in the column, or 2) when the adapter is moved to reach a bed height corresponding to the pre-calculated volume. Thus, a chromatography column can be packed in a fully automated fashion and such a column is 1) stable and 2) has the desired performance characteristic.
    Type: Grant
    Filed: January 11, 2008
    Date of Patent: December 17, 2013
    Assignee: GE Healthcare Bio-Sciences Corp.
    Inventors: Alan M. Williams, Kyril Dambuleff, Kathryn Taylor, John Davis, Adam Kaletski, Daniel Go, Scott R. Muller
  • Chromatography column and maintenance method
    Patent number: 8343349
    Abstract: A method of maintenance of a chromatography column is described which does not require the use of a hoist or crane for disassembly. The method provides improved operator safety by reducing the need for the operator to work below a suspended or supported load within the column. The provision of guide elements which can be reversibly attached to the column facilitates removal or insertion of column components.
    Type: Grant
    Filed: July 17, 2012
    Date of Patent: January 1, 2013
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Stefan Kjell Eriksson, John Davis, Mats O. Hansson, Kyril Dambuleff, Roger Nordberg
  • CHROMATOGRAPHY COLUMN AND MAINTENANCE METHOD
    Publication number: 20120279034
    Abstract: A method of maintenance of a chromatography column is described which does not require the use of a hoist or crane for disassembly. The method provides improved operator safety by reducing the need for the operator to work below a suspended or supported load within the column. The provision of guide elements which can be reversibly attached to the column facilitates removal or insertion of column components.
    Type: Application
    Filed: July 17, 2012
    Publication date: November 8, 2012
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: STEFAN KJELL ERIKSSON, JOHN DAVIS, MATS O. HANSSON, KYRIL DAMBULEFF, ROGER NORDBERG
  • Chromatography column and maintenance method
    Patent number: 8246833
    Abstract: A method of maintenance of a chromatography column is described which does not require the use of a hoist or crane for disassembly. The method provides improved operator safety by reducing the need for the operator to work below a suspended or supported load within the column. The provision of guide elements which can be reversibly attached to the column facilitates removal or insertion of column components.
    Type: Grant
    Filed: December 17, 2009
    Date of Patent: August 21, 2012
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Stefan Kjell Eriksson, John Davis, Mats O. Hansson, Kyril Dambuleff, Roger Nordberg
  • CHROMATOGRAPHY COLUMN AND MAINTENANCE METHOD
    Publication number: 20110147311
    Abstract: A method of maintenance of a chromatography column is described which does not require the use of a hoist or crane for disassembly. The method provides improved operator safety by reducing the need for the operator to work below a suspended or supported load within the column. The provision of guide elements which can be reversibly attached to the column facilitates removal or insertion of column components.
    Type: Application
    Filed: December 17, 2009
    Publication date: June 23, 2011
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Stefan Kjell ERIKSSON, John DAVIS, Mats O. HANSSON, Kyril DAMBULEFF, Roger NORDBERG
  • SYSTEM AND METHOD FOR THE AUTOMATION OF COLUMN AND MEDIA PACKING
    Publication number: 20100313992
    Abstract: This invention provides for the fully automated, hands free, packing of chromatography columns by means of delivering a pre-calculated volume of slurry and using two different packing modalities to stop the packing when either 1) this volume has been delivered in the column, or 2) when the adapter is moved to reach a bed height corresponding to the pre-calculated volume. Thus, a chromatography column can be packed in a fully automated fashion and such a column is 1) stable and 2) has the desired performance characteristic.
    Type: Application
    Filed: January 11, 2008
    Publication date: December 16, 2010
    Inventors: Alan M. Williams, Kyril Dambuleff, Kathryn Taylor, John Davis, Adam Kaletski, Daniel Go, Scott R. Muller
  • SYSTEM AND METHOD FOR ASSEMBLING A LARGE SCALE CHROMATOGRAPHY STRUCTURE
    Publication number: 20100219115
    Abstract: A container system is disclosed, where the container system includes a housing. A chromatography cartridge is disposed in the housing. A structural support in the housing is configured to retain the chromatography cartridge within the housing. The housing is configured to withstand a certain amount of pressure generated inside the chromatography cartridge. The chromatography cartridge is disposed in the housing either in horizontal or in vertical position.
    Type: Application
    Filed: June 18, 2008
    Publication date: September 2, 2010
    Applicant: GE HEALTHCARE BIOSCIENCES CORP.
    Inventors: John Davis, Kyril Dambuleff, Alan M. Williams