Patents by Inventor Ladislav Vyklicky

Ladislav Vyklicky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STEROIDAL COMPOUNDS FOR TREATMENT OF MENTAL AND NEUROLOGICAL DISORDERS
    Publication number: 20200330484
    Abstract: The present invention provides steroidal compounds for the treatment of mental and neurological disorders by targeted rectification of defects caused by a mutation occurring in the membrane region of a human N-methyl-D-aspartate receptor subunit by potentiation of the effects of the said receptor.
    Type: Application
    Filed: November 26, 2018
    Publication date: October 22, 2020
    Applicants: USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I., FYZIOLOGICKY USTAV AV CR, V. V. I.
    Inventors: Eva KUDOVA, Ladislav VYKLICKY
  • Amphiphilic compounds with neuroprotective properties
    Patent number: 10017535
    Abstract: Amphiphilic compounds with tetradecahydrophenanthrene skeleton and their enantiomers, exhibiting neuroprotective effects, their use in methods of treatment of neuropsychiatric disorders associated with an imbalance in glutamatergic neurotransmitter system, such as ischemic damage of CNS, neurodegenerative changes and disorders of CNS, affective disorders, depression, post-traumatic stress disorder and diseases related to stress, anxiety, schizophrenia and psychotic disorders, pain, addiction, multiple sclerosis, epilepsy, glioma, and a pharmaceutical composition containing compound.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: July 10, 2018
    Assignees: USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I., FYZIOLOGICKY USTAV AV CR, V.V.I.
    Inventors: Eva Kudova, Hana Chodounska, Vojtech Kapras, Ladislav Vyklicky, Karel Vales, Ullrich Jahn
  • AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES
    Publication number: 20170240588
    Abstract: Amphiphilic compounds with tetradecahydrophenanthrene skeleton and their enantiomers, exhibiting neuroprotective effects, their use in methods of treatment of neuropsychiatric disorders associated with an imbalance in glutamatergic neurotransmitter system, such as ischemic damage of CNS, neurodegenerative changes and disorders of CNS, affective disorders, depression, post-traumatic stress disorder and diseases related to stress, anxiety, schizophrenia and psychotic disorders, pain, addiction, multiple sclerosis, epilepsy, glioma, and a pharmaceutical composition containing compound.
    Type: Application
    Filed: August 25, 2015
    Publication date: August 24, 2017
    Applicants: USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, v.v.i., FYZIOLOGICKY USTAV AV CR, v.v.i.
    Inventors: Eva KUDOVA, Hana CHODOUNSKA, Vojtech KAPRAS, Ladislav VYKLICKY, Karel VALES, Ullrich JAHN
  • PREGNANOLONE DERIVATIVES SUBSTITUTED IN 3ALPHA-POSITION WITH THE CATIONIC GROUP, METHOD OF THEIR PRODUCTION, USAGE AND PHARMACEUTICAL PREPARATION INVOLVING THEM
    Publication number: 20130338383
    Abstract: Pregnanolone derivatives, substituted in 3 alpha-position with the cationic group, of general formula I, and a method of the production of these compounds and their utilization for treatment of neuropsychiatric disorders related to imbalance of glutamatergic neurotransmitter system, such as ischemic damage of CNS, neurodegenerative changes and disorders of CNS, affective disorders, depression, post traumatic stress disorder, and other diseases related to stress, anxiety, schizophrenia, and psychotic disorders, pain, addictions, multiple sclerosis, epilepsy, and gliomas. The compounds are also used for production of veterinary and human pharmaceutical preparation for treatment of above mentioned diseases and for production of pharmaceutical preparations containing these compounds.
    Type: Application
    Filed: February 15, 2012
    Publication date: December 19, 2013
    Applicants: FYZIOLOGICKY USTAV AKADEMIE VED CESKE REPUBLICKY, V.V.I., USTAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY, V.V.I.
    Inventors: Hana Chodounska, Vojtech Kapras, Ladislav Vyklicky, Jirina Borovska, Vojtech Vyklicky, Karel Vales, Ales Stuchlik, Lukas Rambousek
  • Steroide anionic compounds, method of their production, usage and pharmaceutical preparation involving them
    Patent number: 8575376
    Abstract: A compound with general formula I for treatment of various diseases of the central nervous system, in treatment of neuropsychiatric disorders related to imbalance of glutamatergic neurotransmitter system, ischemic damage of CNS, neurodegenerative changes and disorders of CNS, affective disorders, depression, PTSD and other diseases related to stress, anxiety, schizophrenia and psychotic disorders, pain, addictions, multiple sclerosis, epilepsy and gliomas.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: November 5, 2013
    Assignees: Ustav Organicke Chemie A Biochemie Akademie Ved Ceske Republiky, V.V.I., Fyziologicky Ustav Akadamie Ved Ceske Republiky, V.V.I., Psychiatricke Centrum Praha
    Inventors: Hana Chodounska, Eva Stastna, Vojtech Kapras, Ladislav Kohout, Jirina Borovska, Ladislav Vyklicky, Karel Vales, Ondrej Cais, Lukas Rambousek, Ales Stuchlik, Vera Valesova
  • STEROIDE ANIONIC COMPOUNDS, METHOD OF THEIR PRODUCTION, USAGE AND PHARMACEUTICAL PREPARATION INVOLVING THEM
    Publication number: 20120071453
    Abstract: A compound with general formula I for treatment of various diseases of the central nervous system, in treatment of neuropsychiatric disorders related to imbalance of glutamatergic neurotransmitter system, ischemic damage of CNS, neurodegenerative changes and disorders of CNS, affective disorders, depression, PTSD and other diseases related to stress, anxiety, schizophrenia and psychotic disorders, pain, addictions, multiple sclerosis, epilepsy and gliomas.
    Type: Application
    Filed: May 28, 2010
    Publication date: March 22, 2012
    Inventors: Hana Chodounska, Eva Stastna, Vojtech Kapras, Ladislav Kohout, Jirina Borovska, Ladislav Vyklicky, Karel Vales, Ondrej Cais, Lukas Rambousek, Ales Stuchlik, Vera Valesova