Patents by Inventor László FÓNAGY

László FÓNAGY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of carboprost and its tromethamine salt
    Patent number: 10442762
    Abstract: The subject of the invention is a novel process for the preparation of Carboprost tromethamine salt where alkylation the enone of the general formula (II) is carried out in the presence of a chiral auxiliary in aprotic solvent with a Grignard reagent. The methyl ester epimers of formula (VII) are separated by gravity silica gel chromatography and the salt formation is carried out by using solid tromethamine base.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: October 15, 2019
    Assignee: CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA ZRT.
    Inventors: Péter Buzder-Lantos, Zsuzsanna Kardos, Irén Hortobágyi, István Lászlófi, Imre Juhász, László Fónagy, Csaba Váradi, Ágnes Nagyné Borkó
  • PROCESS FOR THE PREPARATION OF CARBOPROST AND ITS TROMETHAMINE SALT
    Publication number: 20180362457
    Abstract: The subject of the invention is a novel process for the preparation of Carboprost tromethamine salt where alkylation the enone of the general formula (II) is carried out in the presence of a chiral auxiliary in aprotic solvent with a Grignard reagent. The methyl ester epimers of formula (VII) are separated by gravity silicagel chromatography and the salt formation is carried out by using solid tromethamine base.
    Type: Application
    Filed: November 10, 2016
    Publication date: December 20, 2018
    Applicant: CHINOIN GYÓGYSZER ÉS VEGYÉSZETI TERMÉKEK GYÁRA ZRT .
    Inventors: Péter BUZDER-LANTOS, Zsuzsanna KARDOS, Irén HORTOBÁGYI, István LÁSZLÓFI, Imre JUHÁSZ, László FÓNAGY, Csaba VÁRADI, Ágnes NAGYNÉ BORKÓ