Patents by Inventor L. Kathryn Durham

L. Kathryn Durham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid molecules, polypeptides and uses therefor, including diagnosis and treatment of Alzheimer's disease
    Publication number: 20040022794
    Abstract: The present invention provides methods and compositions for screening, diagnosis and prognosis of Alzheimer's disease, for monitoring the effectiveness of Alzheimer's disease treatment, and for drug development. Alzheimer's Disease-Associated Features (AFs), detectable by two-dimensional electrophoresis of cerebrospinal fluid, serum or plasma are described. The invention further provides Alzheimer's Disease-Associated Protein Isoforms (APIs) detectable in cerebrospinal fluid, serum or plasma, preparations comprising isolated APIs, antibodies immunospecific for APIs, pharmaceutical compositions, diagnostic and therapeutic methods, and kits comprising or based on the same.
    Type: Application
    Filed: October 3, 2002
    Publication date: February 5, 2004
    Inventors: L. Kathryn Durham, David L. Friedman, Herath Mudiyanselage Athula Chandrasiri Herath, Lida H. Kimmel, Rajesh Bhikhu Parekh, David M. Potter, Christian Rohlff, B. Michael Silber, Peter Jeffrey Snyder, Holly Daria Soares, Thomas R. Stiger, P. Trey Sunderland, Robert Reid Townsend, W. Frost White, Stephen A. Williams
  • Methods, compositions, and kits relating to cardiovascular disease
    Publication number: 20030044810
    Abstract: The present invention relates to technologies for assessing a subject's susceptibility to development of a cardiovascular disorder. The invention further relates to methods for selecting therapeutics which will be optimally effective for treating patients suffering from a cardiovascular disorder. The invention also includes methods, compositions and kits useful for determining a patients cholesteryl ester transfer protein (CETP) genotype.
    Type: Application
    Filed: December 21, 2001
    Publication date: March 6, 2003
    Inventors: L. Kathryn Durham, Maruja E. Lira, Patrice M. Milos
  • Nucleic acid molecules, polypeptides and uses therefor, including diagnosis and treatment of alzheimer's disease
    Publication number: 20020164668
    Abstract: The present invention provides methods and compositions for screening, diagnosis and prognosis of Alzheimer's disease, for monitoring the effectiveness of Alzheimer's disease treatment, and for drug development. Alzheimer's Disease-Associated Features (AFs), detectable by two-dimensional electrophoresis of cerebrospinal fluid, serum or plasma are described. The invention further provides Alzheimer's Disease-Associated Protein Isoforms (APIs) detectable in cerebrospinal fluid, serum or plasma, preparations comprising isolated APIs, antibodies, pharmaceutical compositions, diagnostic and therapeutic methods, and kits comprising or based on the same.
    Type: Application
    Filed: April 3, 2001
    Publication date: November 7, 2002
    Inventors: L. Kathryn Durham, David L. Friedman, Herath Mudiyanselage Athula Chandrasiri Herath, Lida H. Kimmel, Rajesh Bhikhu Parekh, David M. Potter, Christian Rohlff, B. Michael Silber, Thomas R. Stiger, P. Trey Sunderland, Robert Reid Townsend, W. Frost White, Stephen A. Williams