Patents by Inventor Lakshman Perera SAMARANAYAKE

Lakshman Perera SAMARANAYAKE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antifungal compound and uses thereof
    Patent number: 9642829
    Abstract: Disclosed herein is a novel antifungal compound, derivatives that are used to treat fungal infections. In a specific embodiment, the compound is a small molecule. In a specific embodiment, the compound described herein inhibits yeast to hypha transition under robust hyphal inducing conditions at lower concentration of the molecule. Also disclosed is a composition comprising the antifungal compound. In a specific embodiment, the composition is a pharmaceutical composition. Also disclosed is a method of treating and/or preventing fungal infection using the disclosed compound. The disclosed compound exhibits antifungal activity against wide range of fungal species at slightly higher concentrations. Antifungal compound disclosed herein is used as anti-biofilm agent against fungal infections.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: May 9, 2017
    Assignee: THE UNIVERSITY OF HONG KONG
    Inventors: Chaminda Jayampath Seneviratne, Yi Tsun Richard Kao, Lakshman Perera Samaranayake, Kwok Yung Yuen, Dan Yang, Yu Wang, Sze Wah Sarah Wong
  • ANTIFUNGAL COMPOUND AND USES THEREOF
    Publication number: 20140155478
    Abstract: Disclosed herein is a novel antifungal compound, derivatives that are used to treat fungal infections. In a specific embodiment, the compound is a small molecule. In a specific embodiment, the compound described herein inhibits yeast to hypha transition under robust hyphal inducing conditions at lower concentration of the molecule. Also disclosed is a composition comprising the antifungal compound. In a specific embodiment, the composition is a pharmaceutical composition. Also disclosed is a method of treating and/or preventing fungal infection using the disclosed compound. The disclosed compound exhibits antifungal activity against wide range of fungal species at slightly higher concentrations. Antifungal compound disclosed herein is used as anti-biofilm agent against fungal infections.
    Type: Application
    Filed: December 3, 2013
    Publication date: June 5, 2014
    Applicant: The University of Hong Kong
    Inventors: Chaminda Jayampath SENEVIRATNE, Yi Tsun Richard KAO, Lakshman Perera SAMARANAYAKE, Kwok Yung YUEN, Dan YANG, Yu WANG, Sze Wah Sarah WONG