Abstract: The present invention relates to a composition for preventing or treating macular degeneration, containing a cell permeable nucleic acid complex as an active ingredient and, more specifically, to a pharmaceutical composition for preventing, ameliorating, or treating macular degeneration comprising, a cell-permeable nucleic acid complex containing a bioactive nucleic acid targeting an NLRP3 gene; and a carrier peptide nucleic acid which are complementarily bound to said bioactive nucleic acid, as an active ingredient. The cell permeable nucleic acid complex, in which the bioactive nucleic acid targeting the NLRP3 gene and the carrier peptide nucleic acid are complementarily bound to each other, according to the present invention, has high cell permeability and thus inhibits the expression of NLRP3 without direct injection, and thereby is useful for preventing, ameliorating, or treating macular degeneration.

Abstract: The present invention relates to a method and a kit for detecting alleles of which the specificity and sensitivity in a DNA polymerase chain reaction (PCR), which is widely used for the detection of minor alleles such as single nucleotide polymorphisms or somatic mutations, are increased. More specifically, the present invention relates to a PCR-based method and kit for single nucleotide polymorphism (SNP) genotyping and somatic mutation detection, the method and kit adding a partially or fully double-stranded oligonucleotide for increasing discrimination to a PCR solution for selective amplification of alleles, so that PCR amplification is not affected when a primer 3? terminal base is complementary (3?-matched) to a template but PCR amplification is strongly inhibited when a 3? terminal base is not complementary (3?-mismatched).

Abstract: The present specification provides a composition comprising a material of Chemical Formula 1: having a molecular weight of 500,000 to 700,000 where R1 and R2 are the same as or different from each other, and each independently is hydrogen, deuterium, or an alkyl group, and n is from 10,000 to 20,000, for forming a reverse osmosis membrane protective layer, a method for preparing a reverse osmosis membrane using the same, a reverse osmosis membrane and a water-treatment module.

Abstract: An interlocking fastening upper electrode assembly having an improved fastening force is proposed. The assembly is configured such that a bush inserted into a silicon electrode protrudes above the silicon electrode, and the protruding portion is inserted into and coupled to an anodizing plate so as to suppress rotation of the bush, the assembly including: an inner and outer tab composite nut coupled to an assembly groove of the silicon electrode and an anodizing plate so as to prevent rotation; an inner and outer tab nut assembled in the assembly groove of the silicon electrode and fitted to the outside of the inner and outer tab composite nut; and an assembly module coupled through the inside of a through part of the anodizing plate and assembled with the inner and outer tab composite nut in order to fix the anodizing plate provided above the silicon electrode.

Abstract: The present invention relates to a 6-6 bicyclic ring-containing compound derivative and use thereof. The compound according to the present invention acts as a PRMT5 inhibitor, and thus can be effectively used in the prevention or treatment of diseases caused by PRMT5.

Abstract: Provided herein may be a display device and a method of controlling a plurality of display devices. The method may include displaying, on a first display device, a first image including a first partial image, a second partial image, and a third partial image, transmitting, by the first display device, a second image including a fourth partial image corresponding to the first partial image, a fifth partial image corresponding to the second partial image, and a sixth partial mage corresponding to the third partial image to a second display device, displaying the second image on the second display device, receiving, by the first display device, a first touch input for a first input interface included in the third partial image, and receiving, by the first display device, a second touch input for at least one of the fourth, fifth partial image, and sixth partial images.

Abstract: The display device may include a substrate; at least one pixel along a first direction on the substrate and including first, second, and third emission areas, in each of which a plurality of light emitting elements are provided; a light blocking pattern corresponding to an area between the first to third emission areas; and a color filter layer including a first color filter pattern provided on the first emission area, a second color filter pattern provided on the second emission area, and a third color filter pattern provided on the third emission area. Here, the pixel may include a first storage capacitor, a second storage capacitor, and a third storage capacitor on the substrate and corresponding to one of the first to third color filter patterns.

Abstract: A method for treating a sleep disorder according to an embodiment of the present disclosure includes administering a composition comprising an extract of Hibiscus syriacus as an effective ingredient to a subject in need thereof. Because the Hibiscus syriacus extract of the present invention has an effect of improving sleep time deteriorated by stress, and an effect of reducing the content of corticosterone, which increases due to stress, and increasing the content of serotonin in blood. In addition, the composition has an effect of enhancing in a significant sense the expression of GABAR A ?1 in cerebral cortex, which decreases due to stress, in a group administered with Hibiscus syriacus extract. As such, the composition comprising Hibiscus syriacus extract as an effective ingredient as an effective ingredient can be advantageously used as a functional health food composition or a pharmaceutical composition for preventing, ameliorating or treating sleeping disorders.

Abstract: The present invention relates to an internal chamber processing method, and more particularly, to an internal chamber processing method for performing processing on a chamber and a component inside the chamber. Disclosed is an internal chamber processing method for processing the inside of a chamber in which substrate processing is performed, the method including a pressurizing operation (S100) of raising a pressure inside a chamber to a first pressure (P1) higher than the atmospheric pressure by using a pressurized gas and a depressurizing operation of lowering the pressure inside the chamber from the first pressure (P1) to a second pressure (P2) after the pressurizing operation (S100). The pressurizing operation (S100) and the depressurizing operation (S200) are performed in a state in which a substrate to be processed is removed from the inside of the chamber.

