Abstract: Invented is a method of treating degenerative diseases/injuries, in a mammal, including a human, in need thereof which comprises the administration of a therapeutically effective amount of a non-peptide TPO receptor agonist to such mammal.

Abstract: Methods for inhibiting the corrosion of metals in contact with an aqueous system are provided. The method of inhibiting corrosion includes maintaining effective amounts of (1) an amino acid-based polymer, such as a polyaspartic acid compound, and (2) a dispersible and/or soluble tin compound in the aqueous system. The corrosion inhibiting components of the treatment may be added simultaneously or separately into the water of the aqueous system, i.e., provided either in a single treatment product or as separate products. Such a corrosion inhibiting method may optionally also include adding a polycarboxylic acid chelating agent and/or a carboxylate/sulfonate functional copolymer to the aqueous system.

Abstract: A mesh is a collection of multiple shapes referred to as elements, each of which can share an edge with one or more other elements of the mesh. The mesh is presented to the user on a display, and the user identifies a new element to be added to the mesh. User input is received to manipulate the new element (e.g., move the new element around the display). As the new element is manipulated, various conditions are applied to determine edges of elements existing in the mesh that the new element can be snapped to. Snapping a new element to an edge of an existing element in the mesh refers to adding the new element to the mesh so that the new element and the existing element share the edge. Indications of the edges of existing elements to which the new element can be snapped are provided to the user.

Abstract: Dynamic motion path blur techniques are described. In one or more implementations, paths may be specified to constrain a motion blur effect to be applied to a single image. A variety of different techniques may be employed as part of the motion blur effects, including use of curved blur kernel shapes, use of a mesh representation of blur kernel parameter fields to support real time output of the motion blur effect to an image, use of flash effects, blur kernel positioning to support centered or directional blurring, tapered exposure modeling, and null paths.

Abstract: Dynamic motion path blur techniques are described. In one or more implementations, paths may be specified to constrain a motion blur effect to be applied to a single image. A variety of different techniques may be employed as part of the motion blur effects, including use of curved blur kernel shapes, use of a mesh representation of blur kernel parameter fields to support real time output of the motion blur effect to an image, use of flash effects, blur kernel positioning to support centered or directional blurring, tapered exposure modeling, and null paths.

Abstract: Disclosed is a method of enhancing the response of cancer cells in a mammal to treatment with a death receptor ligand, which method comprises contacting the cancer cells with a death receptor ligand in conjunction with an effective amount of a compound described herein, for example, a cucurbitacin (I) or a withanolide (II). Also disclosed is a method of inducing apoptosis in cancer cells in a mammal, comprising contacting the cancer cells with a compound described herein, for example, a cucurbitacin (I) or a withanolide (II) and also contacting the cancer cells with a death receptor ligand, whereby apoptosis is induced in the cancer cells.

Abstract: Electrical connector parts for combining power delivery and signaling in inductively coupled connectors are disclosed. According to one aspect, an electrical connector part includes a first mating connector face having disposed thereon a first set of inductors and also includes a mechanical interface that is configured to maintain the first mating connector face in closely spaced apart relation to a second mating conductor face having disposed thereon a second set of inductors. The mechanical interface is designed to prevent DC coupling and provide inductive AC coupling between at least one pair of inductors made up of one inductor from the first set of inductors and one inductor from the second set of inductors. The first set of inductors includes a power inductor of a first size for transferring power and a data inductor of a second size different from the first size for transferring data.

Abstract: Compositions for inhibiting the corrosion of metals in contact with an aqueous system are provided. The corrosion inhibiting compositions may be used to maintain effective amounts of (1) an amino acid-based polymer, such as a polyaspartic acid compound, and (2) a dispersible and/or soluble tin compound in the aqueous system. The corrosion inhibiting compositions include the amino acid-based polymer and a dispersible and/or soluble tin compound and may optionally include a polycarboxylic acid chelating agent and/or a carboxylate/sulfonate functional copolymer.

