Abstract: According to an embodiment, a holographic microscope comprises a light source, an optical system splitting light emitted from the light source into an object and a reflective mirror and inducing interference between light reflected by the object or transmitted through the object and light reflected by the reflective mirror, a first image sensor receiving the interference light and sensing interference information for the interference light, a second image sensor receiving the light reflected by the object or transmitted through the object and sensing information for the received light, and an image processor deriving a shape of the object based on the interference information sensed by the first image sensor and the information sensed by the second image sensor.

Abstract: A ceramic electronic component includes a body including a dielectric layer and an internal electrode, and an external electrode disposed on the body and connected to the internal electrode. The dielectric layer includes a plurality of dielectric grains, and at least one of the plurality of dielectric grains has a core-dual shell structure having a core and a dual shell. The dual shell includes a first shell surrounding at least a portion of the core, and a second shell surrounding at least a portion of the first shell, and a concentration of a rare earth element included in the second shell is more than 1.3 times to less than 3.8 times a concentration of a rare earth element included in the first shell.

Abstract: Disclosed are visible light-activatable antitumor self-assembled nanoparticles or antitumor immunity-inducing self-assembled nanoparticles. The self-assembled nanoparticles induce potent apoptosis in cancer cells and increase their own anticancer immunogenicity, thereby maximizing their therapeutic efficacy for cancer.

Abstract: A spectroscopy system that includes a light source portion configured to generate light having a plurality of wavelengths, a light transmitter configured to transmit the light to a target analyte, a light receiving portion configured to receive Raman-scattered light scattered from the target analyte, and a multi-wavelength spectroscopy portion that may acquire a spectrum by splitting the Raman-scattered light transmitted from the light receiving portion. The multi-wavelength spectroscopy portion includes a single diffraction grating configured to diffract the Raman-scattered light and a single concave mirror configured to focus the Raman-scattered light.

Abstract: The present invention provides a system of providing a control service for a TVWS-based hybrid energy storage apparatus in which DC power generated based on solar power is charged into a hybrid solar energy storage device including a plurality of supercapacitors, batteries, supercapacitor modules and battery modules, and the power is supplied to a plurality of loads using the charged power.

Abstract: Disclosed is an optimal peptide-liposome complex capable of multivalent crosslinking with PD-L1 on the cell surface to induce degradation of PD-L1. The peptide-liposome complex effectively blocks PD-L1, an immune checkpoint on the surface of cancer cells, and prevents the recycling of PD-L1 by intracellular metabolism to induce complete degradation of PD-L1 in cancer cells, achieving an increased therapeutic effect on cancer.

Abstract: Disclosed is a prodrug for preventing or treating cancer. The prodrug is mediated by albumin present in the blood to achieve high cancer selectivity for cancer and high stability. Also disclosed is a pharmaceutical composition for preventing or treating cancer including the prodrug. The anticancer prodrug and the pharmaceutical composition form a conjugate with albumin even without using a carrier or delivery vector when injected in vivo. Therefore, the anticancer prodrug and the pharmaceutical composition are effective in preventing or treating cancer, have increased in vivo half-lives, and can accumulate in cancer with increased efficiency to significantly alleviate the side effects of the anticancer drug.

Abstract: Disclosed are visible light-activatable antitumor self-assembled nanoparticles or antitumor immunity-inducing self-assembled nanoparticles. The self-assembled nanoparticles induce potent apoptosis in cancer cells and increase their own anticancer immunogenicity, thereby maximizing their therapeutic efficacy for cancer.

Abstract: The present disclosure relates to a pharmaceutical composition for combination therapy for preventing or treating cancer, which contains a first pharmaceutical ingredient containing a drug conjugate wherein an anticancer agent is bound at one end of an amphiphilic peptide represented by SEQ ID NO 1 and a poloxamer; and a second pharmaceutical ingredient containing an anti-PD-L1 antibody; as active ingredients. The pharmaceutical composition significantly inhibits cancer growth in in-vivo experiments and exhibits an effect of significantly enhancing immunotherapeutic effect by activating immune cells in cancerous tissues. In particular, the pharmaceutical composition for combination therapy according to the present disclosure has superior tumor accumulation efficiency and selectivity as compared to existing anticancer agents, and is very stable with little toxicity to normal tissues other than cancerous tissues.

Abstract: The present invention provides a system of providing a control service for a TVWS-based hybrid energy storage apparatus in which DC power generated based on solar power is charged into a hybrid solar energy storage device including a plurality of supercapacitors, batteries, supercapacitor modules and battery modules, and the power is supplied to a plurality of loads using the charged power.

Abstract: An optical film includes a first pattern layer including a base part and a plurality of protruding parts disposed on the base part, and having a first refractive index, and a second pattern layer disposed on the first pattern layer and having a second refractive index greater than the first refractive index. Each of the protruding parts includes a bottom surface adjacent to the base part, an upper surface opposite to the bottom surface and parallel to the bottom surface, and a side surface disposed between the bottom surface and the upper surface. The side surface includes three or more sub-inclined surfaces, inclination angles of which are different from each other, or includes a curved surface which is convex in a direction of the second pattern layer.

