Abstract: A cooling structure includes a housing having a cooling channel defined therein through which a coolant flows and includes a sealing cap fitted to a hole of the housing to seal the hole. The sealing cap includes a blocking member configured to be in contact with an internal surface of the housing. The cooling structure may be for cooling a motor, such as an in-wheel vehicle motor.

Abstract: A channel structure includes a cooling channel continuously formed inside a housing. A coolant is configured to flow in the cooling channel. The cooling channel includes a plurality of channel portions spaced apart from each other and extending in the housing by changing directions.

Abstract: According to the present invention, an image encoding apparatus comprises: a motion prediction unit which derives motion information on a current block in the form of the motion information including L0 motion information and L1 motion information; a motion compensation unit which performs a motion compensation for the current block on the basis of at least one of the L0 motion information and L1 motion information so as to generate a prediction block corresponding to the current block; and a restoration block generating unit which generates a restoration block corresponding to the current block based on the prediction block. According to the present invention, image encoding efficiency can be improved.

Abstract: The present invention relates to a positive electrode active material and a lithium secondary battery including the same, and more particularly, to a positive electrode active material including an overlithiated lithium manganese-based oxide, which is able to prevent the degradation of the electrochemical properties of a lithium secondary battery, including rate characteristics, caused by an excess of lithium and manganese in the lithium manganese-based oxide by inducing the growth of primary particles constituting the lithium manganese-based oxide, and prevent the lifetime deterioration of a lithium secondary battery by reducing side reactions between the lithium manganese-based oxide and a liquid electrolyte particularly during high-voltage operation, and at the same time, inhibiting or mitigating the release of a transition metal from the lithium manganese-based oxide, and a lithium secondary battery including the same.

Abstract: The present invention relates to a positive electrode active material and a lithium secondary battery including the same, and more particularly, to a positive electrode active material including an overlithiated lithium manganese-based oxide, and capable of preventing the electrochemical properties of a lithium secondary battery, including rate characteristics, from deteriorating due to lithium and manganese being present in excess in the lithium manganese-based oxide and reducing side reactions between the lithium manganese-based oxide and a liquid electrolyte during high-voltage operation by inducing the growth of a primary particle constituting the lithium manganese-based oxide, and a lithium secondary battery including the same.

Abstract: The present disclosure provides a sealing device and an in-wheel motor including the sealing device. The in-wheel motor includes a stator, a rotor rotatably disposed with respect to the stator, an annular inner seal connected to the stator and spaced apart from the rotor by a predetermined gap so as to be disposed between the stator and the rotor, and an annular slinger coupled to an end portion of the rotor, wherein the annular inner seal seals between the slinger and the in-wheel motor.

Abstract: The present invention relates to a positive electrode active material and a lithium secondary battery including the same, and more particularly, to a bimodal-type positive electrode active material for improving the low energy density per unit volume of an overlithiated lithium manganese-based oxide and a lithium secondary battery including the same.

Abstract: The present invention relates to a positive electrode active material and a lithium secondary battery including the same, and more particularly, to a bimodal-type positive electrode active material which is capable of improving the low energy density per unit volume of an overlithiated lithium manganese-based oxide, preventing the degradation of electrochemical properties of a lithium secondary battery, including rate characteristics, caused by an excess of lithium and manganese in the lithium manganese-based oxide, and particularly preventing the lifetime deterioration of a lithium secondary battery by inhibiting or mitigating the release of a transition metal from the lithium manganese-based oxide, and a lithium secondary battery including the same.

Abstract: The present invention relates to a positive electrode active material and a lithium secondary battery including the same, and more particularly, to a positive electrode active material including an overlithiated lithium manganese-based oxide, and capable of preventing the degradation of electrochemical properties of a lithium secondary battery, including rate characteristics, caused by an excess of lithium and manganese in the lithium manganese-based oxide and reducing side reactions between the lithium manganese-based oxide and a liquid electrolyte during high-voltage operation through induction of the growth of primary particles constituting the lithium manganese-based oxide.

Abstract: The present invention relates to a positive electrode active material and a lithium secondary battery including the same, and more particularly, to a positive electrode active material including an overlithiated lithium manganese-based oxide, and capable of preventing the degradation in electrochemical properties of a lithium secondary battery, including rate characteristics, caused by an excess of lithium and manganese in the lithium manganese-based oxide, and particularly reducing side reactions between the lithium manganese-based oxide and a liquid electrolyte during high-voltage operation, and a lithium secondary battery including the same.

Abstract: The present invention relates to a method of inhibiting, delaying, or reversing cellular senescence that includes having an isolated cell flow through a microchannel, and crashing the cell in flow into an impact surface installed on a flow path of the cell to apply a physical impact to the cell, resulting in inhibiting, delaying, or reversing senescence of the cell, while maintaining high biological activity, and in particular, it relates to a method that can further increase the value of a stem cell as a therapeutic cell for various degenerative diseases by maintaining undifferentiated state of the stem cell even during a long-term culture period to maintain multipotency, and to the cells obtained by the method.

