Patents by Inventor Lai-Han Elaine Leung

Lai-Han Elaine Leung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190175526
    Abstract: One embodiment relates to a method of treating cancer by administering a compound of Formula I to a patient.
    Type: Application
    Filed: December 13, 2017
    Publication date: June 13, 2019
    Inventors: Xiao Jun YAO, Lai Han Elaine LEUNG, Liang LIU, Jia Hui XU, Qian Qian WANG, Ying LI
  • Publication number: 20190175553
    Abstract: One embodiment is a method of treating cancer. The method includes administering a therapeutically effective amount of a compound to a patient.
    Type: Application
    Filed: January 24, 2019
    Publication date: June 13, 2019
    Inventors: Xiao Jun YAO, Lai Han Elaine LEUNG, Liang LIU, Qian Qian WANG, Jia Hui XU, Ying LI
  • Patent number: 10278955
    Abstract: One embodiment is a method of treating cancer. The method includes administering a therapeutically effective amount of a compound to a patient.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: May 7, 2019
    Assignee: Macau University of Science and Technology
    Inventors: Xiao Jun Yao, Lai Han Elaine Leung, Liang Liu, Qian Qian Wang, Jia Hui Xu, Ying Li
  • Patent number: 10208028
    Abstract: One embodiment is a method of treating cancer. The method includes administering a therapeutically effective amount of a compound to a patient.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: February 19, 2019
    Assignee: Macau University of Science and Technology
    Inventors: Lai Han Elaine Leung, Xiao Jun Yao, Liang Liu, Jia Hui Xu, Ying Li, Qian Qian Wang
  • Publication number: 20180348222
    Abstract: A method of treating a subject, in particular a human, suffering from non-small cell lung cancer includes administering a bufadienolide to the subject. A method of inhibiting the proliferation and inducing the cell death of non-small cell lung cancer cells, a method of inhibiting the Epidermal growth factor receptor (EGFR) kinase activity in non-small cell lung cancer cells harboring an abnormality in the EGFR gene, and a method of inhibiting Na+/K+-ATPase in non-small cell lung cancer cells includes contacting those cells with a bufadienolide. Proscillaridin A as bufadienolide, with the structure of Formula (III) has advantageously high cytotoxicity against EGFR-dependent non-small cell lung cancer at nano-molar levels while having low toxicity to normal lung cells.
    Type: Application
    Filed: June 1, 2017
    Publication date: December 6, 2018
    Inventors: Liang Liu, Lai-Han Elaine Leung, Xiao-Jun Yao, Run-Ze Li, Xing-Xing Fan
  • Patent number: 9884046
    Abstract: One embodiment relates to a method of treating lung cancer by administering a compound of formula I to a patient.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: February 6, 2018
    Assignee: Macau University of Science and Technology
    Inventors: Xiao Jun Yao, Lai Han Elaine Leung, Liang Liu, Xing Xing Fan, Chun Xie
  • Patent number: 9884047
    Abstract: One example embodiment relates to a method of treating non-small cell lung cancer by administering a compound of formula (I) to a patient.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: February 6, 2018
    Assignee: Macau University of Science and Technology
    Inventors: Xiao Jun Yao, Lai Han Elaine Leung, Liang Liu, Xing Xing Fan, Chun Xie
  • Patent number: 9744145
    Abstract: This invention provides a method of treating lung cancer including administering a therapeutically effective amount of a compound of 0089-0022 formula I to a subject in need thereof. The compound activates pyruvate kinase M2 isoform (PKM2) to treat the lung cancer. In one example, the lung cancer is Non-Small Cell Lung Cancer (NSCLC).
    Type: Grant
    Filed: January 16, 2017
    Date of Patent: August 29, 2017
    Assignee: Macau University of Science and Technology
    Inventors: Liang Liu, Lai-Han Elaine Leung, Xiao-Jun Yao, Run-Ze Li