Abstract: A fan blade includes a hub and a blade connected to a circumferential side face of the hub. The blade presents a circular shape, the inner annular surface of the blade encloses a hollow area. In the radial direction of the hub, an end of the blade connected to the hub is the root part of the blade. In a direction from the end part to the root part, at least a portion of the area of the blade is a first segment part that includes a first inner annular surface and a first outer annular surface. In the axial direction of the hub, the first inner annular surface and the first outer annular surface turn direction at the end part, and the first inner annular surface and the first outer annular surface on both sides of the end part do not overlap.

Abstract: A method includes: a first apparatus and a second apparatus determine a type of a target obfuscation function corresponding to a first sensing scenario and a parameter included in the target obfuscation function; the first apparatus generates a first signal and a second signal, where the second signal is obtained by applying the target obfuscation function to perform phase adjustment on the first signal and the target obfuscation function is determined based on the type of the target obfuscation function and the parameter; the first apparatus outputs the first signal and the second signal, sends first signal through a first antenna corresponding to the first apparatus, and sends the second signal through a second antenna corresponding to the first apparatus; and correspondingly, the second apparatus receives signals from the first apparatus and obtains a sensing result based on the received signals and the target obfuscation function.

Abstract: A gas delivery system configured to provide deposition and etch gases to a processing chamber for a rapid alternating process includes a first valve arranged to provide deposition gas from a deposition gas manifold to a first zone of a gas distribution device via a first orifice and provide the deposition gas from the deposition gas manifold to a second zone of the gas distribution device via a second orifice having a diameters than the first orifice. A second valve is arranged to provide etch gas from the etch gas manifold to the first zone of the gas distribution device via a third orifice and provide the etch gas from the etch gas manifold to the second zone of the gas distribution device via a fourth orifice having a different diameter than the third orifice.

Abstract: A system and method are disclosed for automating cryogenic electron microscopy (cryo-EM) data collection by optimizing a sampling strategy. The system identifies, from patch-level images taken by a cryo-EM instrument, a plurality of holes within a cryo-EM grid, each representing a candidate data collection point. The system predicts an expected reward for each identified hole based on features extracted from the patch-level images. The system determines, using stochastic approximation, a dynamically adjusted threshold quality score representing an estimated optimal time-average reward. Holes are selected from the identified plurality based on the expected reward by minimizing an objective function that depends on the dynamically adjusted threshold quality score. The dynamically adjusted threshold quality score may be based at least in part on observed rewards from the selected holes and microscope operation times.

Abstract: Provided herein are screening methods and animal models related to intraocular diseases such as age-related macular degeneration (AMD), for example, for identifying candidate therapeutics for treating or preventing eye diseases, such as AMD. Also provided herein are compounds/compositions that are useful for killing or inhibiting the growth of a microorganism, such as Bacillus megaterium. Further provided herein are methods of using the compounds/compositions for treating infections with a microorganism, such as Bacillus megaterium and for treating or preventing diseases or disorders associated with such infections, such as AMD.

Abstract: Provided herein are screening methods and animal models related to intraocular diseases such as age-related macular degeneration (AMD), for example, for identifying candidate therapeutics for treating or preventing eye diseases, such as AMD. Also provided herein are compounds/compositions that are useful for killing or inhibiting the growth of a microorganism, such as Bacillus megaterium. Further provided herein are methods of using the compounds/compositions for treating infections with a microorganism, such as Bacillus megaterium and for treating or preventing diseases or disorders associated with such infections, such as AMD.

Abstract: The present invention relates to a salt of (6-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)pyrimidin-2-yl)-1-methyl-1H-indol-2-yl)(3,3-difluoroazetidine-1-yl)methanone (herein referred to as “compound A”), a solid form of the salt, a method for preparing the solid form, a pharmaceutical composition comprising the solid form, and uses of the solid form as a Rho-associated protein kinase (ROCK) inhibitor, preferably a selective ROCK2 inhibitor.

Abstract: A system includes: a hydrogen internal combustion engine configured to produce exhaust; an aftertreatment system in exhaust receiving communication with the hydrogen internal combustion engine, the aftertreatment system comprising a catalyst member; a sensor coupled to the aftertreatment system; and a controller configured to: receive, from the sensor, data corresponding to a characteristic of the aftertreatment system, determine, based on the characteristic, a performance value corresponding to the catalyst member, compare the performance value to a threshold, cause the hydrogen internal combustion engine to operate in a first engine operating mode when the performance value does not exceed the threshold, and cause the hydrogen internal combustion engine to operate in a second engine operating mode when the performance value exceeds the threshold.

Abstract: In some examples, a flat Bottom Shadow Ring (fBSR) is provided for processing a substrate in a processing chamber. An example fBSR comprises an overhang for covering an edge of the substrate in the processing chamber. The overhang includes a flat zone that extends radially outward over the outer edge of the substrate.

Abstract: An aero-engine limit protection control method and apparatus, a storage medium and a device belong to the technical field of aero-engine control. Through the design of a main controller and a limit controller, the present invention realizes the effects of tracking of high-pressure rotational speed and the limit of turbine outlet temperature respectively. A Lyapunov function is designed. The stability of a closed-loop system is analyzed under the average dwell-time restriction. Controller parameter conditions that satisfy stability analysis are obtained by solving inequalities. The proposed method not only realizes the purpose of limit protection control of the aero-engine in a transition stage and improves the safety of an aero-engine control system, but also theoretically analyzes the stability of the aero-engine limit protection control system and improves the reliability of engineering application.

