Patents by Inventor Kyu-Hyung Han

Kyu-Hyung Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Advanced cell-transducing transport domain-target protein-transport domain fusion protein and uses thereof
    Patent number: 7306944
    Abstract: The present invention provides a fusion protein which delivers a functional protein or peptide into a cell at enhanced efficiency. The fusion protein of the present invention is a transduction domain-target protein-transduction domain fusion protein, wherein the transduction domain, which comprises 6-12 amino acid residues whose more than ¾ consist of arginine or lysine residues, is covalently bonded to each of the amino- and carboxyl-terminal ends of the target protein. Green fluorescence protein and Cu/Zn-superoxide dismutate (SOD) are used as the target protein.
    Type: Grant
    Filed: March 13, 2003
    Date of Patent: December 11, 2007
    Assignee: Polymer Ventures, Inc.
    Inventors: Su-Young Choi, Jin-Seo Park, Kyu-Hyung Han, Jin-Hee Choi
  • Advanced cell-transducing transport domain-target protein-transport domain fusion protein and uses thereof
    Publication number: 20060165634
    Abstract: The present invention provides a fusion protein which delivers a functional protein or peptide into a cell at enhanced efficiency. The fusion protein of the present invention is a transduction domain-target protein-transduction domain fusion protein, wherein the transduction domain, which comprises 6-12 amino acid residues whose more than ¾ consist of arginine or lysine residues, is covalently bonded to each of the amino- and carboxyl-terminal ends of the target protein. Green fluorescence protein and Cu/Zn-superoxide dismutate (SOD) are used as the target protein.
    Type: Application
    Filed: March 13, 2003
    Publication date: July 27, 2006
    Inventors: Su-Young Choi, Jin-Seo Park, Kyu-Hyung Han, Jin-Hee Choi
  • Oligolysine transducing domain, oligolysine-cargo molecule complex and uses thereof
    Publication number: 20040058856
    Abstract: This invention relates to delivery of biologically active organic molecules e.g. peptides or proteins into the cytoplasm. In this invention, transducing domain which is covalently attached to organic molecules is oligolysine which comprise 3-12 lysine residues. The oligolysine transducing domain-binding fusion protein is efficiently transducible into cytoplasm, and biologically active.
    Type: Application
    Filed: September 4, 2003
    Publication date: March 25, 2004
    Inventors: Soo-Young Choi, Jinseu Park, Hyeok-Yil Kwon, Jung-Hoon Kang, Tae-Chun Kang, Moo-Ho Won, Kyu-Hyung Han, Kil-Soo Lee