Patents by Inventor Lajos T. Nagy

Lajos T. Nagy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluoropyrrolidines having dipeptidyl peptidase enzyme inhibitory activity
    Patent number: 8063045
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Grant
    Filed: February 1, 2010
    Date of Patent: November 22, 2011
    Assignee: Sanofi-Aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Karoly Kanai, Zoltan Kapui, Edit Susan, Tibor Szabo, Lajos T. Nagy, Katalin Urban-Szabo, Marton Varga
  • Amino-alkyl amide derivatives as CCR3 receptor ligands
    Patent number: 8044078
    Abstract: The invention relates to a compound of the general formula (I), as defined herein which is useful for the treatment of a pathology in a patient wherein a CCR3 receptor plays a role in the development of the pathology, and pharmaceutical preparations containing such compound. The invention is also directed to a process for preparing the compound of the general formula (I), and intermediate useful in the preparation.
    Type: Grant
    Filed: March 19, 2008
    Date of Patent: October 25, 2011
    Assignee: Sanofi-Aventis
    Inventors: Agnes Pappne Behr, Zoltan Kapui, Peter Aranyi, Sandor Batori, Veronika Bartane Bodor, Lajos T. Nagy, Mihalyne Santa, legal representative, Marton Varga, Endre Mikus, Katalin Urban-Szabo, Judit Vargane Szeredi, Tibor Szabo, Edit Susan, Marianna Kovacs
  • Compounds
    Patent number: 7781455
    Abstract: Heterocyclic amides useful as inhibitors of dipeptylpeptidase-IV (DPP-IV) enzyme, process for the preparation thereof and intermediates therefore.
    Type: Grant
    Filed: June 11, 2003
    Date of Patent: August 24, 2010
    Assignee: sanofi-aventis
    Inventors: Péter Arányi, László Balázs, Imre Bata, Sándor Bátori, Éva Boronkay, Zoltán Kapui, Edit Susán, Tibor Szabó, Lajos T. Nagy, Katalin Urbán-Szabó, Márton Varga
  • FLUOROPYRROLIDINES HAVING DIPEPTIDYL PEPTIDASE ENZYME INHIBITORY ACTIVITY
    Publication number: 20100210838
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Application
    Filed: February 1, 2010
    Publication date: August 19, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Peter Arányi, László Balázs, Imre Bata, Sándor Bátori, Éva Boronkay, Philippe Bovy, Károly Kánai, Zoltán Kapui, Edit Susán, Tibor Szabó, Lajos T. Nagy, Katalin Urbán-Szabó, Márton Varga
  • Triazolo-quinolin derivatives useful as adenosine receptor ligands
    Patent number: 7713992
    Abstract: The present invention relates to adenosine A3 receptor ligands of the general formula (I), within those preferably antagonists, as well as their salts, solvates and isomers, and the pharmaceutical compositions containing them, to the use of the compounds of the general formula (I), as well as their salts, solvates and isomers, to the preparation of the compounds of the general formula (I) and their salts, solvates and isomers, furthermore to the new intermediates of the general formulae (II) and to the preparation thereof.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: May 11, 2010
    Assignee: sanofi-aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Sandor Batori, Judit Bence, Kinga Boer, Felix Hajdu, Zoltan Kapui, Endre Mikus, Tibor Szabo, Lajos T. Nagy, Geza Timari, Katalin Urban-Szabo, Erzsebet Walcz
  • Imidazoquinoline derivatives as adenosine A3 receptor ligands
    Patent number: 7709489
    Abstract: This invention is directed to a compound of formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, Z, m, n, o, p and r are as defined herein, its preparation, pharmaceutical composition and use as an adenosine A3 receptor ligand preferably an antagonist.