Abstract: The present disclosure relates to a compound derivative containing a 6-7 bicyclic ring and use thereof. The compound according to the present invention can be effectively used in the prevention or treatment of diseases caused by PRMT5 by acting as a PRMT5 inhibitor.

Abstract: A display device includes a display panel including a non-folding area and a sliding area in order along a first direction, a display surface in the non-folding area and the sliding area, and the sliding area including an exposed area of the display surface closest to the non-folding area, the exposed area having a length along the first direction which is variable, a support member coupled to the display panel and movable together with the display panel, and a housing facing the support member with the display panel therebetween and defining an opening corresponding to the non-folding area. The housing is slidably extendable and contractable along the first direction, at the sliding area, the housing which is slidably contracted defines a first length of the exposed area, and the housing which is slidably extended defines a second length of the exposed area which is larger than the first length.

Abstract: A display panel according to an embodiment may include a substrate and light emitting diodes disposed on the substrate. The substrate may include a first display area and a second display area which is disposed adjacent to the first display area and stretchable. The light emitting diodes disposed in the first display area and the second display area on the substrate. The second display area may include first through-parts extending in a first direction, and second through-parts extending in a second direction that is perpendicular to the first direction.

Abstract: The disclosure relates to a display device and a method of driving the same. The display device includes: a display panel which displays an image in a plurality of pixel areas; a timing controller which supplies a control signal for controlling a display position, a display shape, a display size and the number of at least one touch bar; and a data driver which supplies a data signal to display the at least one touch bar at the display position in response to the control signal.

Abstract: Systems and methods are provided for displaying and interacting with multiple open views in a mobile environment. An example method can include displaying a current pane in a maximized state and at least a first pane in a minimized state in a dock area. The current pane is a top of a stack list and displays content associated with a first location and the first pane is in a dock list and displays content associated with a second location. The minimized state for a pane is a scaled down version of the maximized state for the pane, the scale applying to the content for the pane and a size of the pane. The method also includes receiving a drag input on the first pane in the dock area and scaling the size of the first pane according to proximity to the dock area.

Abstract: A method for processing a series of database transactions according to an embodiment includes recording a first transaction requested to a first database by a first application, among the plurality of applications, in association with a transaction group ID, recording a second transaction requested to a second database by a second application called by the first application, among the plurality of applications, in association with the transaction group ID, rolling back the second transaction targeted to the second database in response to a determination that an error has occurred during processing of the second transaction, identifying the first transaction based on the transaction group ID and rolling back the first transaction targeted to the first database.

Abstract: A display device capable of reducing stress applied to a display panel and improving the flexibility of a bendable part of the display panel is provided. According to an embodiment, a display device includes a display panel including a bending region which is partially bent, and a boundary region which is connected to the bending region, a bent location of the bending region varies so that the area of the display panel being exposed in one direction changes, the boundary region includes a plurality of pixels and a plurality of driving circuits for driving the pixels, and the bending region includes a plurality of copy pixels which are driven by the driving circuits of the boundary region.

Abstract: The present invention relates to a cured product having excellent stain resistance and low gloss, a method of manufacturing the same, and an interior material including the cured product. The cured product according to the present invention includes, along with an acrylic oligomer, an oligomer having a functional group containing silicon (Si) and an oligomer having a functional group containing fluorine (F), and thus, has excellent stain resistance and can implement a micro-folded structure on a surface thereof through extreme ultraviolet rays to be used during curing, thereby being capable of realizing low gloss without a matting agent.

Abstract: A display device includes a first display area; a second display area disposed adjacent to the first display area; a driver at least partially disposed in the second display area; a plurality of first light emitting elements disposed in the first display area; a plurality of second light emitting elements disposed in the second display area and including a boundary light emitting element adjacent to the first display area and a driver light emitting element overlapping the driver; and a copy light emitting element and a dummy light emitting element disposed in the second display area and electrically connected to the boundary light emitting element.

Abstract: A method for diagnosing a risk of pancreatic cancer according to an embodiment of the present disclosure includes detecting mutation or functional decrease of one or more gene selected from a group consisting of ARSA (arylsulfatase A), CTSA (cathepsin A), GAA (acid alpha-glucosidase), GALC (galactosylceramidase), HEXB (hexosaminidase subunit beta), IDUA (iduronidase), MAN2B1 (mannosidase alpha class 2B member 1), NPC1 (NPC intracellular cholesterol transporter 1) and PSAP (prosaposin) from a biological sample of a subject, and determining that there is a higher risk of the pancreatic cancer when the mutation or functional decrease of the one or more gene is detected than when neither mutation decrease nor functional decrease is detected.

Abstract: Disclosed are a method for analyzing a melting curve using bi-functional fluorescent PNA probes, a method for diagnosing microsatellite instability (MSI) using the same, and a kit for diagnosing microsatellite instability (MSI) using the same. More particularly, disclosed are a method for analyzing a melting curve, based on the structure of fluorescent PNA probes that bind with different binding forces depending on the number of base mutations deleted using the fluorescent PNA probes capable of specifically binding to regions where the same base is repeated, and a method for rapidly and accurately detecting and analyzing microsatellite instability (MSI) by detecting gene mutation of microsatellite markers caused by base deletion in regions where the same base is repeated using the analysis method and analyzing the number of base mutations thus obtained.