Abstract: A split type precisely-anchorable transcatheter valve-in-ring system comprises a split transcatheter valve-in-ring anchoring stent (10) and a transcatheter artificial biological valve-in-ring (20), wherein the shape and structure of the transcatheter valve-in-ring anchoring stent (10) are matched with the real structure of the annuloplasty ring and supravalvular and infravalvular tissues after three-dimensional reconstruction based on imaging data of a patient who have undergone valve failure after implantation of a annuloplasty ring (30), the transcatheter valve-in-ring anchoring stent (10) is firstly delivered to the patient's failed annuloplasty ring for release, deformation and alignment with the supravalvular and infravalvular tissues of the failed annuloplasty ring; the transcatheter artificial biological valve-in-ring (20) is delivered to the transcatheter valve-in-ring anchoring stent (10) for release, the stent of the transcatheter artificial biological valve-in-ring (20) deforms and expands to the f

Abstract: In some examples, a flat Bottom Shadow Ring (fBSR) is provided for processing a substrate in a processing chamber. An example fBSR comprises an overhang for covering an edge of the substrate in the processing chamber. The overhang includes a fiat zone that extends radially outward over the outer edge of the substrate.

Abstract: Systems and methods described herein relate to the prediction of effects of data purging on data sources that are related through hierarchical data relationships. A purge request comprises a set of purge parameters that identify a data source and define one or more purge criteria for purging of data items of the data source. A plurality of impacted data sources is identified based on one or more hierarchical data relationships held by the data items of the data source. The impacted data sources include the data source and one or more additional data sources. The purge parameters are provided to a machine learning model to obtain output indicative of a predicted effect of execution of the purge request on the impacted data sources. The predicted effect is caused to be presented at the user device prior to the execution of the purge request.

Abstract: A fan blade includes a hub and a blade connected to a circumferential side face of the hub. The blade presents a circular shape, the inner annular surface of the blade encloses a hollow area. In the radial direction of the hub, an end of the blade connected to the hub is the root part of the blade. In a direction from the end part to the root part, at least a portion of the area of the blade is a first segment part that includes a first inner annular surface and a first outer annular surface. In the axial direction of the hub, the first inner annular surface and the first outer annular surface turn direction at the end part, and the first inner annular surface and the first outer annular surface on both sides of the end part do not overlap.

Abstract: An apparatus to generate a first vertex output representing a vertex stream comprising a first list of vertices for opaque objects of a first frame of the scene, generate a first set of hash values using data associated with the first list of vertices for opaque objects of the first frame of the scene, generate a second vertex output representing a vertex stream comprising a second list of vertices for opaque objects of a second frame of the scene, generate a second set of hash values using data associated with the second list of vertices for opaque objects of the second frame of the scene, match opaque objects of the first frame of the scene with opaque objects of the second frame of the scene using the first set of hash values and the second set of hash values, and execute a render operation using the transformed vertex outputs.

Abstract: A sealing device, comprising includes a sealing ring including a sealing lip composed of an insulating elastic material for forming dynamic sealing with respect to a conductive component; a support body fixed on the sealing ring along the circumferential direction of the sealing ring, and a first detection unit comprising two first support bodies in the support body, first cables respectively electrically connected to the corresponding first support bodies, and a loop detection device electrically connected to the first cables, wherein the first support bodies are arranged at the sealing ring such that radial ends of the first support bodies close to the conductive component are covered with the insulating elastic material at the sealing lip and can directly contact the conductive component after the sealing lip is worn. The two first support bodies, the conductive component, the loop detection device, and the first cables jointly form a communication loop.

Abstract: A system includes: a hydrogen internal combustion engine configured to produce exhaust; an aftertreatment system in exhaust receiving communication with the hydrogen internal combustion engine, the aftertreatment system comprising a catalyst member; a sensor coupled to the aftertreatment system; and a controller configured to: receive, from the sensor, data corresponding to a characteristic of the aftertreatment system, determine, based on the characteristic, a performance value corresponding to the catalyst member, compare the performance value to a threshold, cause the hydrogen internal combustion engine to operate in a first engine operating mode when the performance value does not exceed the threshold, and cause the hydrogen internal combustion engine to operate in a second engine operating mode when the performance value exceeds the threshold.

Abstract: The present disclosure provides viral vectors which decrease undesired or off-target gene expression. Particularly, the present disclosure provides recombinant viral vectors comprising a transcription termination sequence adjacent to an inverted terminal repeat sequence (e.g., downstream of a first inverted terminal repeat sequence and upstream of an expression cassette), and virus or virus-like particles, compositions, and methods of using thereof.

Abstract: Provided are compositions, devices and systems, methods for assessing, treating and/or preventing an intraocular disease or disorder in a subject, wherein the etiology of the intraocular disease or disorder comprises infection of a microorganism in the intraocular space or cavity of the subject. Provided are compositions, devices and systems, and methods for assessing, treating and/or preventing age-related macular degeneration (AMD) in a subject, e.g., a human patient.

Abstract: Systems and methods described herein relate to the real-time verification of data purges. A first subprocess of a data purging process is executed to purge a plurality of data items. A system accesses purge result data providing an indication of a result of the first subprocess. The system determines, based on the purge result data, that the first subprocess was not executed in accordance with a purge policy associated with the data purging process. In response to determining that the first subprocess was not executed in accordance with the purge policy, the system adjusts a state of the data purging process. A second subprocess of the data purging process is then executed according to the adjusted state.