    Type: Grant
    Filed: June 17, 2008
    Date of Patent: May 4, 2010
    Assignee: sanofi-aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Maria Balogh, Sandor Batori, Lajos T. Nagy, Geza Timari, Kinga Boer, Zoltan Kapui, Endre Mikus, Katalin Gerber, Judit Vargane Szeredi, Katalin Urban-Szabo, Erzsebet Walcz
  • Fluoropyrrolidines having dipeptidyl peptidase enzyme inhibitory activity
    Patent number: 7655663
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Grant
    Filed: March 5, 2008
    Date of Patent: February 2, 2010
    Assignee: sanofi-aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Karoly Kanai, Zoltan Kapui, Edit Susan, Tibor Szabo, Lajos T. Nagy, Katalin Urban-Szabo, Marton Varga
  • Imidazoquinoline derivatives as adenosine A3 receptor ligands
    Patent number: 7419977
    Abstract: This invention is directed to a compound of formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, Z, m, n, o, p and r are as defined herein, its preparation, pharmaceutical composition and use as an adenosine A3 receptor ligand preferably an antagonist.
    Type: Grant
    Filed: May 16, 2005
    Date of Patent: September 2, 2008
    Assignee: Sanofi-Aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Maria Balogh, Sandor Batori, Lajos T. Nagy, Geza Timari, Kinga Boer, Zoltan Kapui, Endre Mikus, Katalin Gerber, Judit Vargane Szeredi, Katalin Urban Szabo, Erzsebet Walcz
  • FLUOROPYRROLIDINES HAVING DIPEPTIDYL PEPTIDASE ENZYME INHIBITORY ACTIVITY
    Publication number: 20080161310
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Application
    Filed: March 5, 2008
    Publication date: July 3, 2008
    Applicant: Sanofi-Aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Karoly Kanai, Zoltan Kapui, Edit Susan, Tibor Szabo, Lajos T. Nagy, Katalin Urban-Szabo, Marton Varga
  • Triazolo-Quinolin Derivatives Useful as Adenosine Receptor Ligands
    Publication number: 20080146604
    Abstract: The present invention relates to adenosine A3 receptor ligands of the general formula (I), within those preferably antagonists, as well as their salts, solvates and isomers, and the pharmaceutical compositions containing them, to the use of the compounds of the general formula (I), as well as their salts, solvates and isomers, to the preparation of the compounds of the general formula (I) and their salts, solvates and isomers, furthermore to the new intermediates of the general formulae (II) and to the preparation thereof.
    Type: Application
    Filed: February 28, 2008
    Publication date: June 19, 2008
    Applicant: Sanofi-Aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Sandor Batori, Judit Bence, Kinga Boer, Felix Hajdu, Zoltan Kapui, Endre Mikus, Tibor Szabo, Lajos T. Nagy, Geza Timari, Katalin Urban-Szabo, Erzsebet Walcz
  • Triazolo-quinolin derivatives useful as adenosine receptor ligands
    Patent number: 7365089
    Abstract: The present invention relates to adenosine A3? receptor ligands of the general formula (I), within those preferably antagonists, as well as their salts, solvates and isomers, and the pharmaceutical compositions containing them, to the use of the compounds of the general formula (I), as well as their salts, solvates and isomers, to the preparation of the compounds of the general formula (I) and theirs salts, solvates and isomers, furthermore to the new intermediates of the general formulae (II) and to the preparation thereof.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: April 29, 2008
    Assignee: Sanofi-Aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Sandor Batori, Judit Bence, Kinga Boer, Felix Hajdu, Zoltan Kapui, Endre Mikus, Tibor Szabo, Lajos T. Nagy, Geza Timari, Katalin Urban-Szabo, Erzsebet Walcz
  • Compounds
    Patent number: 7348327
    Abstract: The present invention relates to new, potent DPP-IV enzyme inhibitors of the general formula (I), which contain fluorine atoms.
    Type: Grant
    Filed: March 4, 2003
    Date of Patent: March 25, 2008
    Assignee: Sanofi-Aventis
    Inventors: Peter Aranyi, Laszlo Balazs, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Karoly Kanai, Zoltan Kapui, Edit Susan, Tibor Szabo, Lajos T. Nagy, Katalin Urban-Szabo, Marton Varga
  • Aminoquinoline and aminopyridine derivatives and their use as adenosine a3 ligands
    Patent number: 6969723
    Abstract: Compounds of general formula (I), wherein R4 and R5 stand for hydrogen atom or form together an 1,3-butadienyl group, optionally substituted by a methylenedioxy group or one or more straight or branched C1-4 alkyl group, straight or branched C1-4 alkoxy group, hydroxy group or halogen atom; are strong adenosine A3 receptor ligands preferably antagonists.
