Abstract: A split type precisely-anchorable transcatheter valve-in-ring system comprises a split transcatheter valve-in-ring anchoring stent (10) and a transcatheter artificial biological valve-in-ring (20), wherein the shape and structure of the transcatheter valve-in-ring anchoring stent (10) are matched with the real structure of the annuloplasty ring and supravalvular and infravalvular tissues after three-dimensional reconstruction based on imaging data of a patient who have undergone valve failure after implantation of a annuloplasty ring (30), the transcatheter valve-in-ring anchoring stent (10) is firstly delivered to the patient's failed annuloplasty ring for release, deformation and alignment with the supravalvular and infravalvular tissues of the failed annuloplasty ring; the transcatheter artificial biological valve-in-ring (20) is delivered to the transcatheter valve-in-ring anchoring stent (10) for release, the stent of the transcatheter artificial biological valve-in-ring (20) deforms and expands to the f

Abstract: In some examples, a flat Bottom Shadow Ring (fBSR) is provided for processing a substrate in a processing chamber. An example fBSR comprises an overhang for covering an edge of the substrate in the processing chamber. The overhang includes a fiat zone that extends radially outward over the outer edge of the substrate.

Abstract: Systems and methods described herein relate to the prediction of effects of data purging on data sources that are related through hierarchical data relationships. A purge request comprises a set of purge parameters that identify a data source and define one or more purge criteria for purging of data items of the data source. A plurality of impacted data sources is identified based on one or more hierarchical data relationships held by the data items of the data source. The impacted data sources include the data source and one or more additional data sources. The purge parameters are provided to a machine learning model to obtain output indicative of a predicted effect of execution of the purge request on the impacted data sources. The predicted effect is caused to be presented at the user device prior to the execution of the purge request.

Abstract: A fan blade includes a hub and a blade connected to a circumferential side face of the hub. The blade presents a circular shape, the inner annular surface of the blade encloses a hollow area. In the radial direction of the hub, an end of the blade connected to the hub is the root part of the blade. In a direction from the end part to the root part, at least a portion of the area of the blade is a first segment part that includes a first inner annular surface and a first outer annular surface. In the axial direction of the hub, the first inner annular surface and the first outer annular surface turn direction at the end part, and the first inner annular surface and the first outer annular surface on both sides of the end part do not overlap.

Abstract: An apparatus to generate a first vertex output representing a vertex stream comprising a first list of vertices for opaque objects of a first frame of the scene, generate a first set of hash values using data associated with the first list of vertices for opaque objects of the first frame of the scene, generate a second vertex output representing a vertex stream comprising a second list of vertices for opaque objects of a second frame of the scene, generate a second set of hash values using data associated with the second list of vertices for opaque objects of the second frame of the scene, match opaque objects of the first frame of the scene with opaque objects of the second frame of the scene using the first set of hash values and the second set of hash values, and execute a render operation using the transformed vertex outputs.

Abstract: A sealing device, comprising includes a sealing ring including a sealing lip composed of an insulating elastic material for forming dynamic sealing with respect to a conductive component; a support body fixed on the sealing ring along the circumferential direction of the sealing ring, and a first detection unit comprising two first support bodies in the support body, first cables respectively electrically connected to the corresponding first support bodies, and a loop detection device electrically connected to the first cables, wherein the first support bodies are arranged at the sealing ring such that radial ends of the first support bodies close to the conductive component are covered with the insulating elastic material at the sealing lip and can directly contact the conductive component after the sealing lip is worn. The two first support bodies, the conductive component, the loop detection device, and the first cables jointly form a communication loop.

Abstract: A system includes: a hydrogen internal combustion engine configured to produce exhaust; an aftertreatment system in exhaust receiving communication with the hydrogen internal combustion engine, the aftertreatment system comprising a catalyst member; a sensor coupled to the aftertreatment system; and a controller configured to: receive, from the sensor, data corresponding to a characteristic of the aftertreatment system, determine, based on the characteristic, a performance value corresponding to the catalyst member, compare the performance value to a threshold, cause the hydrogen internal combustion engine to operate in a first engine operating mode when the performance value does not exceed the threshold, and cause the hydrogen internal combustion engine to operate in a second engine operating mode when the performance value exceeds the threshold.

Abstract: The present disclosure provides viral vectors which decrease undesired or off-target gene expression. Particularly, the present disclosure provides recombinant viral vectors comprising a transcription termination sequence adjacent to an inverted terminal repeat sequence (e.g., downstream of a first inverted terminal repeat sequence and upstream of an expression cassette), and virus or virus-like particles, compositions, and methods of using thereof.

Abstract: Provided are compositions, devices and systems, methods for assessing, treating and/or preventing an intraocular disease or disorder in a subject, wherein the etiology of the intraocular disease or disorder comprises infection of a microorganism in the intraocular space or cavity of the subject. Provided are compositions, devices and systems, and methods for assessing, treating and/or preventing age-related macular degeneration (AMD) in a subject, e.g., a human patient.

Abstract: Systems and methods described herein relate to the real-time verification of data purges. A first subprocess of a data purging process is executed to purge a plurality of data items. A system accesses purge result data providing an indication of a result of the first subprocess. The system determines, based on the purge result data, that the first subprocess was not executed in accordance with a purge policy associated with the data purging process. In response to determining that the first subprocess was not executed in accordance with the purge policy, the system adjusts a state of the data purging process. A second subprocess of the data purging process is then executed according to the adjusted state.