Abstract: A method and circuit for implementing field effect transistors (FETs) having a gate within a gate utilizing a replacement metal gate process (RMGP), and a design structure on which the subject circuit resides are provided. A field effect transistor utilizing a RMGP includes a sacrificial gate in a generally central metal gate region on a dielectric layer on a substrate, a source and drain formed in the substrate, a pair of dielectric spacers, a first metal gate and a second metal gate replacing the sacrificial gate inside the central metal gate region, and a second gate dielectric layer separating the first metal gate and the second metal gate. A respective electrical contact is formed on opposite sides of the central metal gate region for respectively electrically connecting the first metal gate and the second metal gate to a respective voltage.

Abstract: Compositions and methods for inhibiting the corrosion of metals in contact with an aqueous system are provided. The method of inhibiting corrosion includes maintaining effective amounts of (1) an amino acid-based polymer, such as a polyaspartic acid compound, and (2) a dispersible and/or soluble tin compound in the aqueous system. The corrosion inhibiting components of the treatment may be added simultaneously or separately into the water of the aqueous system, i.e., provided either in a single treatment product or as separate products. The single treatment single treatment product may include the amino acid-based polymer and a dispersible and/or soluble tin compound. Such a corrosion inhibiting composition may optionally also include a polycarboxylic acid chelating agent and/or a carboxylate/sulfonate functional copolymer.

Abstract: An apparatus (100) for orienting magnetic elements (14) for assembly on a flexible elongated core member (12) includes a plate (104) for supporting the magnetic elements (14). A plurality of magnetic positioning elements (150) are secured to the plate (104) and are configured to position and orient the magnetic elements (14) to facilitate assembly of the elements (14) on the core member (12).

Abstract: Methods, devices and systems are provided for benefit management. One system includes a server including an application interface and access to a data store having one or more client files. A client file can include a definable set of business rules for managing and administering benefits and can include fund use rules for accessing and applying funds to claims from one or more accounts. The system includes a program operable on the server to apply the definable set of business rules in connection with processing a claim.

Abstract: Invented is a method of treating degenerative diseases/injuries, in a mammal, including a human, in need thereof which comprises the administration of a therapeutically effective amount of a non-peptide TPO receptor agonist to such mammal.

Abstract: Invented is a method of treating cancer or a pre-cancerous syndrome in a mammal, including a human, in need thereof which comprises the administration of an effective amount of a non-peptide thrombopoietin (TPO) receptor agonist to such mammal, suitably a human.

Abstract: Invented is a method of treating cardiovascular disease/injury, in a mammal, including a human, in need thereof which comprises the administration of a therapeutically effective amount of a non-peptide TPO receptor agonist to such mammal.

Abstract: The present invention provides an apparatus and method for measuring carbon (any one or all of TC, TOC, or TIC) in a sample matrix. In an embodiment, a method for measuring carbon in a sample composition is provided. The method comprises providing an apparatus comprising a reaction chamber and a diamond coated electrode, wherein the diamond coated electrode is doped with boron. The apparatus further comprises a detector. In addition, the method comprises contacting the sample composition with the electrode. The method further comprises applying an alternating current to the electrode at a sufficient voltage to produce carbon dioxide. Moreover, the method comprises measuring the amount of carbon dioxide produced.

Abstract: Invented is a method of treating cancer or a pre-cancerous syndrome in a mammal, including a human, in need thereof which comprises the administration of an effective amount of a non-peptide thrombopoietin (TPO) receptor agonist to such mammal, suitably a human.

Abstract: The embodiments provide methods of administering a high dose or a loading dose of a TPO modulator to a subject. The embodiments further provide methods of treating thrombocytopenia and/or neutropenia in a subject. Additionally, the embodiments further provide methods of increasing platelet production and/or enhancing the number of peripheral blood stem cells in a subject.

Abstract: Methods, devices and systems are provided for benefit management. One system includes a server including an application interface and access to a data store having one or more client files. A client file can include a definable set of business rules for managing and administering benefits and can include fund use rules for accessing and applying funds to claims from one or more accounts. The system includes a program operable on the server to apply the definable set of business rules in connection with processing a claim.

Abstract: The present invention relates to an inbred sunflower line, designated OID687R. The invention relates to the seeds of inbred sunflower line OID687R, to the plants of inbred sunflower line OID687R and to the methods for producing a sunflower plant, either inbred or hybrid, by crossing the inbred line OID687R with itself or another sunflower line. The invention further relates to methods for producing a sunflower plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other inbred sunflower lines derived from the inbred OID687R.