Patents by Inventor L. Clifford Waldrep

L. Clifford Waldrep has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of lung metastases by aerosol delivery of p53 gene and anti-cancer compounds
    Publication number: 20040028616
    Abstract: The present invention provides a method of inhibiting growth of lung metastases in an individual comprising the steps of administering in a combination an aerosolized polyethylenimine-DNA complex and an aerosolized liposome-anticancer drug complex with both of the complexes delivered via aerosolization. Delivery of both the DNA and the anticancer drug via this method inhibits growth of lung metastases in the individual. Also provided is a method of inhibiting growth of lung metastases in an individual by the administration in combination via aerosolization of a polyethylenimine-p53 complex and a dilauroylphosphatidylcholine-9-nitrocamptothecin complex.
    Type: Application
    Filed: February 14, 2003
    Publication date: February 12, 2004
    Inventors: J. Vernon Knight, Brian Gilbert, Nadezhda Koshkina, L. Clifford Waldrep, Charles L. Densmore, Ajay Gautam