Patents by Inventor Lain-Yen Hu

Lain-Yen Hu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7799823
    Abstract: The present invention is directed to a new class of benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: September 21, 2010
    Assignee: Warner-Lambert Company LLC
    Inventors: Stephen Douglas Barrett, Victor Fedij, Lain-Yen Hu, Donna M Iula, Bruce A Lefker, Raj Kumar Raheja, Karen Sexton, Jennifer Ann Van Camp
  • Patent number: 7674819
    Abstract: The present invention is directed to a new class of benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
    Type: Grant
    Filed: May 2, 2006
    Date of Patent: March 9, 2010
    Assignee: Warner-Lambert Company LLC
    Inventors: Stephen Douglas Barrett, Victor Fedij, Lain-Yen Hu, Donna M. Iula, Bruce A. Lefker, Raj Kumar Raheja, Karen Sexton, Jennifer Ann Van Camp
  • Patent number: 7670613
    Abstract: The present invention is directed to a new class of 4-cycloalkoxy benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
    Type: Grant
    Filed: July 5, 2005
    Date of Patent: March 2, 2010
    Assignee: Pfizer Inc.
    Inventors: Lain-Yen Hu, Bruce A. Lefker, Daniel Y. Du, Yvonne Dorothy Smith, Huangshu Lei, William Glen Harter, Victoria Leigh Downs, Mark L. Boys, Donna Michele Iula
  • Publication number: 20100048517
    Abstract: The present invention is directed to a new class of 4-cycloalkoxy benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
    Type: Application
    Filed: November 5, 2009
    Publication date: February 25, 2010
    Inventors: Lain-Yen Hu, Bruce A. Lefker, Daniel Y. Du, Yvonne Dorothy Smith, Huangshu Lei, William Glen Harter, Victoria Leigh Downs, Mark L. Boys, Donna Michele Iula
  • Patent number: 7576128
    Abstract: The present invention is directed to a new class of 4-oxo-benzonitriles, their use as androgen modulators, and to their use in the treatment of alopecia.
    Type: Grant
    Filed: February 8, 2005
    Date of Patent: August 18, 2009
    Assignee: Pfizer Inc.
    Inventors: Lain-Yen Hu, Huangshu Lei, Daniel Y. Du, Bruce A. Lefker
  • Publication number: 20090192202
    Abstract: The present invention is directed to a new class of 4-cyano-phenoxy-alkyl carboxyl derivatives and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
    Type: Application
    Filed: February 9, 2009
    Publication date: July 30, 2009
    Inventors: Lain-Yen Hu, Huangshu Lei, Daniel Y. Du, Bruce A. Lefker, Yvonne Dorothy Smith, Victor Fedij
  • Publication number: 20090170886
    Abstract: The present invention is directed to a new class of benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
    Type: Application
    Filed: July 7, 2006
    Publication date: July 2, 2009
    Inventors: Mark Laurence Boys, Michelle Marie Bruendl, Victoria Leigh Downs, Stephen Alan Fakhoury, William Glen Harter, Lain-Yen Hu, Sandra Marie Jennings, Bruce Allen Lefker, Lorna Helen Mitchell, Raj Kumar Raheja, Yvonne Dorothy Smith
  • Publication number: 20090105349
    Abstract: The present invention is directed to the discovery of a new class of androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease sebum secretion and to stimulate hair growth.
    Type: Application
    Filed: August 8, 2005
    Publication date: April 23, 2009
    Applicant: WARNER-LAMBERT COMPANY LLC
    Inventors: Nicole Chantel Barvian, Daniel Yunlong Du, Lain-Yen Hu, Donna Michele Iula, Bruce Allen Lefker, Huangshu Lei, Raj Kumar Raheja, Yvonne Dorothy Smith
  • Patent number: 7507860
    Abstract: The present invention is directed to a new class of 4-cyano-phenoxy-alkyl carboxyl derivatives and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: March 24, 2009
    Assignee: Pfizer Inc.
    Inventors: Lain-Yen Hu, Huangshu Lei, Daniel Y. Du, Bruce A. Lefker, Yvonne Dorothy Smith, Victor Fedij
  • Patent number: 7473711
    Abstract: The present invention is directed to a class of 4-cyano-phenoxy derivatives of formula I and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
    Type: Grant
    Filed: April 15, 2005
    Date of Patent: January 6, 2009
    Assignee: Pfizer Inc.
