Patents by Inventor Laiman Xiang

Laiman Xiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IRTA2 antibodies and methods of use
    Patent number: 7999077
    Abstract: Antibodies that specifically bind the extracellular domain of IRTA2 are disclosed herein. In one embodiment, these antibodies do not specifically bind IRTA1, IRTA3, IRTA4, or IRTA5. In one example, the antibodies are humanized antibodies. The antibodies can be conjugated to effector molecules, including detectable labels, radionucleotides, toxins and chemotherapeutic agents. The antibodies that specifically bind IRTA2 are of use to detect B cell malignancies, such as hairy cell leukemia and non-Hodgkin's lymphoma. These antibodies that specifically bind IRTA2 are also of use to treat B cell malignancies that express IRTA2, such as hairy cell leukemia and non-Hodgkin's lymphoma.
    Type: Grant
    Filed: September 22, 2005
    Date of Patent: August 16, 2011
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Ira Pastan, Tomoko Ise, Laiman Xiang, Satoshi Nagata
  • Irta2 Antibodies and Methods of Use
    Publication number: 20080292632
    Abstract: Antibodies that specifically bind the extracellular domain of IRTA2 are disclosed herein. In one embodiment, these antibodies do not specifically bind IRTA1, IRTA3, IRTA4, or IRTA5. In one example, the antibodies are humanized antibodies. The antibodies can be conjugated to effector molecules, including detectable labels, radionucleotides, toxins and chemotherapeutic agents. The antibodies that specifically bind IRTA2 are of use to detect B cell malignancies, such as hairy cell leukemia and non-Hodgkin's lymphoma. These antibodies that specifically bind IRTA2 are also of use to treat B cell malignancies that express IRTA2, such as hairy cell leukemia and non-Hodgkin's lymphoma.
    Type: Application
    Filed: September 22, 2005
    Publication date: November 27, 2008
    Inventors: Ira Pastan, Tomoko Ise, Laiman Xiang, Satoshi Nagata