Patents by Inventor Laetitia Shintu

Laetitia Shintu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of toxicological evaluation, method of toxicological screening and associated system
    Patent number: 9448226
    Abstract: The present invention relates to a method of toxicological evaluation of a candidate substance on at least one tissue or organ, characterized in that it comprises the steps of: (a) obtaining a bioartificial tissue or organ by simulation or modelling of the metabolic activity of said tissue or organ by at least one bioreactor; (b) exposure of said bioartificial tissue or organ to said substance; (c) observation of the metabolic response of the bioartificial tissue or organ and acquisition without a priori of an associated multidimensional data set; (d) identification by means of a method of multivariate statistical analysis of the components of the multidimensional data set which are quantitatively correlated with predetermined variables; (e) generation of a predictive model on the basis of the components of the data set that are actually retained; (f) testing of the predictive nature of said model by at least one statistical method of estimating reliability; (g) identification of the metabolic response of the
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: September 20, 2016
    Assignees: Universite Technologie De Compiegne—UTC, Centre National de la Recherche Scientifique (CNRS), Ecole Normale Superieure De Lyon, Institut National De L'Environment Industriel Et Des Risques
    Inventors: Marc-Emmanuel Dumas, Eric Leclerc, Laetitia Shintu, Regis Baudoin, Cécile Legallais, Pierre Toulhoat, Céline Brochot
  • METHOD OF TOXICOLOGICAL EVALUATION, METHOD OF TOXICOLOGICAL SCREENING AND ASSOCIATED SYSTEM
    Publication number: 20130060550
    Abstract: The present invention relates to a method of toxicological evaluation of a candidate substance on at least one tissue or organ, characterized in that it comprises the steps of: (a) obtaining a bioartificial tissue or organ by simulation or modelling of the metabolic activity of said tissue or organ by at least one bioreactor; (b) exposure of said bioartificial tissue or organ to said substance; (c) observation of the metabolic response of the bioartificial tissue or organ and acquisition without a priori of an associated multidimensional data set; (d) identification by means of a method of multivariate statistical analysis of the components of the multidimensional data set which are quantitatively correlated with predetermined variables; (e) generation of a predictive model on the basis of the components of the data set that are actually retained; (f) testing of the predictive nature of said model by at least one statistical method of estimating reliability; (g) identification of the metabolic response of the
    Type: Application
    Filed: May 12, 2011
    Publication date: March 7, 2013
    Applicants: UNIVERSITE TECHNOLOGIE DE COMPIEGNE - UTC, INSTITUT NATIONAL DE L'ENVIRONNEMENT INDUSTRIEL ET DES RISQUES, ECOLE NORMALE SUPERIEURE DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Marc-Emmanuel Dumas, Eric Leclerc, Laetitia Shintu, Regis Baudoin, Cécile Legallais, Pierre Toulhoat, Céline Brochot