Patents by Inventor KYUNGMIN HAHM

KYUNGMIN HAHM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9775899
    Abstract: Methods of treating neuronal disorders, such as mechanical neuronal traumas and neurodegenerative disorders, with TWEAK or a TWEAK receptor blocking agents are presented.
    Type: Grant
    Filed: December 18, 2012
    Date of Patent: October 3, 2017
    Assignee: Biogen MA Inc.
    Inventors: Linda C. Burkly, Kyungmin Hahm, Timothy Zheng, Steve Perrin, John Lincecum
  • Publication number: 20150291688
    Abstract: The present invention provides methods and agents for the treatment of TWEAK-related conditions, including cardiac, liver, kidney, lung, adipose, skeletal, muscle, neuronal, bone and cartilage conditions. The invention also provides methods for identifying TWEAK agonists or antagonists for the treatment of TWEAK-related conditions. Additionally, the invention provides transgenic animals that express an exogenous DNA encoding a TWEAK polypeptide, or fragments, analogs, or muteins thereof, and methods for using such animals to identify TWEAK agonists or antagonists. The invention further provides methods for diagnosing a disease based on TWEAK expression. The invention also provides methods for affecting cellular differentiation of progenitor cells using TWEAK polypeptides, agonists, or antagonists.
    Type: Application
    Filed: March 18, 2015
    Publication date: October 15, 2015
    Inventors: Linda C. Burkly, Aniela Jakubowski, Timothy Zheng, Kyungmin Hahm
  • Patent number: 9011859
    Abstract: The present invention provides methods and agents for the treatment of TWEAK-related conditions, including cardiac, liver, kidney, lung, adipose, skeletal, muscle, neuronal, bone and cartilage conditions. The invention also provides methods for identifying TWEAK agonists or antagonists for the treatment of TWEAK-related conditions. Additionally, the invention provides transgenic animals that express an exogenous DNA encoding a TWEAK polypeptide, or fragments, analogs, or muteins thereof, and methods for using such animals to identify TWEAK agonists or antagonists. The invention further provides methods for diagnosing a disease based on TWEAK expression. The invention also provides methods for affecting cellular differentiation of progenitor cells using TWEAK polypeptides, agonists, or antagonists.
    Type: Grant
    Filed: April 11, 2013
    Date of Patent: April 21, 2015
    Assignee: Biogen Idec MA Inc.
    Inventors: Linda C. Burkly, Aniela Jakubowski, Timothy Zheng, Kyungmin Hahm
  • Publication number: 20130216496
    Abstract: The present invention provides methods and agents for the treatment of TWEAK-related conditions, including cardiac, liver, kidney, lung, adipose, skeletal, muscle, neuronal, bone and cartilage conditions. The invention also provides methods for identifying TWEAK agonists or antagonists for the treatment of TWEAK-related conditions. Additionally, the invention provides transgenic animals that express an exogenous DNA encoding a TWEAK polypeptide, or fragments, analogs, or muteins thereof, and methods for using such animals to identify TWEAK agonists or antagonists. The invention further provides methods for diagnosing a disease based on TWEAK expression. The invention also provides methods for affecting cellular differentiation of progenitor cells using TWEAK polypeptides, agonists, or antagonists.
    Type: Application
    Filed: April 11, 2013
    Publication date: August 22, 2013
    Applicant: BIOGEN IDEC MA INC.
    Inventors: Linda C. Burkly, Aniela Jakubowski, Timothy Zheng, Kyungmin Hahm
  • Patent number: 8506958
    Abstract: The present invention provides methods and agents for the treatment of TWEAK-related conditions, including cardiac, liver, kidney, lung, adipose, skeletal, muscle, neuronal, bone and cartilage conditions. The invention also provides methods for identifying TWEAK agonists or antagonists for the treatment of TWEAK-related conditions. Additionally, the invention provides transgenic animals that express an exogenous DNA encoding a TWEAK polypeptide, or fragments, analogs, or muteins thereof, and methods for using such animals to identify TWEAK agonists or antagonists. The invention further provides methods for diagnosing a disease based on TWEAK expression. The invention also provides methods for affecting cellular differentiation of progenitor cells using TWEAK polypeptides, agonists, or antagonists.
