Abstract: A semiconductor memory device includes a substrate including an element separation film and an active region defined by the element separation film, a bit line structure on the substrate, a trench in the element separation film and the active region, the trench on at least one side of the bit line structure and including a first portion in the element separation film and a second portion in the active region, a bottom face of the first portion placed above a bottom face of the second portion, a single crystal storage contact filling the trench, and an information storage element electrically connected to the single crystal storage contact.

Abstract: A semiconductor memory device includes a substrate including an element separation film and an active region defined by the element separation film, a bit line structure on the substrate, a trench in the element separation film and the active region, the trench on at least one side of the bit line structure and including a first portion in the element separation film and a second portion in the active region, a bottom face of the first portion placed above a bottom face of the second portion, a single crystal storage contact filling the trench, and an information storage element electrically connected to the single crystal storage contact.

Abstract: Provided is a T1 contrast agent for magnetic resonance imaging. The T1 contrast agent includes fine iron oxide nanoparticle cores and micelles encapsulating the core particles. The micelles include a nonionic surfactant consisting of a hydrophilic moiety containing at least two chains and a hydrophobic moiety containing at least one C10-C30 hydrocarbon chain. The T1 contrast agent of the present invention is a novel one based on fine iron oxide nanoparticles that can replace conventional gadolinium-based T1 contrast agents. The T1 contrast agent based on fine iron oxide nanoparticles according to the present invention is harmless to humans, is rapidly distributed in the blood, and has a uniform size, ensuring its uniform contrast effect. In addition, the T1 contrast agent of the present invention enables image observation for at least 1 hour to up to 2 hours and is excreted through the kidneys and liver.

Abstract: A semiconductor memory device includes a substrate including an element separation film and an active region defined by the element separation film, a bit line structure on the substrate, a trench in the element separation film and the active region, the trench on at least one side of the bit line structure and including a first portion in the element separation film and a second portion in the active region, a bottom face of the first portion placed above a bottom face of the second portion, a single crystal storage contact filling the trench, and an information storage element electrically connected to the single crystal storage contact.

Abstract: In an externally integrated once-through steam generator type small modular reactor, a steam generator is arranged along the circumference of a reactor vessel, and secondary cooling water flows in heat transfer tubes and changes to superheated steam. The small modular reactor includes: a nuclear reactor including a hemispherical upper head, the reactor vessel cylindrical shell coupled to the upper head and extending downward from the upper head in a cylindrical shape, and a hemispherical lower head provided on a lower portion of the reactor vessel cylindrical shell, wherein a core is placed in the nuclear reactor; the steam generator surrounding all around the reactor vessel cylindrical shell, the steam generator including a first penetration hole communicating with an inside of the nuclear reactor and a second penetration hole separate from the first penetration hole and communicating with the inside of the nuclear reactor.

Abstract: In an externally integrated steam generator type small modular reactor, a steam generator is arranged along the circumference of a reactor vessel cylindrical shell, and a steam drum is arranged along the circumference of the steam generator. The small modular reactor includes: a nuclear reactor including a hemispherical upper head, the reactor vessel cylindrical shell coupled to the upper head and extending downward from the upper head in a cylindrical shape, and a hemispherical lower head provided on a lower portion of the reactor vessel cylindrical shell, wherein a core is placed in the nuclear reactor; the steam generator surrounding all around the reactor vessel cylindrical shell and including a first penetration hole communicating with an inside of the nuclear reactor; and the steam drum surrounding the circumference of the steam generator and including a second penetration hole communicating with an inside of the steam generator.

Abstract: In an externally integrated once-through steam generator type small modular reactor, a steam generator is arranged along the circumference of a reactor vessel, and secondary cooling water flows in heat transfer tubes and changes to superheated steam. The small modular reactor includes: a nuclear reactor including a hemispherical upper head, the reactor vessel cylindrical shell coupled to the upper head and extending downward from the upper head in a cylindrical shape, and a hemispherical lower head provided on a lower portion of the reactor vessel cylindrical shell, wherein a core is placed in the nuclear reactor; the steam generator surrounding all around the reactor vessel cylindrical shell, the steam generator including a first penetration hole communicating with an inside of the nuclear reactor and a second penetration hole separate from the first penetration hole and communicating with the inside of the nuclear reactor.