    Inventors: Lain-Yen Hu, Huangshu Lei, Daniel Y. Du, Bruce A. Lefker
  • Patent number: 7351743
    Abstract: The present invention provides therapeutically useful substituted guanidines, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such guanidines.
    Type: Grant
    Filed: August 11, 2000
    Date of Patent: April 1, 2008
    Assignee: Wyeth
    Inventors: Stanley M. Goldin, James B. Fischer, Andrew Gannett Knapp, N. Laxma Reddy, David Berlove, Graham J. Durant, Subbarao Katragadda, Lain-Yen Hu, Sharad Magar, Wenhong Fan, Elizabeth Yost, Juo Qing Guo
  • Publication number: 20070265348
    Abstract: The present invention provides therapeutically useful substituted guanidines, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such guanidines.
    Type: Application
    Filed: July 19, 2007
    Publication date: November 15, 2007
    Inventors: Stanley Goldin, James Fischer, Andrew Knapp, N. Laxma Reddy, David Berlove, Graham Durant, Subbarao Katragadda, Lain-Yen Hu, Sharad Magar, Wenhong Fan, Elizabeth Yost, Jun Qing Guo
  • Publication number: 20070207987
    Abstract: The present invention is directed to a new class of benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
    Type: Application
    Filed: August 22, 2005
    Publication date: September 6, 2007
    Applicant: WARNER-LAMBERT COMPANY LLC
    Inventors: Stephen Barrett, Daniel Du, Lain-Yen Hu
  • Publication number: 20070197642
    Abstract: The present invention is directed to a class of 4-cyano-phenoxy derivatives of formula I and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
    Type: Application
    Filed: April 15, 2005
    Publication date: August 23, 2007
    Inventors: Lain-Yen Hu, Huangshu Lei, Daniel Du, Bruce Lefker
  • Publication number: 20070197641
    Abstract: The present invention is directed to a new class of 4-cyano-phenoxy-alkyl carboxyl derivatives and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
    Type: Application
    Filed: April 1, 2005
    Publication date: August 23, 2007
    Inventors: Lain-Yen Hu, Huangshu Lei, Daniel Du, Bruce Lefker, Yvonne Smith, Victor Fedij
  • Publication number: 20070129409
    Abstract: The present invention is directed to a new class of 5-cyano-2-amino pyridines and to their use as androgen receptor modulators. A further aspect of the invention is directed to a new animal model for finding compounds capable of alleviating androgenic alopecia.
    Type: Application
    Filed: November 8, 2004
    Publication date: June 7, 2007
    Inventors: Lain-Yen Hu, Daniel Du, Huangshu Lei, Wen-Song Yue
  • Publication number: 20070072936
    Abstract: The present invention is directed to a new class of benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
    Type: Application
    Filed: November 7, 2006
    Publication date: March 29, 2007
    Applicant: WARNER-LAMBERT COMPANY LLC
    Inventors: Stephen Barrett, Victor Fedij, Lain-Yen Hu, Donna Iula, Bruce Lefker, Raj Raheja, Karen Sexton, Jennifer Van Camp
  • Publication number: 20060252796
    Abstract: The present invention is directed to a new class of benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
    Type: Application
    Filed: May 2, 2006
    Publication date: November 9, 2006
    Inventors: Stephen Barrett, Victor Fedij, Lain-Yen Hu, Donna Iula, Bruce Lefker, Raj Raheja, Karen Sexton, Jennifer Van Camp
  • Patent number: 6989448
    Abstract: The present invention provides compounds that block calcium channels having the Formula I shown below. The present invention also provides methods of using the compounds of Formula I to treat stroke, cerebral ischemia, head trauma, asthma, amyotropic lateral sclerosis, or epilepsy and to pharmaceutical compositions that contain the compounds of Formula I.
    Type: Grant
    Filed: September 25, 2002
    Date of Patent: January 24, 2006
    Inventors: Lain-Yen Hu, Michael Francis Rafferty, Todd Robert Ryder, Anthony Denver Sercel, Yuntao Song
  • Publication number: 20060009427
    Abstract: The present invention is directed to a new class of 4-cycloalkoxy benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
    Type: Application
    Filed: July 5, 2005
    Publication date: January 12, 2006
    Inventors: Lain-Yen Hu, Bruce Lefker, Daniel Du, Yvonne Smith, Huangshu Lei, William Harter, Victoria Downs, Mark Boys, Donna Iula