    Type: Grant
    Filed: April 3, 2009
    Date of Patent: August 13, 2013
    Assignee: Biogen IDEC MA Inc.
    Inventors: Linda C. Burkly, Aniela Jakubowski, Timothy Zheng, Kyungmin Hahm
  • Publication number: 20120183542
    Abstract: Methods of treating neuronal disorders, such as mechanical neuronal traumas and neurodegenerative disorders, with TWEAK or a TWEAK receptor blocking agents are presented.
    Type: Application
    Filed: August 31, 2011
    Publication date: July 19, 2012
    Inventors: Linda C. Burkly, Kyungmin Hahm, Timothy Zheng, Steve Perrin, John Lincecum
  • Publication number: 20120015024
    Abstract: The present invention provides methods and agents for the treatment of TWEAK-related conditions, including cardiac, liver, kidney, lung, adipose, skeletal, muscle, neuronal, bone and cartilage conditions. The invention also provides methods for identifying TWEAK agonists or antagonists for the treatment of TWEAK-related conditions. Additionally, the invention provides transgenic animals that express an exogenous DNA encoding a TWEAK polypeptide, or fragments, analogs, or muteins thereof, and methods for using such animals to identify TWEAK agonists or antagonists. The invention further provides methods for diagnosing a disease based on TWEAK expression. The invention also provides methods for affecting cellular differentiation of progenitor cells using TWEAK polypeptides, agonists, or antagonists.
    Type: Application
    Filed: July 8, 2011
    Publication date: January 19, 2012
    Inventors: Linda C. Burkly, Aniela Jakubowski, Timothy Zheng, Kyungmin Hahm
  • Publication number: 20090311313
    Abstract: The present invention provides methods and agents for the treatment of TWEAK-related conditions, including cardiac, liver, kidney, lung, adipose, skeletal, muscle, neuronal, bone and cartilage conditions. The invention also provides methods for identifying TWEAK agonists or antagonists for the treatment of TWEAK-related conditions. Additionally, the invention provides transgenic animals that express an exogenous DNA encoding a TWEAK polypeptide, or fragments, analogs, or muteins thereof, and methods for using such animals to identify TWEAK agonists or antagonists. The invention further provides methods for diagnosing a disease based on TWEAK expression. The invention also provides methods for affecting cellular differentiation of progenitor cells using TWEAK polypeptides, agonists, or antagonists.
    Type: Application
    Filed: April 3, 2009
    Publication date: December 17, 2009
    Inventors: LINDA C. BURKLY, ANIELA JAKUBOWSKI, TIMOTHY ZHENG, KYUNGMIN HAHM
  • Publication number: 20090124993
    Abstract: Methods of treating neuronal disorders, such as mechanical neuronal traumas and neurodegenerative disorders, with TWEAK or TWEAK-R blocking agents are presented.
    Type: Application
    Filed: February 17, 2006
    Publication date: May 14, 2009
    Inventors: Linda C. Burkly, Kyungmin Hahm, Timothy Zheng, Steve Perrin, John Lincecum
  • Publication number: 20090068102
    Abstract: Methods of treating stroke with blocking agents of TWEAK or TWEAK receptor are presented.
    Type: Application
    Filed: February 15, 2006
    Publication date: March 12, 2009
    Applicants: BIOGEN IDEC MA INC., RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
    Inventors: Linda C. Burkly, Kyungmin Hahm, Marcus Schwaninger, Ionta Inta
  • Publication number: 20060240004
    Abstract: The present invention provides methods and agents for the treatment of TWEAK-related conditions, including cardiac, liver, kidney, lung, adipose, skeletal, muscle, neuronal, bone and cartilage conditions. The invention also provides methods for identifying TWEAK agonists or antagonists for the treatment of TWEAK-related conditions. Additionally, the invention provides transgenic animals that express an exogenous DNA encoding a TWEAK polypeptide, or fragments, analogs, or muteins thereof, and methods for using such animals to identify TWEAK agonists or antagonists. The invention further provides methods for diagnosing a disease based on TWEAK expression. The invention also provides methods for affecting cellular differentiation of progenitor cells using TWEAK polypeptides, agonists, or antagonists.
    Type: Application
    Filed: April 9, 2003
    Publication date: October 26, 2006
    Inventors: Linda Burkly, Aniela Jakubowski, Timothy Zheng, Kyungmin Hahm