Patents by Inventor Lajos Hegedus
Lajos Hegedus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240101171Abstract: A digital train brake testing and train preparation assistant uses a system, method, and computer program for determining a component parameter of a train. The system may include sensor nodes mounted to a respective part of the train, wherein the sensor nodes form a sensor network on a rail car, wherein railcars form a wireless mesh network, and wherein each of the sensor nodes is configured to collect data of the component of the respective part of the train and to publish the collected data into the wireless mesh network. The system may further include a server system configured to receive the published data of the wireless mesh network and to determine the component parameter of the train based on the received data. Furthermore, a user device for displaying a component parameter determined by a system, method, and computer program for determining a component parameter of a train is provided.Type: ApplicationFiled: November 12, 2021Publication date: March 28, 2024Inventors: Balazs LIKTOR, Istvan HEGEDÜS, Lajos GATHY, Laszlo KOVACS, Gabor TOTH
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Patent number: 8946167Abstract: The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance (having low aqueous solubility and a substantial binding affinity to plasma proteins) and a plasma protein fraction in controlled aggregation state, whereby the said active substance and the said protein fraction are bound to each other by way of non-covalent bonds. It also covers processes for the preparation of the product and pharmaceutical formulation by dissolving the water-insoluble active substance in a water-miscible, pharmaceutically acceptable solvent, combining said solution with the aqueous solution of a plasma protein fraction in controlled aggregation state whereby a true solution is obtained containing the said active substance and the said protein fraction bound together by way of non-covalent bonds.Type: GrantFiled: February 9, 2009Date of Patent: February 3, 2015Assignee: Teva Pharmaceutical Industries Ltd.Inventors: Lajos Hegedus, Krisztina Krempels, Krisztina Paal, Gabor Petho
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Patent number: 7811599Abstract: Medical combination and its method of topical use comprising active ingredients which are sparingly soluble in water, preferably in one single composition against microbes which are pathogenic in humans and animals and which usually appear together.Type: GrantFiled: November 8, 2002Date of Patent: October 12, 2010Inventors: Károly Lukács, Károlyné Lukács, Lajos Hegedüs, Levente Dajka, Krisztina Krempels, József Muller
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Publication number: 20100076008Abstract: The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance (having low aqueous solubility and a substantial binding affinity to plasma proteins) and a plasma protein fraction in controlled aggregation state, whereby the said active substance and the said protein fraction are bound to each other by way of non-covalent bonds. It also covers processes for the preparation of the product and pharmaceutical formulation by dissolving the water-insoluble active substance in a water-miscible, pharmaceutically acceptable solvent, combining said solution with the aqueous solution of a plasma protein fraction in controlled aggregation state whereby a true solution is obtained containing the said active substance and the said protein fraction bound together by way of non-covalent bonds.Type: ApplicationFiled: February 9, 2009Publication date: March 25, 2010Inventors: Lajos Hegedus, Krisztina Krempels, Krisztina Paal, Gabor Petho
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Patent number: 7501455Abstract: The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance (having low aqueous solubility and a substantial binding affinity to plasma proteins) and a plasma protein fraction in controlled aggregation state, whereby the said active substance and the said protein fraction are bound to each other by way of non-covalent bonds. It also covers processes for the preparation of the product and pharmaceutical formulation by dissolving the water-insoluble active substance in a water-miscible, pharmaceutically acceptable solvent, combining said solution with the aqueous solution of a plasma protein fraction in controlled aggregation state whereby a true solution is obtained containing the said active substance and the said protein fraction bound together by way of non-covalent bonds.Type: GrantFiled: March 17, 2004Date of Patent: March 10, 2009Assignee: Sicor, Inc.Inventors: Lajos Hegedus, Krisztina Krempels, Krisztina Paal, Gabor Petho
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Publication number: 20070232536Abstract: The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance (having low aqueous solubility and a substantial binding affinity to plasma proteins) and a plasma protein fraction in controlled aggregation state, whereby the said active substance and the said protein fraction are bound to each other by way of non-covalent bonds. It also covers processes for the preparation of the product and pharmaceutical formulation by dissolving the water-insoluble active substance in a water-miscible, pharmaceutically acceptable solvent, combining said solution with the aqueous solution of a plasma protein fraction in controlled aggregation state whereby a true solution is obtained containing the said active substance and the said protein fraction bound together by way of non-covalent bonds.Type: ApplicationFiled: October 10, 2006Publication date: October 4, 2007Inventors: Lajos Hegedus, Krisztina Krempels, Krisztina Paal, Gabor Petho
