Abstract: The present disclosure provides autotaxin (ATX) inhibitor compounds and compositions including said compounds. The present disclosure also provides methods of using said compounds and compositions for inhibiting ATX. Also provided are methods of preparing said compounds and compositions, and synthetic precursors of said compounds.

Abstract: A substrate processing method is provided. The substrate processing method comprises loading a substrate onto a substrate support inside a chamber, forming a plasma inside the chamber, providing a first DC pulse signal to an electromagnet that generates a magnetic field inside the chamber and processing the substrate with the plasma, wherein the first DC pulse signal is repeated at a first period including a first section and a second section subsequent to the first section, the first DC pulse signal has a first level during the first section, and the first DC pulse signal has a second level different from the first level during the second section.

Abstract: Provided is a method performed by a least one computing device for a message service. The method comprises receiving a transmission request for a compound message which is a bundled message comprising a parent message and a plurality of child messages, obtaining permission information for a sender of the compound message, determining whether to allow each of the child messages to be sent based on the permission information and controlling transmission of the compound message based on the determination result.

Abstract: The present invention provides methods for treating or ameliorating metabolic diseases, cholestatic liver diseases, or organ fibrosis, which comprises administering to a subject a therapeutically effective amount of a pharmaceutical composition comprising an isoxazole derivative, a racemate, an enantiomer, or a diastereoisomer thereof, or a pharmaceutically acceptable salt of the derivative, the racemate, the enantiomer, or the diastereoisomer.

Abstract: A cartridge for a high intensity focused ultrasound (HIFU) device and a piezoelectric linear motor are disclosed. By using the cartridge for a HIFU device according to the present invention, a transducer module is coupled to a piezoelectric linear motor driveable in water and embedded in the cartridge, heat generated when a conventional step motor is driven is fundamentally removed, an additional cooling fan is not needed, ultra-low power consumption and ultra-precise transfer can be realized, and thus an effective procedure can be performed. A skin beauty device may include ultrasound and high frequency units, apply a high frequency to a skin to be treated so as to crack a stratum corneum, and apply ultrasound to the skin to be treated, and thus a medicament drug can easily penetrate the treated skin. In addition, the piezoelectric linear motor in which a piezoelectric actuator and a moving shaft are stably coupled is provided.

Abstract: The present invention relates to a system and a method for determining a stroke based on a voice analysis. According to the present invention, voice data of subjects are collected to extract and analyze voice onset times to determine stroke patients based on voices. The system for determining a stroke generates and collects voice data from test subjects reading a predetermined word that includes a plosive sound. The system for determining a stroke extracts and calculates voice onset times from the voice data to calculate probability parameters for the voice onset times of each of a normal group and a stroke patient group. The system for determining a stroke uses a set of probability parameters to determine an integration section, and calculates probabilities of being in the normal group and the stroke patient group. The system for determining a stroke applies the calculated probabilities to the Bayes theorem to determine whether the subjects are stroke patients.

Abstract: A semiconductor substrate manufacturing method according to an embodiment comprises the steps of: contaminating at least one of a surface layer of a doped semiconductor substrate having a specific resistance of less than 0.1 ?·cm and a bulk layer below the surface layer with at least one metal of Fe, Cu, and Ni; performing dry oxidation at 950° C. for 30 minutes to forcibly form an oxide film on the surface of the semiconductor substrate; and assessing at least one of the presence and the degree of contamination of metal contained in at least one of the oxide film-formed surface layer and bulk layer by using a photoluminescence assessment method.

Abstract: The present invention relates to a system and a method for determining a stroke based on a voice analysis. According to the present invention, voice data of subjects are collected to extract and analyze voice onset times to determine stroke patients based on voices. The system for determining a stroke generates and collects voice data from test subjects reading a predetermined word that includes a plosive sound. The system for determining a stroke extracts and calculates voice onset times from the voice data to calculate probability parameters for the voice onset times of each of a normal group and a stroke patient group. The system for determining a stroke uses a set of probability parameters to determine an integration section, and calculates probabilities of being in the normal group and the stroke patient group. The system for determining a stroke applies the calculated probabilities to the Bayes theorem to determine whether the subjects are stroke patients.

Abstract: A cartridge for a high intensity focused ultrasound (HIFU) device and a piezoelectric linear motor are disclosed. By using the cartridge for a HIFU device according to the present invention, a transducer module is coupled to a piezoelectric linear motor driveable in water and embedded in the cartridge, heat generated when a conventional step motor is driven is fundamentally removed, an additional cooling fan is not needed, ultra-low power consumption and ultra-precise transfer can be realized, and thus an effective procedure can be performed. A skin beauty device may include ultrasound and high frequency units, apply a high frequency to a skin to be treated so as to crack a stratum corneum, and apply ultrasound to the skin to be treated, and thus a medicament drug can easily penetrate the treated skin. In addition, the piezoelectric linear motor in which a piezoelectric actuator and a moving shaft are stably coupled is provided.

Abstract: A semiconductor substrate manufacturing method according to an embodiment comprises the steps of: contaminating at least one of a surface layer of a doped semiconductor substrate having a specific resistance of less than 0.1 ?·cm and a bulk layer below the surface layer with at least one metal of Fe, Cu, and Ni; performing dry oxidation at 950° C. for 30 minutes to forcibly form an oxide film on the surface of the semiconductor substrate; and assessing at least one of the presence and the degree of contamination of metal contained in at least one of the oxide film-formed surface layer and bulk layer by using a photoluminescence assessment method.

Abstract: A display apparatus is provided including: a display; a receiver configured to receive a broadcast signal that includes broadcast content and source information of service content corresponding to the broadcast content; communication circuitry configured to communicate with a server that provides the service content; at least one processor configured: to process the broadcast content received by the communication circuitry to be displayed as an image on the display, to display an image of the service content received using the source information from the server on the display while displaying the image of the broadcast content if it is determined, based on preset setting information, that the service content is allowed to be provided, and to prevent the image of the service content from being displayed while displaying the image of the broadcast content if it is determined, based on the setting information, that the service content is not allowed to be provided.