Abstract: A horizontal wellbore logging, mapping and characterization system uses new variables of in situ stress fields, natural vertical fracture systems, with sensors and transducers, to acquire data for directional drilling and well completion design. System may be operated from end of coiled tubing base station, or conduct autonomous measurements and experiments. It constitutes a downhole smart system utilizing AI, and robotic means for mechanical property, reservoir, and structural characterizations. Video cameras front, side, and rear looking with LED lights allow observation of experiments in real time, and entire lateral wellbore mapping of natural vertical fracture systems to design and implement new drilling and open-hole well completion methodologies without use of mud, water, cement, or steel pipe cemented in the laterals. The characterizations and models developed following the logging process can be used interactively in the drilling and completion of oil and gas wells.

Abstract: An open-hole drilling method and process is embodied in creation of a closed cycle and system for extracting gas from shale and other impermeable and natural vertical fracture dominated reservoirs. The closed cycle system enables gas from reservoir to be used as a drilling fluid, with any excess gas produced as the wellbore is extended, to be sold in real time through a gas pipeline. Since only natural gas exists throughout the closed system, no risk exists for downhole explosions, and no wellbore damages occur from foreign fluids, such as mud, cement, and water. Limits of wellbore length due to gas produced while drilling, and risks during gas flaring are eliminated. All products produced from wellbore are captured so no venting of any liquids, gases, or solids. All hydraulic fracturing issues are avoided. Gas flow rate measurements while drilling enables technical, financial, reserve estimate models development in real time.

Abstract: A method for diagnosing or treating disease associated with a gut or intestinal tract includes collecting samples of gut microbiota from along an intestinal tract of a patient; perturbing the intestinal tract of the patient; and obtaining a response of the perturbing the intestinal tract of the patient. The method can be implemented using one or more capsules designed for introducing stimuli into the gut or intestinal tract, observing the response to the stimulus, and treating the gut or intestinal tract in view of the response to the stimulus and further in view of acquired empirical data compiled into a database.

Abstract: A comprehensive system for gut in vivo exploration, discovery, characterization, research, diagnostics, and treatment comprising three different ingestible capsules and their associated methodologies, is provided for medical research and patient care. The system of tools is focused on discovery of causes of gut-based illnesses, treating, and curing them. The capsules perform unique functions, and as an in vivo healthcare system, provide for sampling, testing or diagnosing gut processes as a function of the length of the gut “x” and at any point in time “t”, including simultaneous chemical substance sampling and testing, along with the associated microbes. The in vivo system allows medications or system perturbation substances delivery, in a prescribed manner to the point of interest, and the resulting substances and microbes are simultaneously sampled upstream and downstream at the exact point and time of delivery.

Abstract: An orally ingestible capsule device with monitoring and control instruments is provided for practicing physicians to use in patient examining rooms. The Capsule is part of an in vivo gastrointestinal tract (GI Tract or Gut) healthcare system with capabilities of delivering medications to any point in the gut, administering them at any time, or autonomously based upon onboard measurements, and simultaneously measuring results, along with extra body function measurements. It is capable of delivering gut medications or autoimmune perturbation substances and simultaneously measure responses and sample gut substances/microbes at application points. Objectives, as part of patient diagnosis, include determining microbe roles in the patient's digestion process, along with toxic substances in contributing to illnesses or diseases, such as gluten sensitivities.

Abstract: An interactive research device comprised of an orally ingested capsule with pockets rendering the capsule capable of sampling intestinal tracts (gut) substances and microbes before, during and after delivery of system perturbation substances and methods of use and associate system are described. Sensors are provided to simultaneously measure, monitor, record, and transmit data in real time obtained from within the exact vicinity of substance deployment and location of microbial assisted digestive processes. In vivo collected samples are also collected and preserved for in vitro analysis. Digestive processes and dysfunctions involving proteins that result in “gluten sensitivities” and dozens of gut-based diseases that develop in stages, and have been mysteries for over 2,000 years, can be analyzed. The capabilities were developed to permit research within the heretofore inaccessible and important regions of the small intestine where villi functions are compromised, and in the upper colon.

Abstract: An orally ingested capsule has capabilities of sampling gut substances and microbes before, during and after delivery of system perturbation substances, to the gut at any point or time. Sensors are provided to simultaneously measure, monitor, record, and transmit data in real time obtained within the exact vicinity of substance deployment and microbial assisted digestive processes occur. In vivo collected samples are collected and preserved for extensive in vitro analysis. Digestive processes and dysfunctions involving proteins that result in “gluten sensitivities” and dozens of gut-based diseases that develop in stages, and have been mysteries for over 2,000 years, can be analyzed. The capabilities were developed to permit research within the heretofore inaccessible and important regions of the small intestine where villi functions are compromised, and in the upper colon.

Abstract: An orally ingestible capsule device with monitoring and control instruments is provided for practicing physicians to use in patient examining rooms. The Capsule is part of an in vivo gut healthcare system with capabilities of delivering medications to any point in the gut, administering them at any time, or autonomously based upon onboard measurements, and simultaneously measuring results, along with extra body function measurements. It is capable of delivering gut medications or autoimmune perturbation substances and simultaneously measuring responses and sample gut substances/microbes at application points. Objectives, as part of patient diagnosis, include determining microbe roles in the patient's digestion process, along with toxic substances contributing to illnesses or diseases, such as gluten sensitivities.

Abstract: Many diseases with origin in human gut are of unknown causes, so only symptoms are treated. Endoscopic devices leave about 15? of gut unexplored other than by autopsy. Thus, a substance and microbe simultaneous sample collecting, testing, evaluation, and characterization system has been invented that will provide data for evaluating functions, macro, and micro processes taking place along entire length of the human digestive and intestinal tract from mouth to anus. The entire digestive process including biochemical reactions and microbe roles, and consequences, as pertain to diseases and illnesses can be ascertained through applications of the system, which includes protocols, for collection and preservation of digestion products for external analysis, measurements of many in vivo conditions, and internally processing data and making decisions based upon said processed data, including administration of medications.

Abstract: A method serving as a catalyst and tool for improving the fundamental processes vital to a community by applying a quantitative, interlaced, simultaneous, multi-disciplinary, systems engineering approach to improve and maximize achievement of goals and processes occurring within a city or greater extended community, such as, a large watershed area. The method involves a specifically designed facility, a computer-based mathematical model, and an exemplary methodology for public participation based on the mathematical relationship and interdependencies of the educational activity, economic development, ecological preservation, environmental issues, research activity, and entertainment and recreation activity of the community.