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Patent number: 7119124Abstract: The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance (having low aqueous solubility and a substantial binding affinity to plasma proteins) and a plasma protein fraction in controlled aggregation state, whereby the said active substance and the said protein fraction are bound to each other by way of non-covalent bonds. It also covers processes for the preparation of the product and pharmaceutical formulation by dissolving the water-insoluble active substance in a water-miscible, pharmaceutically acceptable solvent, combining said solution with the aqueous solution of a plasma protein fraction in controlled aggregation state whereby a true solution is obtained containing the said active substance and the said protein fraction bound together by way of non-covalent bonds.Type: GrantFiled: January 21, 2003Date of Patent: October 10, 2006Assignee: Human Rt.Inventors: Lajos Hegedus, Krisztina Krempels, Krisztina Paal, Gabor Petho
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Publication number: 20050282734Abstract: An optically clear, pharmaceutically acceptable aqueous composition comprising paclitaxel or a derivative thereof, serum albumin and a pharmaceutically acceptable vehicle, wherein the composition comprises no more than 10% organic solvent and has a pH of about 3.0 to about 4.8, is described. The serum albumin can be fatted or defatted, and the composition can optionally be lyophilized or optionally lyophilized and reconstituted. At least 70% of the paclitaxel is bound to serum albumin, the ratio of paclitaxel to albumin is at least about 1:5, and the concentration of paclitaxel is at least about 25 ?g/ml. Methods of making and using this composition an also provided.Type: ApplicationFiled: March 23, 2005Publication date: December 22, 2005Inventors: Tenshuk Kadima, Howard Kaplan, Robert Tuttle, Lajos Hegedus, Krisztina Krempels, Krisztina Paal, Gabor Petho
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Publication number: 20050064028Abstract: The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance (having low aqueous solubility and a substantial binding affinity to plasma proteins) and a plasma protein fraction in controlled aggregation state, whereby the said active substance and the said protein fraction are bound to each other by way of non-covalent bonds. It also covers processes for the preparation of the product and pharmaceutical formulation by dissolving the water-insoluble active substance in a water-miscible, pharmaceutically acceptable solvent, combining said solution with the aqueous solution of a plasma protein fraction in controlled aggregation state whereby a true solution is obtained containing the said active substance and the said protein fraction bound together by way of non-covalent bonds.Type: ApplicationFiled: March 17, 2004Publication date: March 24, 2005Inventors: Lajos Hegedus, Krisztina Krempels, Krisztina Paal, Gabor Petho
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Publication number: 20050043222Abstract: Medical combination and its method of topical use comprising active ingredients which are sparingly soluble in water, preferably in one single composition against microbes which are pathogenic in humans and animals and which usually appear together.Type: ApplicationFiled: November 8, 2002Publication date: February 24, 2005Inventors: Karoly Lukacs, Karolyne Lukacs, Lajos Hegedus, Levente Dajka, Krisztina Krempels, Jozsef Muller
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Patent number: 6743826Abstract: The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance (having low aqueous solubility and a substantial binding affinity to plasma proteins) and a plasma protein fraction in controlled aggregation state, whereby the said active substance and the said protein fraction are bound to each other by way of non-covalent bonds. It also covers processes for the preparation of the product and pharmaceutical formulation by dissolving the water-insoluble active substance in a water-miscible; pharmaceutically acceptable solvent, combining said solution with the aqueous solution of a plasma protein fraction in controlled aggregation state whereby a true solution is obtained containing the said active substance and the said protein fraction bound together by way of non-covalent bonds.Type: GrantFiled: April 27, 1999Date of Patent: June 1, 2004Assignee: Human RTInventors: Lajos Hegedus, Krisztina Krempels, Krisztina Paal, Gabor Petho
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Publication number: 20040014655Abstract: The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance (having low aqueous solubility and a substantial binding affinity to plasma proteins) and a plasma protein fraction in controlled aggregation state, whereby the said active substance and the said protein fraction are bound to each other by way of non-covalent bonds. It also covers processes for the preparation of the product and pharmaceutical formulation by dissolving the water-insoluble active substance in a water-miscible, pharmaceutically acceptable solvent, combining said solution with the aqueous solution of a plasma protein fraction in controlled aggregation state whereby a true solution is obtained containing the said active substance and the said protein fraction bound together by way of non-covalent bonds.Type: ApplicationFiled: January 21, 2003Publication date: January 22, 2004Inventors: Lajos Hegedus, Krisztina Krempels, Krisztina Paal, Gabor Petho