Patents by Inventor Lacramioara Bintu

Lacramioara Bintu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fractional regulation of transcription
    Patent number: 11674144
    Abstract: A method of controlling the number of cells in a population of cells having silenced transcription of a target nucleic acid as a function of time includes recruiting a chromatin regulator (CR) to a site proximal to a transcription initiation site of the target nucleic acid to form a fraction of silenced cells in the population of cells. The chromatin regulator may be EED, KRAB, DNMT3, HDAC4, EZH2, REST, or a combination thereof.
    Type: Grant
    Filed: April 18, 2016
    Date of Patent: June 13, 2023
    Assignee: California Institute of Technology
    Inventors: Michael Elowitz, Lacramioara Bintu, John Yong
  • FRACTIONAL REGULATION OF TRANSCRIPTION
    Publication number: 20160304872
    Abstract: A method of controlling the number of cells in a population of cells having silenced transcription of a target nucleic acid as a function of time includes recruiting a chromatin regulator (CR) to a site proximal to a transcription initiation site of the target nucleic acid to form a fraction of silenced cells in the population of cells. The chromatin regulator may be EED, KRAB, DNMT3, HDAC4, EZH2, REST, or a combination thereof.
    Type: Application
    Filed: April 18, 2016
    Publication date: October 20, 2016
    Inventors: Michael Elowitz, Lacramioara Bintu, John Yong