Patents by Inventor Kyu Pyo Kim

Kyu Pyo Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180180616
    Abstract: The present disclosure relates to a biomarker for predicting the sensitivity to a protein kinase inhibitor and a use thereof. The present disclosure provides a marker, a composition, and a kit for predicting the sensitivity to a protein kinase inhibitor, and a prediction method thereof. According to the present disclosure, the marker has an excellent effect of predicting the sensitivity to a protein kinase inhibitor, and thus the present disclosure can be useful for cancer treatment.
    Type: Application
    Filed: September 3, 2015
    Publication date: June 28, 2018
    Inventors: Tae Won KIM, Dong Hoon JIN, Seung Woo HONG, Jai Hee MOON, Jae Sik SHIN, Ha Reum LEE, Eun Kyoung CHOI, Seung Mi KIM, Soo A JUNG,, Seung Hee HA, Ha Na JUNG, Dae Hee LEE, Seang Hwan JUNG, Jung Shin LEE, Eun Kyung CHOI, Jae Lyun LEE, Yong Sang HONG, Kyu Pyo KIM, Jeong Eun KIM, Seong Joon PARK, Bong Choel KIM
  • Patent number: 9752151
    Abstract: The present invention relates to a composition for treatment or metastasis suppression of cancers which includes a p34 expression inhibitor or activity inhibitor as an active ingredient. According to the present invention, the p34 protein knock-down causes monoubiquitination of PTEN and accordingly nuclear localization of PTEN is induced, as a result, an Akt pathway which is related to survival, proliferation, invasive properties and metastatic properties of tumors is inhibited, and thus there is an effect of significantly reducing clonogenic potential and tumor forming potential of various cancer cells which simultaneously express PTEN and NEDD4-1. Consequently, the p34 gene expression inhibitor or p34 protein activity inhibitor according to the present invention can be effectively used as a treatment agent or a metastasis suppression agent for cancers.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: September 5, 2017
    Assignees: The Asan Foundation, University of Ulsan Foundation for Industry Cooperation
    Inventors: Tae Won Kim, Dong Hoon Jin, Seung Woo Hong, Jai Hee Moon, Jae Sik Shin, Jin Sun Kim, Kyung Ah Jung, Jung Shin Lee, Eun Kyung Choi, Jae Lyun Lee, Yong Sang Hong, Kyu Pyo Kim, Ky Youb Nam, Bong Cheol Kim
  • Publication number: 20160040168
    Abstract: The present invention relates to a composition for treatment or metastasis suppression of cancers which includes a p34 expression inhibitor or activity inhibitor as an active ingredient. According to the present invention, the p34 protein knock-down causes monoubiquitination of PTEN and accordingly nuclear localization of PTEN is induced, as a result, an Akt pathway which is related to survival, proliferation, invasive properties and metastatic properties of tumors is inhibited, and thus there is an effect of significantly reducing clonogenic potential and tumor forming potential of various cancer cells which simultaneously express PTEN and NEDD4-1. Consequently, the p34 gene expression inhibitor or p34 protein activity inhibitor according to the present invention can be effectively used as a treatment agent or a metastasis suppression agent for cancers.
    Type: Application
    Filed: March 27, 2014
    Publication date: February 11, 2016
    Inventors: Tae Won Kim, Dong Hoon Jin, Seung Woo Hong, Jai Hee MOON, Jae Sik Shin, Jin Sun Kim, Kyung Ah Jung, Jung Shin Lee, Eun Kyung Choi, Jae Lyun Lee, Yong Sang Hong, Kyu Pyo Kim, Ky Youb Nam, Bong Cheol Kim