Patents by Inventor L. S. Klaudyne Hong

L. S. Klaudyne Hong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230187067
    Abstract: A system for disease prediction includes processing circuitry configured to receive a dataset including data of a pa -tient population, the data including for each of a plurality of patients of the patient population, values for a plurality of features, and a diagnosis value indicating whether a disease has been diagnosed. The processing circuitry is configured to, based on correlations between the values, select from the dataset a plurality of subsets of the features, and, for each of at least one of the subsets, execute a machine learning process with the respective subset and the diagnosis values as input parameters, the execution generating a respective prediction model. The processing circuitry is configured to output the respective prediction model.
    Type: Application
    Filed: March 23, 2017
    Publication date: June 15, 2023
    Inventors: L.S. Klaudyne Hong, Gerald Wogan, Luigi Vacca, Bruce Tidor
  • Publication number: 20210282649
    Abstract: Systems and methods are disclosed for predicting values for health parameters traditionally sampled at higher frequencies (such as vital signs) and at lower frequencies (such as lab results). The higher frequency parameter predictions can take the form of a time series of predicted vital sign values and the lower frequency parameter predictions can be single predicted values based on statistical measures of past collected input features. Suitable statistical measures can include the maximum, minimum and median values.
    Type: Application
    Filed: October 29, 2020
    Publication date: September 16, 2021
    Inventors: L.S. Klaudyne Hong, Luigi Vacca
  • Publication number: 20190259499
    Abstract: Various aspects of the subject technology related to systems and methods for predicting sequential organ failure assessment (SOFA) scores using machine learning. A system may be configured to receive patient data including one or more features associated with one or more patients. The system may process the features using one or more SOFA score prediction models derived from at least one machine learning process to output respective predicted SOFA scores. One of the prediction models has been trained to output a first SOFA component score for a first amount of time into the future and a second prediction model has been trained to output a second SOFA component score for the first amount of time into the future. The system may output on a graphical user interface, a total SOFA score, the first SOFA component score, and the second SOFA components score predicted for the respective patient.
    Type: Application
    Filed: October 18, 2017
    Publication date: August 22, 2019
    Inventors: L.S. Klaudyne Hong, Gerald Wogan, Luigi Vacca, Bruce Tidor
  • Patent number: 9102915
    Abstract: Compositions and methods for the growth and expansion of mammalian cells in culture are provided. In particular, methods for the growth and expansion of postpartum-derived cells in vitro are provided using surfaces such as microcarrier beads.
    Type: Grant
    Filed: November 13, 2007
    Date of Patent: August 11, 2015
    Assignee: Depuy Synthes Products, Inc.
    Inventors: Alexander M. Harmon, L. S. Klaudyne Hong, Anthony J. Kihm, Anna Gosiewska
  • Publication number: 20140170748
    Abstract: This invention provides for methods of growing anchorage-dependent cells (e.g. hUTC) in culture medium comprising amino acids, vitamins, salts nucleosides, insulin, transferrin, ethanolamine and sodium selenium, wherein the culture medium is supplemented with serum. The method further comprises addition of a serum-free nutrient solution comprising amino acids, vitamins, salts nucleosides, insulin, transferrin, ethanolamine and sodium selenium. The invention also provides for culture media and serum-free nutrient solutions for growing anchorage-dependent cells.
    Type: Application
    Filed: December 14, 2012
    Publication date: June 19, 2014
    Applicant: DePuy Synthes Products, LLC
    Inventors: Ravinder Bhatia, L.S. Klaudyne Hong, Sadettin S. Ozturk, Venkat Haricharan Kamaraju
  • Patent number: 8361459
    Abstract: Cells derived from postpartum tissue such as the umbilical cord and placenta, and methods for their use to regenerate, repair, and improve neural tissue, and to improve behavior and neurological function in stroke patients are disclosed.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: January 29, 2013
    Assignee: Advanced Technologies and Regenerative Medicine, LLC
    Inventors: Darin J. Messina, Sanjay K. Mistry, L. S. Klaudyne Hong, Brian C. Kramer, Michael J. Romanko, Anna Gosiewska
  • Patent number: 7875272
    Abstract: Cells derived from postpartum tissue such as the umbilical cord and placenta, and methods for their use to regenerate, repair, and improve neural tissue, and to improve behavior and neurological function in stroke patients are disclosed.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: January 25, 2011
    Assignee: Ethicon, Incorporated
    Inventors: Darin J. Messina, Sanjay Mistry, L. S. Klaudyne Hong, Brian C. Kramer, Michael J. Romanko, Anna Gosiewska
  • Patent number: 7875273
    Abstract: Cells derived from postpartum tissue such as the umbilical cord and placenta, pharmaceutical compositions comprising such cells, and methods for using such cells and pharmaceutical compositions to treat patients having a neurodegenerative condition of the substantia nigra or striatum, such as Parkinson's disease, are provided.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: January 25, 2011
    Assignee: Ethicon, Incorporated
    Inventors: Darin J. Messina, Sanjay Mistry, L. S. Klaudyne Hong, Brian C. Kramer, Michael J. Romanko
  • Publication number: 20100215714
    Abstract: Cells derived from postpartum tissue such as the umbilical cord and placenta, and methods for their use to regenerate, repair, and improve neural tissue, and to improve behavior and neurological function in stroke patients are disclosed.
    Type: Application
    Filed: January 29, 2010
    Publication date: August 26, 2010
    Applicant: Ethicon, Incorporated
    Inventors: Darin J. MESSINA, Sanjay K. Mistry, L.S. Klaudyne Hong, Brian C. Kramer, Michael J. Romanko, Anna Gosiewska
  • Patent number: 7618622
    Abstract: Cells derived from postpartum tissue such as the umbilical cord and placenta, pharmaceutical compositions comprising such cells, and methods for using such cells and pharmaceutical compositions to treat patients having a neurodegenerative condition of the substantia nigra or striatum, such as Parkinson's disease, are provided.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: November 17, 2009
    Assignee: Ethicon, Incorporated
    Inventors: Darin J. Messina, Sanjay Mistry, L. S. Klaudyne Hong, Brian C. Kramer, Michael J. Romanko
  • Publication number: 20080166328
    Abstract: Compositions and methods for the growth and expansion of mammalian cells in culture are provided. In particular, methods for the growth and expansion of postpartum-derived cells in vitro are provided using surfaces such as microcarrier beads.
    Type: Application
    Filed: November 13, 2007
    Publication date: July 10, 2008
    Applicant: Ethicon, Inc.
    Inventors: Alexander M. Harmon, L.S. Klaudyne Hong, Anthony J. Kihm, Anna Gosiewska