Abstract: A musical instrument for musical therapy which stimulates and urges patients suffering from dementia, aphasia, and other functional disorders of the brain to voluntarily play and to sing a song comprises an indicating part for displaying the lyrics of a song or other musical indicia in a predetermined pattern, an operating panel, and a scale generator. The indicating part is mounted upon the operating panel, which is provided with a plurality of switch elements arranged in physical alignment with the respective lyrics of the song or other musical indicia. The plural switch elements are connected to the scale generator such that a musical tone or voice signal is output by the scale generator in accordance with a selected switch element. By use of the inventive device, a patient is stimulated and urged to sing the song when the patient successively activates the switch elements corresponding to the displayed lyrics of the song.

Abstract: A process for protection of brain cells comprises orally or parenterally administering into a man suffering from ischemia or being susceptable to ischemia a piperazine derivative having the formula: ##STR1## wherein R.sup.1 is hydrogen or a lower alkyl group, R.sup.2 is hydroxyl, an aralkyloxy group, a lower alkoxy group having 1-5 carbon atoms or a lower alkenyloxy group having 3-5 carbon atoms, R.sup.3 is hydrogen, an aralkyloxy group, a lower alkoxy group having 1-5 carbon atoms or a lower alkenyloxy group having 3-5 carbon atoms and R.sup.4 is hydrogen or a lower alkoxy group having 1-5 carbon atoms.

Abstract: A process for protection of brain cells which comprises orally or parenterally administering into a man suffering from ischemia or being susceptible to ischemia a 1,3-oxazolidin-2-one derivative having the formula: ##STR1## wherein R is a straight or branched chain alkyl having 3-8 carbon atoms, X is hydrogen, halogen, a lower alkyl or alkoxy, and n is 4, 5 or 6. Representative examples of the active component are (4S,5R)-4-(2-methylpropyl)-5-phenyl-3-(3-piperidinopropyl)-1,3-oxazolidin- 2-o ne and (4S,5R)-4-(2-methylpropyl)-3-[3-(perhydroazepin-1-yl)-propyl]-5-phenyl-1,3 -oxazolidin-2-one.