Abstract: In an externally integrated steam generator type small modular reactor, a steam generator is arranged along the circumference of a reactor vessel cylindrical shell, and a steam drum is arranged along the circumference of the steam generator. The small modular reactor includes: a nuclear reactor including a hemispherical upper head, the reactor vessel cylindrical shell coupled to the upper head and extending downward from the upper head in a cylindrical shape, and a hemispherical lower head provided on a lower portion of the reactor vessel cylindrical shell, wherein a core is placed in the nuclear reactor; the steam generator surrounding all around the reactor vessel cylindrical shell and including a first penetration hole communicating with an inside of the nuclear reactor; and the steam drum surrounding the circumference of the steam generator and including a second penetration hole communicating with an inside of the steam generator.

Abstract: Provided is a pharmaceutical composition for treating corneal endothelium wounds, the composition including angiogenin as an effective ingredient. The present invention relates to a new topical therapeutic use of angiogenin for treatment of corneal endothelium wounds, wherein the angiogenin that is generally known to be involved in angiogenesis activates a PI3K/Akt/eNOS pathway thereof in ocular corneal endothelium to increase migration and proliferation of corneal endothelial cells that are not capable of self-proliferation and to promote prevention and treatment of corneal endothelial cell wounds.

Abstract: Provided is a pharmaceutical composition for treating corneal endothelium wounds, the composition including angiogenin as an effective ingredient. The present invention relates to a new topical therapeutic use of angiogenin for treatment of corneal endothelium wounds, wherein the angiogenin that is generally known to be involved in angiogenesis activates a PI3K/Akt/eNOS pathway thereof in ocular corneal endothelium to increase migration and proliferation of corneal endothelial cells that are not capable of self-proliferation and to promote prevention and treatment of corneal endothelial cell wounds.

Abstract: The present invention relates to a method for manufacturing a combined vaccine capable of concurrently preventing multiple diseases such as diphtheria, tetanus, pertussis, and hepatitis B which should be prevented in an infant. The method for manufacturing a combined vaccine according to the present invention includes the steps of independently adsorbing each protective antigen to an adsorbent of a aluminum hydroxide gel with respect to various diseases such as diphtheria, tetanus, pertussis, and hepatitis B which should be prevented in the infants, and combining each protective antigen adsorbed to the adsorbent after the adsorption. In the present invention, it is possible to concurrently prevent multiple diseases such as diphtheria, tetanus, pertussis, and hepatitis B which should be prevented in the infant using a combined vaccine manufactured according to the present invention.

Abstract: The present invention relates to a method for manufacturing a combined vaccine capable of concurrently preventing multiple diseases such as diphtheria, tetanus, pertussis, and hepatitis B which should be prevented in an infant. The method for manufacturing a combined vaccine according to the present invention includes the steps of independently adsorbing each protective antigen to an adsorbent of a aluminum hydroxide gel with respect to various diseases such as diphtheria, tetanus, pertussis, and hepatitis B which should be prevented in the infants, and combining each protective antigen adsorbed to the adsorbent after the adsorption. In the present invention, it is possible to concurrently prevent multiple diseases such as diphtheria, tetanus, pertussis, and hepatitis B which should be prevented in the infant using a combined vaccine manufactured according to the present invention.

Abstract: An improved device for adjusting a valve lift using external air supply, includes an operating chamber with a piston, and inner and outer valve spring seats with wax whereby in a low speed vehicle, when the engine oil has a high pressure, the heated air expands the wax and compresses a valve spring for adjusting the valve lift so as to effectively improve output power of the vehicle engine.