Abstract: The present disclosure provides a method for preparing a polymerization initiator composition, including (a) a step of mixing water and a water-soluble initiator to prepare an aqueous initiator solution having a concentration of 1 to 10%; and (b) a step of activating the aqueous initiator solution, wherein the step of activating is performed by (b-1) a step of heat treating the aqueous initiator solution for 0.5 to 4.5 hours at a temperature of 48 to 62° C.; and (b-2) a step of treating the aqueous initiator solution to achieve pH of 1 to 7, where the steps above are performed in no particular order.

Abstract: According to the present invention, an image encoding apparatus comprises: a motion prediction unit which derives motion information on a current block in the form of the motion information including L0 motion information and L1 motion information; a motion compensation unit which performs a motion compensation for the current block on the basis of at least one of the L0 motion information and L1 motion information so as to generate a prediction block corresponding to the current block; and a restoration block generating unit which generates a restoration block corresponding to the current block based on the prediction block. According to the present invention, image encoding efficiency can be improved.

Abstract: The present disclosure provides a composition for preparing a vinyl chloride-based polymer, including a vinyl chloride-based first seed; a vinyl chloride-based second seed; an initiator composition including a water-soluble initiator and an oil-soluble initiator; a reducing agent; and a vinyl chloride-based monomer, wherein a metal catalyst is not included in the composition, and a method for preparing a vinyl chloride-based polymer using the same.

Abstract: The present disclosure relates to a method for mass production of extracellular vesicles by using a noxa protein-derived peptide and mesenchymal stem cells and, more specifically, to a method for mass production of extracellular vesicles having wound healing and immunomodulatory effects, wherein mesenchymal stem cells are cultured in a medium composition containing a noxa protein-derived peptide, glucose, sucrose, and 3-(N-morpholino)propanesulfonic acid [MOPS], whereby the extracellular vesicles can be obtained at high yield with high purity.

Abstract: The present invention relates to a positive electrode active material and a lithium secondary battery including the same, and more particularly, to a positive electrode active material, which includes an overlithiated lithium manganese-based oxide, which is a solid solution with a phase belonging to a C2/m space group and a phase belonging to an R3-m space group and in which stability degradation caused by excessive amounts of lithium and manganese in the lithium manganese-based oxide is mitigated and/or prevented because there are regions with different proportions of the phase belonging to the C2/m space group and the phase belonging to the R3-m space group in the lithium manganese-based oxide, and a lithium secondary battery including the same.

Abstract: The present invention relates to a positive electrode active material and a lithium secondary battery including the same, and more particularly, to a positive electrode active material which includes an overlithiated lithium manganese-based oxide including at least lithium, nickel, manganese and a doping metal, and in which the degradation in stability caused by excessive amounts of lithium and manganese in the lithium manganese-based oxide is mitigated and/or prevented by controlling the concentration of a transition metal in the lithium manganese-based oxide for each region, and a lithium secondary battery including the same.

Abstract: The present invention relates to a positive electrode active material and a lithium secondary battery including the same, and more particularly, to a positive electrode active material which includes a lithium-rich lithium manganese-based oxide containing at least lithium, nickel, manganese and molybdenum, wherein the lithium manganese-based oxide includes at least one primary particle and a molybdenum-containing flux is used to improve the crystal growth of the primary particle, resulting in mitigation and/or prevention of a decrease in stability caused by lithium and manganese present in excessive amounts in the lithium manganese-based oxide, and a lithium secondary battery including the same.

Abstract: The present disclosure relates to a method for producing extracellular vesicles from three-dimensionally cultured stem cells. The method of the present disclosure can produce stem cell-derived extracellular vesicles with a high yield through orbital shaking culture of stem cell aggregates in the presence of TGF-? and thus can be usefully used in an industrial-scale mass production process of exosomes that can be utilized as a pharmaceutical ingredient substituting for a cell therapeutic agent. Furthermore, the exosomes obtained by the method of the present disclosure have significantly improved immunoregulatory functions as compared to the exosomes produced by the existing method and, therefore, can be applied as a superior therapeutic composition for various inflammations or autoimmune diseases.

Abstract: The present disclosure relates to a composition containing extracellular vesicles isolated from skeletal muscle-derived stem cells as active ingredients, which exhibits the effect of skin aging delay, wound healing, scar reduction and skin whitening, thereby improving skin condition. The present disclosure can not only utilize tissues wasted after surgical operation, thus allowing easy supply of raw materials, but also takes advantage of natural substances, thereby being free from the risk of side effects even upon long-term administration. The composition of the present disclosure promotes the secretion of collagen, reduces reactive oxygen species and promotes re-epithelialization at wound site while remarkably inhibiting melanocyte proliferation, tyrosinase activity and melanogenesis. Accordingly, it can facilitate effective recovery from skin tissue damage caused by oxidative stress, physical wound, intrinsic aging at cell or tissue levels, or hyperpigmentation.