Patents by Inventor Lakhmir Chawla

Lakhmir Chawla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11583568
    Abstract: The present disclosure relates to the use of angiotensin II, angiotensin III, or angiotensin IV in therapeutic methods for the treatment of hypotension, especially catecholamine-resistant hypotension.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: February 21, 2023
    Assignee: La Jolla Pharma, LLC
    Inventors: Lakhmir Chawla, George Tidmarsh, Steve Ching Tsung Chen
  • Publication number: 20220323396
    Abstract: The present disclosure provides compositions and methods of treating a viral infection comprising administering an antiviral cocktail that includes a protease inhibitor and an anticoagulant agent, anti-inflammatory agent and/or an antiviral agent for conjoint administration to a subject.
    Type: Application
    Filed: April 4, 2022
    Publication date: October 13, 2022
    Inventor: LAKHMIR CHAWLA
  • Publication number: 20220273757
    Abstract: The present disclosure relates to the use of angiotensin II in therapeutic methods for the treatment of hypotension.
    Type: Application
    Filed: June 12, 2020
    Publication date: September 1, 2022
    Inventor: Lakhmir Chawla
  • Publication number: 20220031812
    Abstract: Aspects of the present disclosure relate generally to kits and methods for treating acute central nervous systems disorders with chimeric proteins and pharmaceutical compositions comprising such chimeric proteins.
    Type: Application
    Filed: July 30, 2021
    Publication date: February 3, 2022
    Inventors: Samuel J. Pfaff, Yan Zhang, Kristopher M. Kuchenbecker, Lakhmir Chawla
  • Patent number: 11219662
    Abstract: The present disclosure relates to the use of angiotensin II, angiotensin III, or angiotensin IV in therapeutic methods for the treatment of hypotension, especially catecholamine-resistant hypotension.
    Type: Grant
    Filed: March 4, 2021
    Date of Patent: January 11, 2022
    Assignee: La Jolla Pharma, LLC
    Inventors: George Tidmarsh, Lakhmir Chawla
  • Publication number: 20210369665
    Abstract: The present disclosure provides methods of treating a viral infection comprising administering a protease inhibitor, optionally conjointly with an anticoagulant therapy and/or antiviral agent.
    Type: Application
    Filed: May 25, 2021
    Publication date: December 2, 2021
    Inventors: James A. Wilkie, Lakhmir Chawla, Peter Jordan, Elaine C. Liong, Michelle M. Merrigan, Martha C. Farmer
  • Publication number: 20210187058
    Abstract: The present disclosure relates to the use of angiotensin II, angiotensin III, or angiotensin IV in therapeutic methods for the treatment of hypotension, especially catecholamine-resistant hypotension.
    Type: Application
    Filed: March 4, 2021
    Publication date: June 24, 2021
    Inventors: George Tidmarsh, Lakhmir Chawla
  • Publication number: 20210128690
    Abstract: The present disclosure relates to the use of hepcidin in therapeutic methods for the treatment of various conditions in which decreasing serum iron concentration may be beneficial.
    Type: Application
    Filed: December 19, 2017
    Publication date: May 6, 2021
    Inventors: Lakhmir Chawla, George Tidmarsh
  • Publication number: 20210030834
    Abstract: The present disclosure relates to the use of angiotensin II, angiotensin III, or angiotensin IV in therapeutic methods for the treatment of hypotension, especially catecholamine-resistant hypotension.
    Type: Application
    Filed: March 26, 2020
    Publication date: February 4, 2021
    Inventors: George Tidmarsh, Lakhmir Chawla
  • Publication number: 20200237853
    Abstract: The present disclosure relates to the use of angiotensin II in therapeutic methods for the treatment of hypotension, especially catecholamine-resistant hypotension.
    Type: Application
    Filed: April 17, 2020
    Publication date: July 30, 2020
    Inventors: George Tidmarsh, Lakhmir Chawla
  • Publication number: 20200222493
    Abstract: The present disclosure relates to the use of angiotensin II, angiotensin III, or angiotensin IV in therapeutic methods for the treatment of hypotension, especially catecholamine-resistant hypotension.