    Type: Grant
    Filed: May 29, 2002
    Date of Patent: November 29, 2005
    Assignee: Sanofi - Aventis
    Inventors: Peter Arányi, László Balázs, Mária Balogh, Imre Bata, Sándor Bátori, Lajos T. Nagy, Geza Tímári, Kinga Boér, Olivier Finance, Zoltán Kapui, Endre Mikus, Zsuzsanna Szamosvölgyi, Gábor Szeleczky, Katalin Urbán-Szabó
  • Triazolo-quinolin derivatives useful as adenosine receptor ligands
    Publication number: 20050124648
    Abstract: The present invention relates to adenosine A-3? receptor ligands of the general formula (I), within those preferably antagonists, as well as their salts, solvates and isomers, and the pharmaceutical compositions containing them, to the use of the compounds of the general formula (I), as well as their salts, solvates and isomers, to the preparation of the compounds of the general formula (I) and theirs salts, solvates and isomers, furthermore to the new intermediates of the general formulae (II) and to the preparation thereof.
    Type: Application
    Filed: December 17, 2002
    Publication date: June 9, 2005
    Inventors: Peter Aranyi, Laszlo Balazs, Sandor Batori, Judit Bence, Kinga Boer, Felix Hadju, Zoltan Kapui, Endre Mikus, Tibor Szabo, Lajos T. Nagy, Geza Timari, Katalin Urban-Szabo, Erzsebet Walcz
  • Aminoquinoline and aminopyridine derivatives and their use as adenosine a3 ligands
    Publication number: 20040186133
    Abstract: Compounds of general formula (I), wherein R4 and R5 stand for hydrogen atom or form together an 1,3-butadienyl group, optionally substituted by a methylenedioxy group or one or more straight or branched C1-4 alkyl group, straight or branched C1-4 alkoxy group, hydroxy group or halogen atom; are strong adenosine A3 receptor ligands preferably antagonists.
    Type: Application
    Filed: May 13, 2004
    Publication date: September 23, 2004
    Inventors: Peter Aranyl, Laszlo Balazs, Maria Balogh, Imre Bata, Sandor Batori, Lajos T. Nagy, Geza Timari, Kinga Boer, Olivier Finance, Zoltan Kapul, Endre Mikus, Zsuzsanna Szamosvolgyi, Gabor Szeleczky, Katalin Urban-Szabo
  • SACCHARIN DERIVATIVES AS ORALLY ACTIVE ELASTASE INHIBITORS
    Publication number: 20030114449
    Abstract: Orally active compounds of general formula (I) wherein R1 is methyl, ethyl or 2-morpholino-ethyl group, R2 is piperidino, morpholino or 4-methyl-piperazinyl group, n is 2 or 3 and their salts, solvates and hydrates.
    Type: Application
    Filed: October 7, 2002
    Publication date: June 19, 2003
    Inventors: Peter Aranyi, Sandor Batori, Stephane Dessilla, Istvan Hermecz, Zoltan Kapui, Ferenc Levai, Endre Mikus, Marc Pascal, Lajos T. Nagy, Bruno Simonot, Katalin Urban Szabo, Marton Varga, Lelle Vasvarine Debreczy
  • Process for the preparation of N-phosphonomethyl-glycine
    Patent number: 4065491
    Abstract: The invention relates to a new and improved method for the preparation of N-phosphonomethyl-glycine, a potent pre-emergence herbicide. According to the invention glycine, formaldehyde and a dialkyl phosphite are condensed in an aqueous alkaline medium to form a N-phosphonomethyl-glycine dialkyl ester, and the diester is hydrolyzed with a mineral acid.
    Type: Grant
    Filed: January 12, 1977
    Date of Patent: December 27, 1977
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Todor Pfliegel, Jeno Seres, Antal Gajary, Klara Daroczy nee Csuka, Lajos T. Nagy