Abstract: The present invention relates to a conjugate that specifically targets a calcineurin inhibitor to T cells, such as Th17 cells, for use in a method for the treatment of an inflammatory disease. The invention also relates to a method for treating an inflammatory disease by administering a conjugate that specifically targets a calcineurin inhibitor to T cells, such as Th17 cells. In addition, the invention relates to a method for identifying a subject likely to be resistant to steroid treatment, as well as a subject likely to benefit from treatment with a calcineurin inhibitor.

Abstract: A fan blade includes a hub and a blade connected to a circumferential side face of the hub. The blade presents a circular shape, the inner annular surface of the blade encloses a hollow area. In the radial direction of the hub, an end of the blade connected to the hub is the root part of the blade. In a direction from the end part to the root part, at least a portion of the area of the blade is a first segment part that includes a first inner annular surface and a first outer annular surface. In the axial direction of the hub, the first inner annular surface and the first outer annular surface turn direction at the end part, and the first inner annular surface and the first outer annular surface on both sides of the end part do not overlap.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may receive one or more of an indication of a set of timing offset values associated with a hybrid automatic repeat request acknowledgment (HARQ-ACK) codebook or information associated with a set of start and length indicator values (SLIVs) for candidate data channels associated with the HARQ-ACK codebook. The UE may transmit the HARQ-ACK codebook, the HARQ-ACK codebook being based at least in part on one or more of distinct values of the set of timing offset values or distinct values of the set of SLIVs. Numerous other aspects are described.

Abstract: Systems and methods described herein relate to the prediction of effects of data purging on data sources that are related through hierarchical data relationships. A purge request comprises a set of purge parameters that identify a data source and define one or more purge criteria for purging of data items of the data source. A plurality of impacted data sources is identified based on one or more hierarchical data relationships held by the data items of the data source. The impacted data sources include the data source and one or more additional data sources. The purge parameters are provided to a machine learning model to obtain output indicative of a predicted effect of execution of the purge request on the impacted data sources. The predicted effect is caused to be presented at the user device prior to the execution of the purge request.

Abstract: A sealing device, comprising includes a sealing ring including a sealing lip composed of an insulating elastic material for forming dynamic sealing with respect to a conductive component; a support body fixed on the sealing ring along the circumferential direction of the sealing ring, and a first detection unit comprising two first support bodies in the support body, first cables respectively electrically connected to the corresponding first support bodies, and a loop detection device electrically connected to the first cables, wherein the first support bodies are arranged at the sealing ring such that radial ends of the first support bodies close to the conductive component are covered with the insulating elastic material at the sealing lip and can directly contact the conductive component after the sealing lip is worn. The two first support bodies, the conductive component, the loop detection device, and the first cables jointly form a communication loop.

Abstract: Systems and methods described herein relate to the real-time verification of data purges. A first subprocess of a data purging process is executed to purge a plurality of data items. A system accesses purge result data providing an indication of a result of the first subprocess. The system determines, based on the purge result data, that the first subprocess was not executed in accordance with a purge policy associated with the data purging process. In response to determining that the first subprocess was not executed in accordance with the purge policy, the system adjusts a state of the data purging process. A second subprocess of the data purging process is then executed according to the adjusted state.

Abstract: A split type precisely-anchorable transcatheter valve-in-ring system comprises a split transcatheter valve-in-ring anchoring stent (10) and a transcatheter artificial biological valve-in-ring (20), wherein the shape and structure of the transcatheter valve-in-ring anchoring stent (10) are matched with the real structure of the annuloplasty ring and supravalvular and infravalvular tissues after three-dimensional reconstruction based on imaging data of a patient who have undergone valve failure after implantation of a annuloplasty ring (30), the transcatheter valve-in-ring anchoring stent (10) is firstly delivered to the patient's failed annuloplasty ring for release, deformation and alignment with the supravalvular and infravalvular tissues of the failed annuloplasty ring; the transcatheter artificial biological valve-in-ring (20) is delivered to the transcatheter valve-in-ring anchoring stent (10) for release, the stent of the transcatheter artificial biological valve-in-ring (20) deforms and expands to the f

Abstract: Systems and methods described herein relate to the efficient handling of data purge requests in the context of a distributed storage system. A plurality of data purge requests is stored in a first data structure. The data purge requests may be grouped into batches that are processed at least partially in parallel. A first data purge request from the plurality of data purge requests is successfully processed, and is moved from the first data structure to a second data structure. Processing of a second data purge request from the plurality of data purge requests is unsuccessful. The second data purge request is retained in the first data structure. Purge status data is generated based on the first data purge request being in the second data structure and the second data purge request being in the first data structure. The purge status data may be presented at a user device.

Abstract: Systems and methods described herein relate to the efficient handling of data purge requests in the context of a distributed storage system. A plurality of data purge requests is stored in a first data structure. The data purge requests may be grouped into batches that are processed at least partially in parallel. A first data purge request from the plurality of data purge requests is successfully processed, and is moved from the first data structure to a second data structure. Processing of a second data purge request from the plurality of data purge requests is unsuccessful. The second data purge request is retained in the first data structure. Purge status data is generated based on the first data purge request being in the second data structure and the second data purge request being in the first data structure. The purge status data may be presented at a user device.

Abstract: The present disclosure provides a treatment method for retinal degeneration. The method includes administering an inhibitor or microbicid for a microorganism to eyes or a gastrointestinal tract of a patient. Specifically, the present disclosure proves that the inhibitor or microbicid may be used as a drug for treating a retinal degeneration disease by establishing an eye disease model or an eye disease model carrier, especially, a retinal degeneration model or model carrier.