    Type: Application
    Filed: April 13, 2018
    Publication date: July 16, 2020
    Inventors: Lakhmir Chawla, George Tidmarsh, Steve Ching Tsung Chen
  • Patent number: 10500247
    Abstract: A method for treating a patient suffering from one of septic shock, acute kidney injury, severe hypotension, cardiac arrest, and refractory hypotension, but not from myocardial infarction, is provided. The method includes administering a therapeutically effective dose of Angiotensin II, or Ang II, to the patient.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: December 10, 2019
    Assignee: The George Washington University a Congressionally Chartered Not-for-Profit Corporation
    Inventor: Lakhmir Chawla
  • Publication number: 20190336583
    Abstract: The present disclosure relates to the use of hepcidin, mini-hepcidin, or a hepcidin analogue in therapeutic methods for the treatment and/or prevention of acquired iron overload or other conditions for which iron redistribution or sequestration is helpful.
    Type: Application
    Filed: January 18, 2018
    Publication date: November 7, 2019
    Inventors: George Tidmarsh, Lakhmir Chawla
  • Patent number: 10406201
    Abstract: The present disclosure relates to the use of angiotensin II, angiotensin III, or angiotensin IV in therapeutic methods for the treatment of hypotension, especially catecholamine-resistant hypotension.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: September 10, 2019
    Assignee: La Jolla Pharma, LLC
    Inventors: George Tidmarsh, Lakhmir Chawla
  • Publication number: 20190240292
    Abstract: The present disclosure relates to the use of hepcidin in therapeutic methods for the treatment of various conditions in which decreasing serum iron concentration may be beneficial.
    Type: Application
    Filed: March 21, 2019
    Publication date: August 8, 2019
    Inventors: George Tidmarsh, Lakhmir Chawla
  • Patent number: 10335451
    Abstract: A method for treating a patient suffering from one of septic shock, acute kidney injury, severe hypotension, cardiac arrest, and refractory hypotension, but not from myocardial infarction, is provided. The method includes administering a therapeutically effective dose of Angiotensin II, or Ang II, to the patient.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: July 2, 2019
    Assignee: The George Washington University a Congressionally Chartered Not-for-Profit Corporation
    Inventor: Lakhmir Chawla
  • Patent number: 10322160
    Abstract: A method for treating a patient suffering from one of septic shock, acute kidney injury, severe hypotension, cardiac arrest, and refractory hypotension, but not from myocardial infarction, is provided. The method includes administering a therapeutically effective dose of Angiotensin II, or Ang II, to the patient.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: June 18, 2019
    Assignee: The George Washington University a Congressionally Chartered Not-for-Profit Corporation
    Inventor: Lakhmir Chawla
  • Publication number: 20180344800
    Abstract: A method for treating a patient suffering from one of septic shock, acute kidney injury, severe hypotension, cardiac arrest, and refractory hypotension, but not from myocardial infarction, is provided. The method includes administering a therapeutically effective dose of Angiotensin II, or Ang II, to the patient.
    Type: Application
    Filed: August 7, 2018
    Publication date: December 6, 2018
    Applicant: The George Washington University a Congressionally Chartered Not-for-Profit Corporation
    Inventor: Lakhmir CHAWLA
  • Publication number: 20180311306
    Abstract: The present disclosure relates to the use of angiotensin II in therapeutic methods for the treatment of hypotension, especially catecholamine-resistant hypotension.
    Type: Application
    Filed: June 22, 2018
    Publication date: November 1, 2018
    Inventors: George Tidmarsh, Lakhmir Chawla
  • Patent number: 10028995
    Abstract: The present invention relates, inter alia, to a method comprising administering to a subject having high output shock and undergoing treatment with a catecholamine at a dose equivalent to at least about 0.2 mcg/kg/min of norepinephrine a dose of angiotensin II which is effective to raise the blood pressure of the subject to a mean arterial pressure (MAP) of about 65 mm or above, and which is effective to reduce the dose of the catecholamine required to maintain a MAP of about 65 mm to the equivalent of about 0.05-0.2 mcg/kg/min norepinephrine or less, or to the equivalent of about 0.05 mcg/kg/min norepinephrine or less.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: July 24, 2018
    Assignee: The George Washington University a Congressionally Chartered Not-for-Profit Corporation
    Inventor: Lakhmir Chawla