Abstract: An optical film includes a first pattern layer including a base part and protrusion part groups on the base part and having a first refractive index, and a second pattern layer on the first pattern layer and having a second refractive index greater than the first refractive index. Each of the protrusion part groups includes first and second protrusion parts adjacent to each other. Each of the first and second protrusion parts includes a bottom surface, an upper surface, a first side surface and a second side surface. The first and second protrusion parts are symmetrical with respect to a reference line passing through a center of each of the protrusion part groups and perpendicular to the base part. The first and second protrusion parts are asymmetrical with respect to a center line passing through a center of the upper surface and perpendicular to the bottom surface.

Abstract: A method of manufacturing a display panel includes providing a mother substrate in which a plurality of display cell areas is defined from which the display panel will be formed, the display cell areas arranged in along first and directions and each include a display unit cell corresponding to the display panel, and a dummy area extended along the second direction from the display unit cell dividing the mother substrate into the display unit cells each having the dummy area extended therefrom, by performing a wheel cutting process; separating the dummy area from the divided display unit cell by performing a laser cutting process; and curving the display unit cell from which the dummy area is separated, with reference to a reference axis which is parallel to the second direction, to form the display panel.

Abstract: An optical member and a display device including the same. The optical member includes a light guide plate including a surface disposed on a plane defined by a first direction and a second direction crossing the first direction, a low refractive index pattern disposed on the surface of the light guide plate and including an opening for exposing the surface of the light guide plate, a wavelength conversion layer disposed on the low refractive index pattern, and a passivation layer disposed on the wavelength conversion layer and covering a side surface of the wavelength conversion layer and a side surface of the low refractive index pattern at least one side portion. The low refractive index pattern has a lower index of refraction than the light guide plate, and a ratio of an area occupied by the low refractive index pattern to an area of the surface of the light guide plate decreases in the first direction.

Abstract: The present disclosure relates to a pharmaceutical composition for combination therapy for preventing or treating cancer, which contains a first pharmaceutical ingredient containing a drug conjugate wherein an anticancer agent is bound at one end of an amphiphilic peptide represented by SEQ ID NO 1 and a poloxamer; and a second pharmaceutical ingredient containing an anti-PD-L1 antibody; as active ingredients. The pharmaceutical composition significantly inhibits cancer growth in in-vivo experiments and exhibits an effect of significantly enhancing immunotherapeutic effect by activating immune cells in cancerous tissues. In particular, the pharmaceutical composition for combination therapy according to the present disclosure has superior tumor accumulation efficiency and selectivity as compared to existing anticancer agents, and is very stable with little toxicity to normal tissues other than cancerous tissues.

Abstract: An optical film includes a first pattern layer including a base part and protrusion part groups on the base part and having a first refractive index, and a second pattern layer on the first pattern layer and having a second refractive index greater than the first refractive index. Each of the protrusion part groups includes first and second protrusion parts adjacent to each other. Each of the first and second protrusion parts includes a bottom surface, an upper surface, a first side surface and a second side surface. The first and second protrusion parts are symmetrical with respect to a reference line passing through a center of each of the protrusion part groups and perpendicular to the base part. The first and second protrusion parts are asymmetrical with respect to a center line passing through a center of the upper surface and perpendicular to the bottom surface.

Abstract: An optical film includes a first pattern layer including a base part and a plurality of protruding parts disposed on the base part, and having a first refractive index, and a second pattern layer disposed on the first pattern layer and having a second refractive index greater than the first refractive index. Each of the protruding parts includes a bottom surface adjacent to the base part, an upper surface opposite to the bottom surface and parallel to the bottom surface, and a side surface disposed between the bottom surface and the upper surface. The side surface includes three or more sub-inclined surfaces, inclination angles of which are different from each other, or includes a curved surface which is convex in a direction of the second pattern layer.

Abstract: An optical member and display device, the optical member including a diffuser plate, a wavelength conversion layer disposed on a top surface of the diffuser plate, a passivation layer disposed on the wavelength conversion layer and covering a side surface of the wavelength conversion layer on at least one side thereof, and a diffusing pattern layer disposed on and in direct contact with a bottom surface of the diffuser plate and containing diffusion particles.

Abstract: An optical member and a display device including the same. The optical member includes a light guide plate including a surface disposed on a plane defined by a first direction and a second direction crossing the first direction, a low refractive index pattern disposed on the surface of the light guide plate and including an opening for exposing the surface of the light guide plate, a wavelength conversion layer disposed on the low refractive index pattern, and a passivation layer disposed on the wavelength conversion layer and covering a side surface of the wavelength conversion layer and a side surface of the low refractive index pattern at least one side portion. The low refractive index pattern has a lower index of refraction than the light guide plate, and a ratio of an area occupied by the low refractive index pattern to an area of the surface of the light guide plate decreases in the first direction.

Abstract: A hybrid charging/discharging solar energy storage apparatus includes: a solar power generator configured to receive incident solar light and generate electricity; a power converter configured to receive at least power generated by the solar power generator as input power and convert the input power into output power by changing a voltage of the input power; an energy storage unit comprising a plurality of modules configured to store power; a load connection line connected to a load configured to consume power of at least one of the power converter and the energy storage unit; and a power controller configured to control charging and discharging of the energy storage unit according to preset charging/discharging policies.