Patents by Inventor L. Diane Bruce

L. Diane Bruce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRANEXAMIC ACID ORAL SOLUTION
    Publication number: 20240024235
    Abstract: Methods and compositions are provided for treating a patient having a bleeding disorder during or after a dental procedure to reduce bleeding or need for factor replacement therapy. Aqueous pharmaceutical compositions are provided comprising tranexamic acid, sodium carboxymethyl cellulose, Tween® 20, and menthol wherein the composition exhibits good long term stability, little to no discoloration over time, and reduced bitterness compared to a control solution of tranexamic acid and water.
    Type: Application
    Filed: June 5, 2023
    Publication date: January 25, 2024
    Inventors: Mary Beth G. Erstad, Thomas Gerner Jacobsen, Mohammad Alkhalili, L. Diane Bruce, Paul Hafey
  • Tranexamic acid oral solution
    Patent number: 11666532
    Abstract: Methods and compositions are provided for treating a patient having a bleeding disorder during or after a dental procedure to reduce bleeding or need for factor replacement therapy. Aqueous pharmaceutical compositions are provided comprising tranexamic acid, sodium carboxymethyl cellulose, Tween® 20, and menthol wherein the composition exhibits good long term stability, little to no discoloration over time, and reduced bitterness compared to a control solution of tranexamic acid and water.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: June 6, 2023
    Assignee: Hyloris Developments SA
    Inventors: Mary Beth G. Erstad, Thomas Gerner Jacobsen, Mohammad Alkhalili, L. Diane Bruce, Paul Hafey
  • TRANEXAMIC ACID ORAL SOLUTION
    Publication number: 20190224121
    Abstract: Methods and compositions are provided for treating a patient having a bleeding disorder during or after a dental procedure to reduce bleeding or need for factor replacement therapy. Aqueous pharmaceutical compositions are provided comprising tranexamic acid, sodium carboxymethyl cellulose, Tween® 20, and menthol wherein the composition exhibits good long term stability, little to no discoloration over time, and reduced bitterness compared to a control solution of tranexamic acid and water.
    Type: Application
    Filed: January 9, 2019
    Publication date: July 25, 2019
    Inventors: Mary Beth G. Erstad, Thomas Gerner Jacobsen, Mohammad Alkhalili, L. Diane Bruce, Paul Hafey
  • Method for producing antimicrobial antithrombogenic medical devices
    Patent number: 6528107
    Abstract: A method is provided for producing antimicrobial, antithrombogenic medical devices. The method employs an antimicrobial treatment process wherein an antimicrobial agent is dissolved in an appropriate solvent and the resulting solution is contacted with a portion of a medical device of interest. The antimicrobial treatment process is advantageously performed without the need for additional compounds to facilitate antimicrobial agent uptake into the device. The method further comprises an antithrombogenic treatment process wherein antithrombogenic agents or materials are applied or otherwise associated with at least some portion of the medical device.
    Type: Grant
    Filed: July 22, 1999
    Date of Patent: March 4, 2003
    Assignee: Sulzer Carbomedics Inc.
    Inventors: Joseph A. Chinn, Richard E. Phillips, Jr., Joseph A. Sauter, R. Michael Casanova, Chandrashekhar P. Pathak, Mark A. Moore, L. Diane Bruce